anti-Human GSK3 alpha antibody for Immunohistochemistry

Recommended GSK3 alpha Antibody (supplied by: Log in to see )

Antigen
Glycogen Synthase Kinase 3 alpha (GSK3a) Antibodies
  • GSK3A
  • CG5182
  • Dmel\\CG5182
  • GSK3a
  • 2700086H06Rik
  • xgsk3
  • GSK-3[a]
  • GSK-3[b]
  • GSK3
  • gsk3a
  • glycogen synthase kinase 3 alpha
  • CG5182 gene product from transcript CG5182-RA
  • glycogen synthase kinase 3 alpha b
  • GSK3A
  • gsk3a
  • Bm1_31380
  • Pk34A
  • Gsk3a
  • LOC100339192
  • gsk3ab
Reactivity
Human
308
160
132
7
7
6
4
4
3
1
1
1
1
Host
Mouse
217
117
3
Clonality
Monoclonal
Conjugate
This GSK3 alpha antibody is un-conjugated
24
13
12
7
6
6
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
295
150
138
57
51
48
30
13
7
7
3
3
2
1
Options
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Catalog No. ABIN969179
$ 442.20
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.900302 ABIN1531854 IHC ELISA WB Rabbit IgG pSer21 Log in to see Polyclonal
8.900302 ABIN2707539 IC IF IP IHC WB Rabbit N-Term, pSer21 Log in to see Polyclonal
8.900302 ABIN1870216 IF IHC WB Rabbit IgG pSer21 Log in to see Polyclonal
8.900302 ABIN257307 ICC IF IHC IHC (p) IP WB Rabbit Log in to see Polyclonal
8.900302 ABIN2464059 IHC ELISA WB Mouse truncated Log in to see 6G2F1-6G2F2
8.900302 ABIN1843758 IHC ELISA WB Mouse Log in to see
8.900302 ABIN3019563 IF IHC WB Rabbit pSer21 Log in to see Polyclonal
8.900302 ABIN2426041 IHC ELISA Rabbit IgG Log in to see Polyclonal
8.900302 ABIN2431485 IHC ELISA Rabbit IgG Log in to see Polyclonal
8.900302 ABIN1847476 IP IHC ELISA WB Rabbit N-Term, pSer21 Log in to see Polyclonal
8.900302 ABIN1848108 IP IHC ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN1450608 IP IHC ELISA WB Rabbit IgG N-Term Log in to see Polyclonal 1
1 ABIN1872906 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN3184955 ELISA IHC IP WB Rabbit IgG Ser45 Log in to see Polyclonal
1 ABIN3182021 ELISA IHC IP WB Rabbit IgG pSer21 Log in to see Polyclonal
1 ABIN362496 IF IHC WB Rabbit IgG AA 19-23 Log in to see Polyclonal 4
1 ABIN361886 IF IHC WB Rabbit IgG pSer21 Log in to see Polyclonal 4
1 ABIN407681 IHC (p) IP IHC WB Rabbit N-Term Log in to see Polyclonal
1 ABIN3198103 IC IF IHC IP WB Rabbit N-Term Log in to see Polyclonal
1 ABIN1859082 ICC IHC IP WB Rabbit IgG AA 115-409 Log in to see Polyclonal

General

Antigen Glycogen Synthase Kinase 3 alpha (GSK3a) Antibodies
Reactivity Human
(308), (160), (132), (7), (7), (6), (4), (4), (3), (1), (1), (1), (1)
Host Mouse
(217), (117), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This GSK3 alpha antibody is un-conjugated
(24), (13), (12), (7), (6), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(295), (150), (138), (57), (51), (48), (30), (13), (7), (7), (3), (3), (2), (1)
Pubmed 3 references available
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Product Details anti-GSK3 alpha Antibody

Target Details GSK3 alpha Application Details Handling References for anti-GSK3 alpha antibody (ABIN969179) Images
Purification Ascites
Immunogen Purified recombinant fragment of GSK3 alpha expressed in E. coli.
Clone 6G2F1

Target Details GSK3 alpha

Product Details anti-GSK3 alpha Antibody Application Details Handling References for anti-GSK3 alpha antibody (ABIN969179) Images back to top
Antigen
Alternative Name GSK3 alpha (GSK3a Antibody Abstract)
Background GSK3 alpha (Glycogen synthase kinase 3 alpha), with 483-amino acid protein (about 53 kDa), belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily,GSK3 subsubfamily, which also includes GSK3 beta.GSK3 is a multifunctional serine/threonine kinase that is usually inactivated by serine phosphorylation in response to extracellular cues. GSK3 is a key regulator of numerous signalling pathways, including cellular responses to Wnt, receptor tyrosine kinases and G-protein-coupled receptors and is involved in a wide range of cellular processes, ranging from glycogen metabolism to cell cycle regulation and proliferation.GSK3 alpha is implicated in the control of several regulatory proteins including glycogen synthase and transcription factors.
Gene ID 2931
HGNC 2931
Research Area Cardiovascular, Hypertrophy, Atherosclerosis, Wnt, Kinases/Phosphatases
Pathways PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process

Application Details

Product Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Handling References for anti-GSK3 alpha antibody (ABIN969179) Images back to top
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only

Handling

Product Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Application Details References for anti-GSK3 alpha antibody (ABIN969179) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.

References for anti-GSK3 alpha antibody (ABIN969179)

Product Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Application Details Handling Images back to top
Product cited in:

Sayas, Ariaens, Ponsioen, Moolenaar: "GSK-3 is activated by the tyrosine kinase Pyk2 during LPA1-mediated neurite retraction." in: Molecular biology of the cell, Vol. 17, Issue 4, pp. 1834-44, 2006

Bradley, Currie, MacMillan, Muir, McCarron: "Cyclic ADP-ribose increases Ca2+ removal in smooth muscle." in: Journal of cell science, Vol. 116, Issue Pt 21, pp. 4291-306, 2003

Doble, Woodgett: "GSK-3: tricks of the trade for a multi-tasking kinase." in: Journal of cell science, Vol. 116, Issue Pt 7, pp. 1175-86, 2003

Images

Product Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Application Details Handling References for anti-GSK3 alpha antibody (ABIN969179) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Glycogen Synthase Kinase 3 alpha (GSK3a) antibody (ABIN969179) Figure 1: Immunohistochemical analysis of paraffin-embedded human lung carcinoma (lef...
Western Blotting (WB) image for anti-Glycogen Synthase Kinase 3 alpha (GSK3a) antibody (ABIN969179) Figure 2: Western blot analysis using GSK3 alpha mouse mAb against truncated GSK3 alp...