anti-Rat (Rattus) GSK3 alpha antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended GSK3 alpha Antibody (supplied by: Log in to see )

Antigen
Glycogen Synthase Kinase 3 alpha (GSK3a) Antibodies
  • GSK3A
  • CG5182
  • Dmel\\CG5182
  • GSK3a
  • 2700086H06Rik
  • xgsk3
  • GSK-3[a]
  • GSK-3[b]
  • GSK3
  • gsk3a
  • glycogen synthase kinase 3 alpha
  • CG5182 gene product from transcript CG5182-RA
  • glycogen synthase kinase 3 alpha b
  • GSK3A
  • gsk3a
  • Bm1_31380
  • Pk34A
  • Gsk3a
  • LOC100339192
  • gsk3ab
Epitope
AA 1-50, pSer21
68
36
25
14
11
9
7
7
6
5
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
304
159
131
7
7
6
4
4
3
1
1
1
1
Host
Rabbit
213
117
3
Clonality
Polyclonal
Conjugate
This GSK3 alpha antibody is un-conjugated
24
13
12
7
6
6
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
291
150
136
53
50
47
29
12
7
7
3
3
1
Options
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Catalog No. ABIN708116
$ 317.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN874843 IF (p) Alexa Fluor 350 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
1 ABIN874838 IF (p) Alexa Fluor 488 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
1 ABIN874841 IF (p) Alexa Fluor 555 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
1 ABIN874839 IF (p) Alexa Fluor 647 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
1 ABIN708119 IF (p) Cy3 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
1 ABIN708120 IF (p) Cy5 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
1 ABIN708121 IF (p) Cy5.5 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
1 ABIN708122 IF (p) Cy7 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
1 ABIN708123 IF (p) FITC Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
1 ABIN2814063 IF (p) Alexa Fluor 594 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
1 ABIN5004108 IF (p) Alexa Fluor 680 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
1 ABIN5004109 IF (p) Alexa Fluor 750 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal

Similar anti-GSK3 alpha Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 19 Antibodies 36 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 4 Antibodies
Flow Cytometry (FACS) 2 Antibodies 2 Antibodies
Immunochromatography (IC) 2 Antibodies 3 Antibodies
Immunocytochemistry (ICC) 5 Antibodies 5 Antibodies
Immunofluorescence (IF) 18 Antibodies 19 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 4 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 46 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 24 Antibodies
Immunoprecipitation (IP) 38 Antibodies
Western Blotting (WB) 109 Antibodies

General

Antigen Glycogen Synthase Kinase 3 alpha (GSK3a) Antibodies
Epitope AA 1-50, pSer21
(68), (36), (25), (14), (11), (9), (7), (7), (6), (5), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(304), (159), (131), (7), (7), (6), (4), (4), (3), (1), (1), (1), (1)
Host Rabbit
(213), (117), (3)
Clonality
Polyclonal
Conjugate This GSK3 alpha antibody is un-conjugated
(24), (13), (12), (7), (6), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(291), (150), (136), (53), (50), (47), (29), (12), (7), (7), (3), (3), (1)
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Product Details anti-GSK3 alpha Antibody

Target Details GSK3 alpha Application Details Handling Images
Specificity This phosphorylation site is homologous to that of Ser21 in Mouse and Rat.
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human GSK3 Alpha around the phosphorylation site of Ser21
Isotype IgG

Target Details GSK3 alpha

Product Details anti-GSK3 alpha Antibody Application Details Handling Images back to top
Antigen
Alternative Name Gsk3 alpha (GSK3a Antibody Abstract)
Background

Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth. Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation.

Synonyms: Glycogen synthase kinase-3 alpha, GSK-3 alpha, Serine/threonine-protein kinase GSK3A, GSK3A

Gene ID 2931
UniProt P49840
Research Area Kinases/Phosphatases, Atherosclerosis, Hypertrophy, Wnt, Cardiovascular
Pathways PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process

Application Details

Product Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Handling Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Application Details Handling back to top
Supplier Images
ELISA image for anti-GSK3 alpha antibody (Glycogen Synthase Kinase 3 alpha) (AA 1-50) (ABIN708116) Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:...
SDS-PAGE (SDS) image for anti-GSK3 alpha antibody (Glycogen Synthase Kinase 3 alpha) (AA 1-50) (ABIN708116) Lane 1: rat heart lysates Lane 2: rat brain lysates probed with Anti phospho-GSK3 Alp...
Immunohistochemistry (IHC) image for anti-GSK3 alpha antibody (Glycogen Synthase Kinase 3 alpha) (AA 1-50) (ABIN708116) Formalin-fixed and paraffin embedded rat brain labeled with Anti-phospho-GSK3 Alpha(S...