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anti-Rat (Rattus) GSK3 alpha antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended GSK3 alpha Antibody (supplied by: Log in to see )

Antigen
Glycogen Synthase Kinase 3 alpha (GSK3a) Antibodies
  • 2700086H06Rik
  • CG5182
  • Dmel\\CG5182
  • GSK-3[a]
  • GSK-3[b]
  • GSK3
  • GSK3A
  • GSK3a
  • gsk3a
  • xgsk3
Epitope
AA 1-50, pSer21
62
46
26
12
9
9
8
6
6
5
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
251
119
91
6
2
2
2
2
1
1
Host
Rabbit
205
76
3
Clonality
Polyclonal
Conjugate
This GSK3 alpha antibody is un-conjugated
20
11
10
6
6
6
4
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
228
117
114
37
34
24
10
10
6
3
3
1
Supplier
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Catalog No. ABIN708116
$ 291.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008808274 ABIN874838 IF (p) Alexa Fluor 488 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
0.0008808274 ABIN874839 IF (p) Alexa Fluor 647 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
0.0008808274 ABIN874841 IF (p) Alexa Fluor 555 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
0.0008808274 ABIN874843 IF (p) Alexa Fluor 350 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
0.0008808274 ABIN708119 IF (p) Cy3 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
0.0008808274 ABIN708120 IF (p) Cy5 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
0.0008808274 ABIN708121 IF (p) Cy5.5 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
0.0008808274 ABIN708122 IF (p) Cy7 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
0.0008808274 ABIN708123 IF (p) FITC Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal
0.0008808274 ABIN2814063 IF (p) Alexa Fluor 594 Rabbit IgG AA 1-50, pSer21 Log in to see Polyclonal

Similar anti-GSK3 alpha Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 16 Antibodies 33 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 3 Antibodies
Immunochromatography (IC) 2 Antibodies 3 Antibodies
Immunocytochemistry (ICC) 4 Antibodies 4 Antibodies
Immunofluorescence (IF) 16 Antibodies 17 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 38 Antibodies 56 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies
Immunoprecipitation (IP) 25 Antibodies
Western Blotting (WB) 75 Antibodies

General

Antigen Glycogen Synthase Kinase 3 alpha (GSK3a) Antibodies
Epitope AA 1-50, pSer21
(62), (46), (26), (12), (9), (9), (8), (6), (6), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(251), (119), (91), (6), (2), (2), (2), (2), (1), (1)
Host Rabbit
(205), (76), (3)
Clonality
Polyclonal
Conjugate This GSK3 alpha antibody is un-conjugated
(20), (11), (10), (6), (6), (6), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(228), (117), (114), (37), (34), (24), (10), (10), (6), (3), (3), (1)
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Product Details anti-GSK3 alpha Antibody

Target Details GSK3 alpha Application Details Handling Images
Specificity This phosphorylation site is homologous to that of Ser21 in Mouse and Rat.
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human GSK3 Alpha around the phosphorylation site of Ser21
Isotype IgG

Target Details GSK3 alpha

Product Details anti-GSK3 alpha Antibody Application Details Handling Images back to top
Antigen
Alternative Name Gsk3 alpha (GSK3a Antibody Abstract)
Background

Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth. Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation.


Synonyms: Glycogen synthase kinase-3 alpha, GSK-3 alpha, Serine/threonine-protein kinase GSK3A, GSK3A
Gene ID 2931
UniProt P49840
Pathways PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-GSK3 alpha Antibody Target Details GSK3 alpha Application Details Handling back to top
Supplier Images
ELISA image for anti-GSK3 alpha antibody (Glycogen Synthase Kinase 3 alpha) (AA 1-50) (ABIN708116) Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:...
SDS-PAGE (SDS) image for anti-GSK3 alpha antibody (Glycogen Synthase Kinase 3 alpha) (AA 1-50) (ABIN708116) Lane 1: rat heart lysates Lane 2: rat brain lysates probed with Anti phospho-GSK3 Alp...
Immunohistochemistry (IHC) image for anti-GSK3 alpha antibody (Glycogen Synthase Kinase 3 alpha) (AA 1-50) (ABIN708116) Formalin-fixed and paraffin embedded rat brain labeled with Anti-phospho-GSK3 Alpha(S...