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Browse our anti-Hexokinase 2 (HK2) Antibodies

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anti-Hexokinase 2 Antibodies (HK2)
On are 173 Hexokinase 2 (HK2) Antibodies from 27 different suppliers available. Additionally we are shipping Hexokinase 2 Proteins (23) and Hexokinase 2 Kits (17) and many more products for this protein. A total of 220 Hexokinase 2 products are currently listed.
AI642394, ARABIDOPSIS THALIANA HEXOKINASE 2, ATHXK2, F6F22.11, F6F22_11, fi09d05, fi17h06, hexokinase-2, hexokinase 2, HK2, HKII, HXK2, wu:fi09d05, wu:fi17h06, wu:fi31b04, zgc:55926

Most Popular Reactivities for anti-Hexokinase 2 (HK2) Antibodies

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anti-Human Hexokinase 2 Antibodies:

anti-Mouse (Murine) Hexokinase 2 Antibodies:

anti-Rat (Rattus) Hexokinase 2 Antibodies:

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Top referenced anti-Hexokinase 2 Antibodies

  1. Human Polyclonal Hexokinase 2 Primary Antibody for WB - ABIN1882090 : Kuwabara, Ishikawa, Kobayashi, Kobayashi, Sugiyama: Renal clearance of a recombinant granulocyte colony-stimulating factor, nartograstim, in rats. in Pharmaceutical research 1996 (PubMed)
    Show all 5 references for ABIN1882090

  2. Human Polyclonal Hexokinase 2 Primary Antibody for EIA, IHC (p) - ABIN360640 : Laakso, Malkki, Deeb: Amino acid substitutions in hexokinase II among patients with NIDDM. in Diabetes 1995 (PubMed)
    Show all 5 references for ABIN360640

  3. Human Polyclonal Hexokinase 2 Primary Antibody for EIA, IHC (p) - ABIN360641 : Kiritsy, Antoniades, Carlson, Beaulieu, DAndrea, Lynch et al.: Combination of platelet-derived growth factor-BB and insulin-like growth factor-I is more effective than platelet-derived growth factor-BB alone in stimulating complete healing of full-thickness... in Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2006 (PubMed)
    Show all 5 references for ABIN360641

  4. Human Polyclonal Hexokinase 2 Primary Antibody for IHC (p), WB - ABIN392755 : Echwald, Bjørbaek, Hansen, Clausen, Vestergaard, Zierath, Printz, Granner, Pedersen: Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity. in Diabetes 1995 (PubMed)
    Show all 3 references for ABIN392755

  5. Human Monoclonal Hexokinase 2 Primary Antibody for FACS, IHC - ABIN969196 : Lim, Hao, Shaw, Patel, Szabó, Rual, Fisk, Li, Smolyar, Hill, Barabási, Vidal, Zoghbi: A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. in Cell 2006 (PubMed)
    Show all 3 references for ABIN969196

  6. Human Monoclonal Hexokinase 2 Primary Antibody for EIA, WB - ABIN263918 : Furuta, Nishi, Le Beau, Fernald, Yano, Bell: Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization. in Genomics 1997 (PubMed)
    Show all 2 references for ABIN263918

  7. Mouse (Murine) Polyclonal Hexokinase 2 Primary Antibody for IHC, WB - ABIN3021256 : Guo, Yao, Zhan, Hu, Yue, Cheng, Liu, Ye, Qing, Zhang, Liu: N-methylhemeanthidine chloride, a novel Amaryllidaceae alkaloid, inhibits pancreatic cancer cell proliferation via down-regulating AKT activation. in Toxicology and applied pharmacology 2014 (PubMed)

  8. Cow (Bovine) Polyclonal Hexokinase 2 Primary Antibody for IHC, WB - ABIN2774067 : Paudyal, Oriuchi, Paudyal, Higuchi, Nakajima, Endo: Expression of glucose transporters and hexokinase II in cholangiocellular carcinoma compared using [18F]-2-fluro-2-deoxy-D-glucose positron emission tomography. in Cancer science 2008 (PubMed)

More Antibodies against Hexokinase 2 Interaction Partners

Human Hexokinase 2 (HK2) interaction partners

  1. AKT (show AKT1 Antibodies) inhibition blocks miR (show MLXIP Antibodies)-124 silencing-induced AKT1 (show AKT1 Antibodies)/2, glucose transporter 1 (show SLC2A1 Antibodies), hexokinase II activation, cell proliferation, and glycolytic or energy metabolism changes. In summary, this study demonstrated that miR (show MLXIP Antibodies)-124 is able to inhibit proliferation, glycolysis, and energy metabolism, potentially by targeting AKT1 (show AKT1 Antibodies)/2-glucose transporter 1 (show SLC2A1 Antibodies)/hexokinase II in non-small cell lung cancer cells.

  2. Results from the simulations show that HK2 binding restricts the movement of the VDAC1 (show VDAC1 Antibodies) N-terminal helix. As a result, VDAC1 (show VDAC1 Antibodies) is kept in the open state most of the time and probably allows a constant supply of ATP to HK2 for glycolysis.

  3. These results suggest that HK2 plays important roles in the glycolytic, proliferation and migration properties of colorectal carcinoma

  4. High HK2 expression is associated with prostate cancer.

  5. We demonstrated that the expression levels of glycolysis-related proteins glucose transporter 1 (show SLC2A1 Antibodies), hexokinase II, carbonic anhydrase IX (show CA9 Antibodies), and monocarbonylate transporter 4 differ between thyroid cancer subtypes and are correlated with poorer prognosis

  6. miR (show MLXIP Antibodies)-181b directly inhibits the expression level of hexokinase 2 (HK2), a key enzyme that catalyzes the first step of glycolysis, through targeting its 3'-untranslated region.

  7. The N-terminal end of HKII has a mitochondrial-binding site and a VDAC bindig site.

  8. HK2 functions as a novel oncogene (show RAB1A Antibodies) in lung cancer and may be a potential therapeutic target for lung cancer.

  9. Cells with HKII knockdown showed no changes in 3BP sensitivity, suggesting the effects of 3BP are independent of HKII expression.

  10. Suggest HK2 as an independent prognostic indicator of radiation resistance in cervical squamous carcinoma.

Mouse (Murine) Hexokinase 2 (HK2) interaction partners

  1. Hexokinase expression is highly enriched in neurons compared to astrocytes.

  2. Hexokinase II (HKII) binding to the mitochondria is decreased in muscle from high fat diet-fed SIRT3 (show SIRT3 Antibodies) KO mice.

  3. HK2 is upregulated in prostate cancer cells harboring Pten (show PTEN Antibodies)/p53 (show TP53 Antibodies) mutations. HK2 is required for Pten (show PTEN Antibodies)-/p53 (show TP53 Antibodies)-deficiency-driven prostate tumor growth in vivo.

  4. A lack of effect on gene expression, changes in the protein expression patterns of the key genes GLUT1/SLC2A1 (show SLC2A1 Antibodies) and HK2 were observed after radiation treatment.

  5. Both HK2 mRNA and protein were increased under hypoxia, which is accompanied by an increase of glucose uptake and production of lactate.

  6. Suggest that HK2 attenuates cardiac hypertrophy by decreasing ROS (show ROS1 Antibodies) accumulation via increased pentose phosphate pathway flux.

  7. phosphorylation-mediated regulation of mitochondrial HK-II would be a critical component of the protective effect of Akt (show AKT1 Antibodies).

  8. Reduced muscle HKII protein content results in impaired muscle functionality during recovery from ischemic-reperfusion injury.

  9. HKII mitochondrial binding is also important for the hypertrophic effects, as HKII dissociation from the mitochondria resulted in de novo hypertrophy.

  10. We identified miR (show MLXIP Antibodies)-143 as an essential regulator of cancer glycolysis via targeting HK2.

Horse (Equine) Hexokinase 2 (HK2) interaction partners

  1. The tissue expression profiles of eGYS1, equine type II hexokinase (eHKII) and muscle-type phosphofructokinase (ePFKM) were determined by real-time PCR and western blot analysis.

Hexokinase 2 (HK2) Antigen Profile

Antigen Summary

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Alternative names and synonyms associated with Hexokinase 2 (HK2)

  • hexokinase 2 (HK2) antibody
  • hexokinase 2 (hk2) antibody
  • hexokinase 2 (Hk2) antibody
  • hexokinase 2 (HXK2) antibody
  • hexokinase-2-like (LOC100856448) antibody
  • similar to D.occidentalis hexokinase HXK which is able to phosphorylate glucose and fructose; similar to S. cerevisiae HXK2 (YGL253W) (HXK2) antibody
  • AI642394 antibody
  • ATHXK2 antibody
  • F6F22.11 antibody
  • F6F22_11 antibody
  • fi09d05 antibody
  • fi17h06 antibody
  • hexokinase-2 antibody
  • hexokinase 2 antibody
  • HK2 antibody
  • HKII antibody
  • HXK2 antibody
  • wu:fi09d05 antibody
  • wu:fi17h06 antibody
  • wu:fi31b04 antibody
  • zgc:55926 antibody

Protein level used designations for anti-Hexokinase 2 (HK2) Antibodies

hexokinase 2 , hexokinase-2-like , HK II , hexokinase type II , hexokinase-2 , hexokinase-2, muscle , muscle form hexokinase , hexokinase II , DrHXK2 , likely hexokinase II

741291 Pan troglodytes
100032849 Monodelphis domestica
100145699 Xenopus (Silurana) tropicalis
100396473 Callithrix jacchus
100460834 Pongo abelii
3099 Homo sapiens
100036846 Xenopus laevis
374044 Gallus gallus
494561 Sus scrofa
788926 Bos taurus
15277 Mus musculus
25059 Rattus norvegicus
475781 Canis lupus familiaris
100338214 Oryctolagus cuniculus
100732658 Cavia porcellus
406339 Danio rerio
100009677 Equus caballus
101107690 Ovis aries
816505 Arabidopsis thaliana
100856448 Canis lupus familiaris
3641015 Candida albicans SC5314
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