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anti-Rat (Rattus) MAPKAP1 antibody for ELISA

Recommended MAPKAP1 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Antibodies
  • AI591529
  • CG10105
  • D230039K05Rik
  • Dmel\\CG10105
  • dSin1
  • im:7143088
  • JC310
  • MAPKAP1
  • MGC53034
  • MIP1
  • mip1
  • si:ch73-242f23.1
  • sin1
  • SIN1
  • Sin1
  • sin1b
  • SIN1b
  • sin1g
  • SIN1g
Epitope
Internal Region
23
15
8
4
4
4
2
2
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
76
27
23
3
2
Host
Rabbit
79
Clonality
Polyclonal
Conjugate
This MAPKAP1 antibody is un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
68
32
31
11
10
3
2
1
1
1
1
1
Supplier
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Catalog No. ABIN1002803
$ 455.07
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0012131304 ABIN1002804 IHC ELISA WB Rabbit IgG N-Term Log in to see Polyclonal 4
0.0012131304 ABIN2448675 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal
0.0012131304 ABIN1030995 IHC ELISA WB Rabbit Middle Region Log in to see Polyclonal
0.0012131304 ABIN1031450 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal
0.0012131304 ABIN1088841 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0012131304 ABIN1088842 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0012131304 ABIN2448674 IHC ELISA WB Rabbit Log in to see Polyclonal
0.0012131304 ABIN1887685 IHC ELISA WB Rabbit Center Log in to see Polyclonal
0.0012131304 ABIN1888099 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal
0.0012131304 ABIN1584754 IHC ELISA WB Rabbit Log in to see Polyclonal
0.0012131304 ABIN1584753 IHC ELISA WB Rabbit Log in to see Polyclonal

Top referenced anti-MAPKAP1 antibody for ELISA

Similar anti-MAPKAP1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 12 Antibodies 12 Antibodies 33 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 2 Antibodies 2 Antibodies
Immunofluorescence (IF) 5 Antibodies 6 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 17 Antibodies 18 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies 5 Antibodies
Western Blotting (WB) 23 Antibodies 28 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies

General

Antigen Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Antibodies
Epitope Internal Region
(23), (15), (8), (4), (4), (4), (2), (2), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(76), (27), (23), (3), (2)
Host Rabbit
(79)
Clonality
Polyclonal
Conjugate This MAPKAP1 antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(68), (32), (31), (11), (10), (3), (2), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-MAPKAP1 Antibody

Target Details MAPKAP1 Application Details Handling References for anti-MAPKAP1 Antibody (ABIN1002803) Images
Blocking Peptide Blocking peptide for this product available: ABIN1003959
Purification Affinity chromatography purified via peptide column.
Immunogen MAPKAP1 antibody was raised in rabbits against an 18 amino acid peptide from near the center of human MAPKAP1.
Isotype IgG

Target Details MAPKAP1

Product Details anti-MAPKAP1 Antibody Application Details Handling References for anti-MAPKAP1 Antibody (ABIN1002803) Images back to top
Antigen
Alternative Name MAPKAP1 (MAPKAP1 Antibody Abstract)
Background MAPKAP1 was initially identified as the human homolog of S. pombe SIN1. Recent evidence has shown that it identical to Mip1, a protein that interacts with MEKK2, a member of the mitogen-activated protein kinase (MAPK) intracellular signaling network. MAPKAP1 is thought to prevent MEKK2 activation and dimerization by forming a complex with the inactive and non-phosphorylated MEKK2, thereby blocking the JNK1/2, ERK1/2, p38 and ERK5 MAPKs. MAPKAP1 has also been shown to play a role in the TOR signaling process, a pathway that is involved in controlling cell growth and proliferation in response to environmental cues such as nutrients, growth factors and hormones. Experiments showed that MAPKAP1 helped to maintain the TOR/rictor assembly but not the TOR/RAPTOR complex, which allowed specific phosphorylation of Akt, a kinase that is believed to couple the growth factor-PI3K signaling pathway to the nutrient-regulated TOR signaling pathway. Multiple alternatively spliced isoforms of MAPKAP1 have been identified.
Pathways PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-MAPKAP1 Antibody Target Details MAPKAP1 Handling References for anti-MAPKAP1 Antibody (ABIN1002803) Images back to top
Application Notes MAPKAP1 antibody can be used for detection of MAPKAP1 by Western blot at 1 – 2 µg/ml. (Optimal dilution should be determined by user). Antibody can also be used for immunohistochemistry and ELISA and might be suited for other applications not tested so far.
Restrictions For Research Use only

Handling

Product Details anti-MAPKAP1 Antibody Target Details MAPKAP1 Application Details References for anti-MAPKAP1 Antibody (ABIN1002803) Images back to top
Format Liquid
Buffer Antibody is supplied in PBS containing 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
Storage 4 °C
Expiry Date 12 months

References for anti-MAPKAP1 Antibody (ABIN1002803)

Product Details anti-MAPKAP1 Antibody Target Details MAPKAP1 Application Details Handling Images back to top
Product cited in:

Jacinto, Facchinetti, Liu, Soto, Wei, Jung, Huang, Qin, Su: "SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity." in: Cell, Vol. 127, Issue 1, pp. 125-37, 2006

Wullschleger, Loewith, Hall: "TOR signaling in growth and metabolism." in: Cell, Vol. 124, Issue 3, pp. 471-84, 2006

Cheng, Zhang, Kim, Zhao, Zhao, Su: "Mip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation." in: Molecular and cellular biology, Vol. 25, Issue 14, pp. 5955-64, 2005

Schroder, Cloonan, Bushell, Sculley: "Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene." in: Gene, Vol. 339, pp. 17-23, 2004