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anti-Rat (Rattus) FOXO1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FOXO1 Antibody (supplied by: Log in to see )

Antigen
Forkhead Box O1 (FOXO1) Antibodies
  • Afxh
  • AI876417
  • fkh1
  • FKH1
  • fkhr
  • Fkhr
  • FKHR
  • Fkhr1
  • FOXO1
  • foxo1
  • FoxO1A
  • FOXO1A
  • foxo1a
  • Foxo1a
  • FoxO1a.1
  • xFoxO1
  • zgc:153388
Epitope
pSer319
52
35
25
24
20
18
16
14
11
10
9
8
6
5
5
5
5
4
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
407
194
167
20
17
10
4
3
3
2
1
1
1
1
1
Host
Rabbit
299
92
21
2
Clonality
Polyclonal
Conjugate
This FOXO1 antibody is un-conjugated
8
7
6
6
6
4
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
325
174
116
112
97
67
45
9
7
5
4
4
3
2
2
1
1
Supplier
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Catalog No. ABIN498786
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.2461331 ABIN498785 IHC (p) WB Rabbit pSer256 Log in to see Polyclonal
0.2461331 ABIN498199 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.2461331 ABIN498876 IHC (p) WB Rabbit Log in to see Polyclonal
0.2461331 ABIN498877 IHC (p) WB Rabbit Log in to see Polyclonal
0.2461331 ABIN784062 EIA IF IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
0.2461331 ABIN684733 IF (p) IHC (p) WB Rabbit IgG AA 315-325, pSer319 Log in to see Polyclonal
0.00089192734 ABIN196848 IF IHC (p) WB Rabbit pSer319 Log in to see Polyclonal 3
0.00089192734 ABIN196812 IF IHC (p) WB Rabbit pSer256 Log in to see Polyclonal 4
0.00089192734 ABIN257291 ICC IF IHC (p) IHC WB Rabbit IgG pSer256 Log in to see Polyclonal
0.00089192734 ABIN741720 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.00089192734 ABIN446789 ICC IF IHC (p) IHC WB Rabbit Log in to see Polyclonal
0.00089192734 ABIN1711769 IHC (p) WB HRP Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
0.00089192734 ABIN1700752 IHC (p) WB Biotin Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
0.00089192734 ABIN1734425 IF IHC (p) ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal
0.00089192734 ABIN1714254 IF (p) IHC (p) WB Rabbit IgG pSer322, pSer325 Log in to see Polyclonal
0.00089192734 ABIN741722 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.00089192734 ABIN741729 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.00089192734 ABIN1734422 IHC (p) Goat C-Term Log in to see Polyclonal
0.00089192734 ABIN1734423 ICC IHC (p) ELISA WB Rabbit IgG N-Term Log in to see Polyclonal
0.00089192734 ABIN1711768 IHC (p) WB HRP Rabbit IgG pSer329 Log in to see Polyclonal

Similar anti-FOXO1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 325 Antibodies 138 Antibodies 115 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies
Immunoprecipitation (IP) 8 Antibodies 1 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 98 Antibodies 35 Antibodies 27 Antibodies
Immunohistochemistry (IHC) 176 Antibodies 95 Antibodies 78 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies 2 Antibodies 2 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 45 Antibodies

General

Antigen Forkhead Box O1 (FOXO1) Antibodies
Epitope pSer319
(52), (35), (25), (24), (20), (18), (16), (14), (11), (10), (9), (8), (6), (5), (5), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(407), (194), (167), (20), (17), (10), (4), (3), (3), (2), (1), (1), (1), (1), (1)
Host Rabbit
(299), (92), (21), (2)
Clonality
Polyclonal
Conjugate This FOXO1 antibody is un-conjugated
(8), (7), (6), (6), (6), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(325), (174), (116), (112), (97), (67), (45), (9), (7), (5), (4), (4), (3), (2), (2), (1), (1)
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Product Details anti-FOXO1 Antibody

Target Details FOXO1 Application Details Handling Images
Specificity This antibody detects endogenous levels of p-FKHR/FOXO1A protein, only when phosphorylated at Ser319.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE

Target Details FOXO1

Product Details anti-FOXO1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name FOXO1A (FOXO1 Antibody Abstract)
Background The transcription factor forkhead in rhabdomyosarcoma (FKHR), which is inhibited by insulin and IGF-1, enhances transcription. FKHR has been implicated in alveolar rhabdomyosarcoma, a soft tissue tumor wherein a chromosomal translocation [t(2,12)(q35,q14)] occurs between the FKHR and PAX3 genes, resulting in a novel chimeric protein with abnormal levels of expression. FKHR becomes phosphorylated at Ser 319, Ser 256 and Thr 256 by protein kinase B (PKB) in a phosphoinsoditide 3 (PI 3)-kinase/Akt-dependent pathway, resulting in the inactivation and subsequent nuclear exit of FKHR. In addition, FKHR becomes phosphorylated at Ser 329, also resulting in decreased FKHR activity and diminished nuclear FKHR concentration. However, phosphorylation of FKHR at Ser 329 is not mediated by a PI 3-kinasedependent pathway, but by an alternate mechanism. Dualspecificity tyrosine-phosphorylated and regulated kinase 1A (DYRK1A), which co-localizes to the same region of the nucleus as FKHR, specifically phosphorylates FKHR at Ser 329 in rabbit skeletal muscle.Synonyms: FKHR, FOXO1, Forkhead Box Protein O1, Forkhead Box Protein O1A, Forkhead in Rhabdomyosarcoma
Molecular Weight approx. 70 to 82 kDa
Gene ID 2308
NCBI Accession NP_002006
UniProt Q12778
Research Area Cancer, Transcription Factors
Pathways PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-FOXO1 Antibody Target Details FOXO1 Handling Images back to top
Application Notes Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-FOXO1 Antibody Target Details FOXO1 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-FOXO1 Antibody Target Details FOXO1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FOXO1 antibody (Forkhead Box O1) (pSer319) (ABIN498786) Immunohistochemistry (IHC) analyzes of p-FKHR/FOXO1A antibody in paraffin-embe...
Western Blotting (WB) image for anti-FOXO1 antibody (Forkhead Box O1) (pSer319) (ABIN498786) Western blot (WB) analysis of p-FKHR/FOXO1A antibody in extracts from HeLa cells