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Browse our GSK3 alpha Proteins (GSK3a)

Full name:
Glycogen Synthase Kinase 3 alpha Proteins (GSK3a)
On www.antibodies-online.com are 12 Glycogen Synthase Kinase 3 alpha (GSK3a) Proteins from 8 different suppliers available. Additionally we are shipping GSK3 alpha Antibodies (307) and GSK3 alpha Kits (47) and many more products for this protein. A total of 376 GSK3 alpha products are currently listed.
Synonyms:
2700086H06Rik, CG5182, Dmel\\CG5182, GSK-3[a], GSK-3[b], GSK3, gsk3a, xgsk3
list all proteins Gene Name GeneID UniProt
GSK3a 2931 P49840
GSK3a 606496 Q2NL51
GSK3a 50686 P18265

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GSK3 alpha Proteins (GSK3a) by Origin

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Top referenced GSK3 alpha Proteins

  1. Human GSK3 alpha Protein expressed in Escherichia coli (E. coli) - ABIN411907 : Edwards: Neisseria gonorrhoeae survival during primary human cervical epithelial cell infection requires nitric oxide and is augmented by progesterone. in Infection and immunity 2010 (PubMed)

More Proteins for GSK3 alpha Interaction Partners

Human Glycogen Synthase Kinase 3 alpha (GSK3a) interaction partners

  1. demonstrated that GSK-3alpha is regulated by CREB (show CREB1 Proteins) in lung cancer and is required for the cell viability. These findings implicate CREB (show CREB1 Proteins)-GSK-3alpha axis as a novel therapeutic target for lung cancer treatment

  2. GSK3 acts through APC motifs R2 and B to regulate APC:Axin interactions, promoting high-throughput of betacatenin to destruction.

  3. reveals that GSK-3alpha- and GSK-3beta-regulated pathways can be responsible for stepwise transition to myelodysplastic syndromes and subsequent acute myeloid leukemia (show BCL11A Proteins)

  4. CHP3 (show TESC Proteins) functions as a novel negative regulator of cardiomyocyte hypertrophy via inhibition of GSK3alpha/beta phosphorylation.

  5. Elevated GSK3 protein kinase activity is associated with non-small cell lung carcinoma

  6. GSK3A is redundant with GSK3B in regulating drug-resistance and chemotherapy-induced necroptosis

  7. ER stress-PERK-GSK3alpha/beta signaling promotes proatherogenic macrophage lipid accumulation

  8. glycogen synthase kinase 3 alpha and beta activity is increased in foetal membranes after term and preterm labour

  9. TRAIL-induced apoptosis in pancreatic ductal adenocarcinoma cell lines is enhanced by pharmacological inhibition of glycogen synthase kinase-3 (GSK-3) or by shRNA-mediated depletion of either GSK-3alpha or GSK-3beta.

  10. Data indicate that autophagy inhibition promotes glycogen synthase kinase-(GSK3) inhibition-induced apoptosis.

Mouse (Murine) Glycogen Synthase Kinase 3 alpha (GSK3a) interaction partners

  1. reveals that GSK-3alpha- and GSK-3beta-regulated pathways can be responsible for stepwise transition to myelodysplastic syndromes and subsequent acute myeloid leukemia (show BCL11A Proteins)

  2. Gsk3 play a role in the maintenance of DNA methylation (show HELLS Proteins) at a majority of the imprinted loci in embryonic stem cells

  3. Sperm GSK3A is essential for male fertility.

  4. The absence of oocyte GSK3 isoforms in the periconceptional period does not alter fertility yet causes offspring cardiac hyperplasia, cardiovascular defects, and significant neonatal death.

  5. results support the model that GSK3 activity status is regulated by the circadian clock and that GSK3 feeds back to regulate the molecular clock amplitude in the suprachiasmatic nucleus

  6. Gsk3-deleted neurons expressing upper layer markers exhibited striking migration failure in all areas of the cortex.

  7. PI3K/AKT-mediated inhibitory phosphorylation of GSK3 limits the regenerative outcome after peripheral nerve injury.

  8. double-knockout embryonic stem cells, as well as GSK-3beta(-/-) mouse embryonic fibroblast cells in which GSK-3alpha was knocked down to demonstrate that both isoforms of GSK-3, GSK-3alpha and GSK-3beta, are required for antiviral immune response.

  9. ER stress-PERK-GSK3alpha/beta signaling promotes proatherogenic macrophage lipid accumulation

  10. The two isoforms of GSK-3 are essential integrators of multiple developmental signals that act to maintain normal mammary gland function and suppress tumorigenesis.

Cow (Bovine) Glycogen Synthase Kinase 3 alpha (GSK3a) interaction partners

  1. GSK3A serine phosphorylation was positively correlated with embryo development

  2. signal pathways converged on inhibitory phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation

Xenopus laevis Glycogen Synthase Kinase 3 alpha (GSK3a) interaction partners

  1. A mechanism whereby LRP6 (show LRP6 Proteins) stabilizes beta-catenin (show CTNNB1 Proteins) independently of Axin (show AXIN1 Proteins) degradation by directly inhibiting GSK3's phosphorylation of beta-catenin (show CTNNB1 Proteins), is identified.

Pig (Porcine) Glycogen Synthase Kinase 3 alpha (GSK3a) interaction partners

  1. we demonstrate that PKA, PKC (show FYN Proteins) and PI3K pathways crosstalk in porcine male germ cells to crucially regulate GSK3A phosphorylation which subsequently controls cell motility.

Zebrafish Glycogen Synthase Kinase 3 alpha (GSK3a) interaction partners

  1. lycogen synthase kinase-3 (GSK3) was identified as a substrate of protein kinase c delta (show PKCd Proteins) in breast cancer cells.

  2. GSK3alpha, but not GSK3beta, is necessary in cardiomyocyte survival

GSK3 alpha (GSK3a) Protein Profile

Protein Summary

This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.

Alternative names and synonyms associated with GSK3 alpha (GSK3a)

  • glycogen synthase kinase 3 alpha (GSK3A)
  • glycogen synthase kinase 3 alpha (gsk3a)
  • glycogen synthase kinase 3 alpha (Bm1_31380)
  • CG5182 gene product from transcript CG5182-RA (Pk34A)
  • glycogen synthase kinase 3 alpha (Gsk3a)
  • glycogen synthase kinase 3 alpha (LOC100339192)
  • glycogen synthase kinase 3 alpha b (gsk3ab)
  • 2700086H06Rik protein
  • CG5182 protein
  • Dmel\\CG5182 protein
  • GSK-3[a] protein
  • GSK-3[b] protein
  • GSK3 protein
  • gsk3a protein
  • xgsk3 protein

Protein level used designations for GSK3a

glycogen synthase kinase-3 alpha , glycogen synthase kinase 3 alpha , CG5182-PA , Pk34A-PA , GSK-3 alpha , serine/threonine-protein kinase GSK3A , FA , factor A

GENE ID SPECIES
707037 Macaca mulatta
100144645 Xenopus (Silurana) tropicalis
456071 Pan troglodytes
100601486 Nomascus leucogenys
6101168 Brugia malayi
34705 Drosophila melanogaster
2931 Homo sapiens
484476 Canis lupus familiaris
606496 Mus musculus
50686 Rattus norvegicus
536561 Bos taurus
398338 Xenopus laevis
100515208 Sus scrofa
100736092 Cavia porcellus
101102753 Ovis aries
100339192 Oryctolagus cuniculus
30664 Danio rerio
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