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Browse our LAMTOR2 Proteins (LAMTOR2)

Full name:
Late Endosomal/lysosomal Adaptor, MAPK and MTOR Activator 2 Proteins (LAMTOR2)
On www.antibodies-online.com are 14 Late Endosomal/lysosomal Adaptor, MAPK and MTOR Activator 2 (LAMTOR2) Proteins from 7 different suppliers available. Additionally we are shipping LAMTOR2 Antibodies (36) and many more products for this protein. A total of 53 LAMTOR2 products are currently listed.
Synonyms:
2010111E04Rik, AL022628, ENDAP, HSPC003, mapbpip, MAPKSP1AP, P14, Rab25, Ragulator2, RGD1562501, robld3, zgc:100811
list all proteins Gene Name GeneID UniProt
LAMTOR2 28956 Q9Y2Q5
LAMTOR2 83409 Q9JHS3
Rat LAMTOR2 LAMTOR2 295234  

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LAMTOR2 Proteins (LAMTOR2) by Origin

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Top referenced LAMTOR2 Proteins

  1. Human LAMTOR2 Protein expressed in Escherichia coli (E. coli) - ABIN2005287 : Schröder, Wrocklage, Pan, Jäger, Kösters, Schäfer, Elsässer, Mann, Hasilik: Integral and associated lysosomal membrane proteins. in Traffic (Copenhagen, Denmark) 2007 (PubMed)
    Show all 3 references for ABIN2005287

  2. Human LAMTOR2 Protein expressed in Escherichia coli (E. coli) - ABIN667853 : Waters, Marchbank, Solomon, Whitehouse, Gautel: Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover. in FEBS letters 2009 (PubMed)
    Show all 2 references for ABIN667853

More Proteins for LAMTOR2 Interaction Partners

Human Late Endosomal/lysosomal Adaptor, MAPK and MTOR Activator 2 (LAMTOR2) interaction partners

  1. identified polymorphisms in LAMTOR2 and LAMTOR3 (show MAPKSP1 Proteins) do not seem to play a relevant role in breast cancer

  2. The ROBLD3 C-A, thorn23 mutation creates a 50SS capable of recruiting an inhibitory U1 snRNP complex leading to a failure of proper 30 end formation and rapid degradation of p14 mRNA.

  3. simulations constitute a multi-dimensional exploration of how EGF (show EGF Proteins)-dependent EGFR (show EGFR Proteins) endocytosis and ERK (show EPHB2 Proteins) activation are dynamically affected by scaffolds KSR (show KSR1 Proteins) and MP1 (show PITRM1 Proteins), co-regulated by Cbl (show CBL Proteins)-CIN85 (show SH3KBP1 Proteins) and Endophilin A1 (show SH3G2 Proteins)

  4. A complex encoded by the MAPKSP1 (show MAPKSP1 Proteins), ROBLD3, and c11orf59 (show LAMTOR1 Proteins) genes interacts with the Rag GTPases, recruits them to lysosomes, and is essential for mTORC1 activation

Mouse (Murine) Late Endosomal/lysosomal Adaptor, MAPK and MTOR Activator 2 (LAMTOR2) interaction partners

  1. Hotair silence activates P16(Ink4a) and P14(ARF) signaling by enhancing miR-218 expression and suppressing Bmi-1 expression, resulting in the suppression of tumorigenesis in HCC.

  2. LAMTOR2 has a role in regulating dendritic cell homeostasis through FLT3 (show FLT3 Proteins)-dependent mTOR (show FRAP1 Proteins) signalling

  3. Lamtor2 deficiency affects TGFbeta1 (show TGFB1 Proteins) sensitivity of Langerhan cells, which is mandatory for their homeostasis and subsequently for their immunological function during contact hypersensitivity.

  4. We show an essential function for late endosomes carrying the p14 (show PCOLCE Proteins)-MP1 (show MAPKSP1 Proteins) (LAMTOR2/3) complex in focal adhesion dynamics.

  5. The late endosomal adaptor molecule p14 (LAMTOR2) represents a novel regulator of Langerhans cell homeostasis.

  6. Data indicate that LAMTOR3 (show MAPKSP1 Proteins) protein is stabilized by associating with LAMTOR2.

  7. The late endosomal adaptor p14 (show PCOLCE Proteins) (also known as LAMTOR2) is one of the components for cellular host defense against the intracellular pathogen Salmonella enterica serovar Typhimurium.

  8. analysis of interactions between kinase scaffold MP1 (show MAPKSP1 Proteins)/p14 (show PCOLCE Proteins) and its endosomal anchoring protein p18 (show CDKN2C Proteins)

  9. A combination of cell fractionation, two-dimensional gel electrophoresis and mass spectrometry revealed 31 proteins differentially regulated in p14/ organelles, which were rescued by reexpression of pEGFP-p14 in p14/ endosomes

  10. spatial regulation of MAPK signaling, illustrating how p14 and MP1 collaborate as an endosomal adaptor/scaffold complex

LAMTOR2 Protein Profile

Protein Summary

The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with LAMTOR2

  • late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 (LAMTOR2)
  • late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 (Lamtor2)
  • late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 (lamtor2)
  • 2010111E04Rik protein
  • AL022628 protein
  • ENDAP protein
  • HSPC003 protein
  • mapbpip protein
  • MAPKSP1AP protein
  • P14 protein
  • Rab25 protein
  • Ragulator2 protein
  • RGD1562501 protein
  • robld3 protein
  • zgc:100811 protein

Protein level used designations for LAMTOR2

MAPKSP1 adaptor protein , endosomal adaptor protein p14 , late endosomal/lysosomal Mp1-interacting protein , late endosomal/lysosomal adaptor and MAPK and MTOR activator 2 , mitogen-activated protein-binding protein-interacting protein (MAPBPIP) , ragulator complex protein LAMTOR2 , roadblock domain containing 3 , roadblock domain-containing protein 3 , mitogen-activated protein-binding protein-interacting protein , late endosomal/lysosomal MP1 interacting protein , mitogen activated protein binding protein interacting protein , mitogen-activated protein binding protein interacting protein , Mitogen-activated protein-binding protein-interacting protein , Roadblock domain-containing protein 3 , putative mitogen-activated protein-binding protein-interacting protein

GENE ID SPECIES
28956 Homo sapiens
616375 Bos taurus
83409 Mus musculus
445155 Danio rerio
100190214 Taeniopygia guttata
480125 Canis lupus familiaris
295234 Rattus norvegicus
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