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anti-Human Huntingtin antibody for Immunohistochemistry

Recommended Huntingtin Antibody (supplied by: Log in to see )

Antigen
Huntingtin (HTT) Antibodies
  • HTT
  • hd
  • ZHD
  • CG9995
  • Dmel\\CG9995
  • HD
  • Hsap\\HD
  • Htt
  • dHtt
  • dhtt
  • SLC6A4
  • huntington
  • it15
  • htt
  • IT15
  • AI256365
  • C430023I11Rik
  • Hd
  • Hdh
  • solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • huntingtin
  • SLC6A4
  • LOC100216476
  • htt
  • Htt
  • HTT
  • HDH
Epitope
C-Term
14
12
12
7
7
5
5
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
148
99
58
13
6
2
2
2
1
1
1
Host
Rabbit
80
73
3
1
Clonality
Polyclonal
Conjugate
This Huntingtin antibody is un-conjugated
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
128
71
70
37
26
25
23
17
13
8
4
3
2
1
Supplier
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Catalog No. ABIN2470221
$ 515.63
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.037158 ABIN100604 IHC ELISA WB Rabbit IgG AA 416-424, pSer421 Log in to see Polyclonal
9.037158 ABIN2736926 IHC WB Rabbit IgG Log in to see Polyclonal
9.037158 ABIN2471198 IHC ELISA WB Mouse IgG2a kappa Log in to see 3F1
1 ABIN1450584 IHC ELISA Rabbit IgG N-Term Log in to see Polyclonal 3
1 ABIN4320700 ELISA ICC IF IHC WB Rabbit C-Term Log in to see Polyclonal 3
1 ABIN269392 IHC (fro) IP IHC WB Mouse IgG1 AA 2703-2911 Log in to see HDC8A4
1 ABIN269391 IHC (fro) IP IHC WB Mouse IgG1 Log in to see HDB4E10
1 ABIN153591 IHC (fro) IP IHC WB Mouse IgG1 Log in to see HDA3E10
1 ABIN252646 IHC IHC (fro) WB Mouse IgG Log in to see 1A771
1 ABIN3182875 ELISA IHC Rabbit IgG pSer421 Log in to see Polyclonal
1 ABIN3185117 ELISA IHC Rabbit IgG Ser47 Log in to see Polyclonal
1 ABIN4320701 ICC IF IHC IHC (p) Rabbit IgG Log in to see Polyclonal
1 ABIN1450323 IHC ELISA Rabbit IgG pSer421, N-Term Log in to see Polyclonal
1 ABIN4320703 IF IHC IHC (p) WB Mouse IgG Log in to see 4-13
1 ABIN4320699 ELISA ICC IF IHC WB Rabbit N-Term Log in to see Polyclonal
1 ABIN4320702 ELISA IF IHC IHC (p) WB Mouse IgG Log in to see 3-19
1 ABIN2741589 IF IHC WB Mouse IgG AA 544-552 Log in to see 4-13
1 ABIN790734 IHC WB Mouse IgG N-Term Log in to see H-F5
1 ABIN1607891 FM IHC ELISA WB Rabbit C-Term Log in to see Polyclonal
1 ABIN1607890 FM IHC ELISA WB Rabbit N-Term Log in to see Polyclonal

Top referenced anti-Huntingtin antibody for Immunohistochemistry

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Application / Reactivity Human
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Fluorescence Microscopy (FM) 2 Antibodies
Immunochromatography (IC) 8 Antibodies
Immunocytochemistry (ICC) 15 Antibodies
Immunofluorescence (IF) 22 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 67 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 35 Antibodies
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Western Blotting (WB) 120 Antibodies

General

Antigen Huntingtin (HTT) Antibodies
Epitope C-Term
(14), (12), (12), (7), (7), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(148), (99), (58), (13), (6), (2), (2), (2), (1), (1), (1)
Host Rabbit
(80), (73), (3), (1)
Clonality
Polyclonal
Conjugate This Huntingtin antibody is un-conjugated
(2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(128), (71), (70), (37), (26), (25), (23), (17), (13), (8), (4), (3), (2), (1)
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Product Details anti-Huntingtin Antibody

Target Details Huntingtin Application Details Handling Images
Specificity PSer421
Purification Immunoaffinity Chromatography
Immunogen Huntingtin antibody was raised against amino acids 416-424 from the C-Terminus of Huntingtin (Human).

Target Details Huntingtin

Product Details anti-Huntingtin Antibody Application Details Handling Images back to top
Antigen
Alternative Name Huntingtin (HTT Antibody Abstract)
Background Huntingtin (also known as Huntington's disease protein, Htt and HD protein) is the protein product of a disease gene linked to Huntington's disease, a neuro-degenerative disorder characterized by loss of striatal neurons. This may be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product (see partial protein sequence below). The huntingtin gene locus is large, spanning 180 kb and consisting of 67 exons. It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues. The genetic defect leading to Huntington's disease may not necessarily eliminate transcription, but may confer a new property on the mRNA or alter the function of the protein. One candidate is the huntingtin-associated protein-1, highly expressed in brain, which has increased affinity for huntingtin protein with expanded polyglutamine repeats. Normal huntingtin protein shows a cytoplasmic localization. This protein is widely expressed with the highest level of expression in the brain (nerve fibers, varicosities, and nerve endings). In the brain, the regions where it can be mainly found are the cerebellar cortex, the neocortex, the striatum, and the hippocampal formation.
Gene ID 3064
UniProt P42858
Research Area Neurology, Virology
Pathways PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport

Application Details

Product Details anti-Huntingtin Antibody Target Details Huntingtin Handling Images back to top
Application Notes Huntingtin antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 1:500, immunofluorescence, and immunoprecipitation.
Restrictions For Research Use only

Handling

Product Details anti-Huntingtin Antibody Target Details Huntingtin Application Details Images back to top
Format Liquid
Buffer 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice As with all antibodies avoid freeze/thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Store Huntingtin antibody at 4 °C or -20 °C.

Images

Product Details anti-Huntingtin Antibody Target Details Huntingtin Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Huntingtin antibody (HTT) (C-Term) (ABIN2470221) anti-Huntingtin (HTT) (C-Term) antibody