Browse our anti-MTOR (FRAP1) Antibodies

Full name:
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) Antibodies (FRAP1)
On www.antibodies-online.com are 349 Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antibodies from 36 different suppliers available. Additionally we are shipping MTOR Kits (41) and MTOR Proteins (4) and many more products for this protein. A total of 409 MTOR products are currently listed.
Synonyms:
2610315D21Rik, AI327068, flat, FRAP, frap1, FRAP2, RAFT1, RAPT1, tor, wu:fc22h08
list all antibodies Gene Name GeneID UniProt
FRAP1 2475 P42345
FRAP1 56717 Q9JLN9
FRAP1 56718 P42346

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All available anti-MTOR Antibodies

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Top referenced anti-MTOR Antibodies

  1. Human Polyclonal MTOR Primary Antibody for EIA, IHC (p) - ABIN117909 : Chase, Rao, Hofmann, Chang-Hasnain: 1550 nm high contrast grating VCSEL. in Optics express 2010 (PubMed)
    Show all 9 references for 117909

  2. Dog (Canine) Polyclonal MTOR Primary Antibody for EIA, WB - ABIN401320 : McMahon, Choi, Lin, Abraham, Lawrence: The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin. in Molecular and cellular biology 2002 (PubMed)
    Show all 6 references for 401320

  3. Chicken Monoclonal MTOR Primary Antibody for IF, WB - ABIN968383 : Alarcon, Cardenas, Heitman: Mammalian RAFT1 kinase domain provides rapamycin-sensitive TOR function in yeast. in Genes & development 1996 (PubMed)
    Show all 5 references for 968383

  4. Human Polyclonal MTOR Primary Antibody for IF, IHC (p) - ABIN196962 : Holz, Blenis: Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase. in The Journal of biological chemistry 2005 (PubMed)
    Show all 4 references for 196962

  5. Human Polyclonal MTOR Primary Antibody for IF (p), IHC (p) - ABIN676403 : Li, Liu, Wang, Sun, Ding, Sun, Han, Wang: Follistatin could promote the proliferation of duck primary myoblasts by activating PI3K/Akt/mTOR signalling. in Bioscience reports 2014 (PubMed)
    Show all 4 references for 676403

  6. Human Polyclonal MTOR Primary Antibody for ELISA, WB - ABIN1531715 : Brown, Albers, Shin, Ichikawa, Keith, Lane, Schreiber: A mammalian protein targeted by G1-arresting rapamycin-receptor complex. in Nature 1994 (PubMed)
    Show all 3 references for 1531715

  7. Human Polyclonal MTOR Primary Antibody for ELISA, WB - ABIN1532744 : Onyango, Lubyova, Gardellin, Kurzbauer, Weith: Molecular cloning and expression analysis of five novel genes in chromosome 1p36. in Genomics 1998 (PubMed)
    Show all 3 references for 1532744

  8. Human Polyclonal MTOR Primary Antibody for IF (p), IHC (p) - ABIN747158 : Yang, Wang, Wang, Zhang, Zhang, Lu, Wang: mTOR is involved in 17?-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1, and CCNE1. in Molecular reproduction and development 2015 (PubMed)
    Show all 2 references for 747158

  9. Human Polyclonal MTOR Primary Antibody for IF, IHC (p) - ABIN390217 : Cao, Dong, Meng, Liu, Liao, Liu: MiR-511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3. in Tumour biology 2015 (PubMed)

  10. Human Polyclonal MTOR Primary Antibody for IHC, ELISA - ABIN1531910 : Luo, Yoneda, Ohmori, Sasaki, Shimbo, Eto, Kato, Miyano, Kobayashi, Sasahira, Chihara, Kuniyasu: Cancer usurps skeletal muscle as an energy repository. in Cancer research 2014 (PubMed)

More Antibodies against MTOR Interaction Partners

Horse (Equine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

Human Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. The simultaneous inhibition of the mTOR and MAPK (show MAPK1 Antibodies) pathways with Gnetin-C induces apoptosis in acute myeloid leukemia (show BCL11A Antibodies) cells.

  2. Data show that acquired immunodeficiency syndrome (AIDS) related diffuse large B-cell lymphoma (AR-DLBCL) frequently contain phosphorylated 70 ribosomal S6 protein-kinase (show CDK7 Antibodies) (p70S6K (show RPS6KB1 Antibodies)), a main downstream effector of the mTOR serine-threonine kinases (mTOR) pathway, and the presence of p70S6K (show RPS6KB1 Antibodies) is positively correlated with phosphorylated phosphatase and tensin homolog (show PTEN Antibodies) (pPTEN).

  3. Studies indicate that understanding mTOR network circuitry will provide insight into its deregulation in diabetes, cancer, and cardiovascular disease, but modeling in silico to elucidate how insulin (show INS Antibodies) activates mTORC2 (show CRTC2 Antibodies) remains poorly defined.

  4. Taken together, MREG (show MREG Antibodies) regulates thyroid cancer cell invasion and proliferation through PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)-mTOR signaling pathway. MREG (show MREG Antibodies) may serve as a promising therapeutic strategy for thyroid cancer.

  5. The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma.

  6. elevated serum and cellular levels of mTOR in the IGT group and FOXO-1 (show FOXO1 Antibodies) in IFG (show IFNG Antibodies) and IGT groups may be triggered by increased glucose concentration. Indeed, mTOR-mediated variations in cellular level from female patients and FOXO-1 (show FOXO1 Antibodies)-mediated variations of male patients indicated that these factors might play a critical role in glucose intolerance.

  7. Prospective studies are warranted to examine the association between p-mTOR expression and survival outcomes in breast carcinoma

  8. PKI-587 selectively abrogated PI3K (show PIK3CA Antibodies)/mTOR signaling in T-cell acute lymphoblastic leukemia, reducing tumor volume and enhancing survival in mouse xenograft model.

  9. Anti-tumor activity of selective exportin 1 (show XPO1 Antibodies) inhibitors is enhanced in non-Hodgkin lymphoma through combination with mTOR inhibitor and dexamethasone.

  10. High mTOR expression is associated with glioma.

Mouse (Murine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. We provide mechanistic evidence that S6K1 (show RPS6KB1 Antibodies)'s negative feedback to PI3K signaling is involved in axon growth inhibition, and show that phosphorylation of S6K1 (show RPS6KB1 Antibodies) is a more appropriate regeneration indicator than is S6 phosphorylation.

  2. study found that mTOR is highly activated during the pro- and pre-B stages of mouse B cell development.

  3. It is well accepted that myelin is a biologically active membrane in active communication with the axons. However, the axonal signals, the receptors on myelin, and the integration of intracellular signaling pathways emanating downstream from these receptors that drive the growth of the myelin sheath remain poorly understood in the CNS. This study brings up the intriguing possibility that FGF receptor (show FGFR2 Antibodies) 2, in the oligodendr

  4. Promoting amino acid sensitivity of the mTOR pathway is dependent on p62 accumulation by inhibition of autophagy and this process plays an important role in the hepatic differentiation of stem/progenitor cells.

  5. Inhibition of the mTOR pathway in abdominal aortic aneurysm preserves/restores the smooth muscle cell contractile phenotype and reduces inflammation.

  6. findings reveal an important role for mTOR signaling in maintaining CD4 (show CD4 Antibodies)(+)Foxp3 (show FOXP3 Antibodies)(+) regulatory T cells activity after adoptive transfer

  7. these studies demonstrate that mTORC2 (show CRTC2 Antibodies) in thymic epithelial cells is important for normal thymopoiesis and efficient T cell generation

  8. mitochondrial dysfunction triggers LKB1 (show STK11 Antibodies)-mediated AMPK (show PRKAA1 Antibodies) activation, which stimulates Sirt2 (show SIRT2 Antibodies) phosphorylation, leading to activation of mTOR-RAPTOR (show RPTOR Antibodies) and Glut1 (show SLC2A1 Antibodies)-mediated glucose uptake.

  9. We hypothesized that loss of Th17 cells via CD4 (show CD4 Antibodies)-specific deletion of mTORC1 activity would abrogate the development of bleomycin-induced pulmonary fibrosis. However, in actuality loss of Th17 cells led to increased mortality and fibrosis in response to bleomycin.

  10. oocyte suppression of Ddit4l (show DDIT4L Antibodies) expression allows for MTOR activation in cumulus cells.

Zebrafish Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. This study reveals the dramatic rescue effects of L-leucine stimulation of mTORC1 in RBS (show ESCO2 Antibodies) cells and supports that normal gene expression and translation requires ESCO2 (show ESCO2 Antibodies) function.

  2. By inhibiting mTOR signaling via Fbxw7 (show FBXW7 Antibodies), the amount of myelination during development is reduced.

  3. Apc mutations activate mechanistic target of rapamycin complex 1 in mice and zebrafish

  4. In our zebrafish model, autophagy induction does not depend on inhibition of the Tor pathway or activation of Tp53 (show TP53 Antibodies).

  5. TOR signaling is a common pathological pathway that can be leveraged for therapeutic benefits in cardiomyopathies of different origins.

  6. in addition to regulating cell growth and proliferation, TOR signaling controls the developmental program guiding epithelial morphogenesis in the intestine

Pig (Porcine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (show AKT1 Antibodies)-mTOR-FOXO1 (show FOXO1 Antibodies) signaling and suppressing the activation of TLR4 (show TLR4 Antibodies) and/or NOD2 (show NOD2 Antibodies) signaling pathways.

  2. Data show that the amount of proteins related to mechanistic target of rapamycin (mTOR) signaling pathways decreased along crypt-villus axis (CVA).

  3. AMPK (show PRKAA1 Antibodies)-mTOR-autophagy signaling is altered by intrauterine growth restriction in newborn piglets.

  4. Uroguanylin (show GUCA2B Antibodies) modulates (Na++K+)ATPase (show ATP1A1 Antibodies) in a proximal tubule cells via cGMP/protein kinase (show CDK7 Antibodies) G, cAMP/protein kinase A, and mTOR pathways.

  5. mTOR is involved in 17beta-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1 (show CCND1 Antibodies), and CCNE1 (show CCNE1 Antibodies).

  6. L-Glutamine (show GFPT2 Antibodies) enhances enterocyte growth via activation of the mTOR.

  7. Arg, Leu, and Gln act coordinately to stimulate proliferation of pTr (show PTCHD3 Antibodies) cells through activation of the MTOR-RPS6K-RPS6 (show RPS6 Antibodies)-EIF4EBP1 (show EIF4EBP1 Antibodies) signal transduction pathway.

  8. Data indicate that the expression of MAP1LC3A (show MAP1LC3A Antibodies), B and autophagy-associated genes (ATG5 (show ATG5 Antibodies), mTOR, Beclin-1 (show BECN1 Antibodies)) was increased in normal pigs, while decreased in miniature pigs.

  9. Biochemical, cellular, and molecular data suggest that L-arginine (show GATM Antibodies) stimulates mTOR biosynthesis, mTOR signaling, and overall protein biosynthesis/turnover in placental/trophoblast and blastocyst/ectoderm cells thereby enhancing cell proliferation.

  10. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK (show PRKAA1 Antibodies)/ERK (show MAPK1 Antibodies)/TSC2 (show TSC2 Antibodies)/mTOR signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

Cow (Bovine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. These findings suggest that mTOR is involved in the control of the expression of multiple genes in cattle, which may be triggered by the luteinizing hormone surge.

  2. 14-3-3gamma (show YWHAG Antibodies) affects mTOR protein pathway and regulates lactogenesis in dairy cow mammary epithelial cells.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2 (show JAK2 Antibodies)-STAT5 (show STAT5A Antibodies) and mTOR signaling pathways.

  4. Insulin (show INS Antibodies)-induced activation of phosphoinositide 3-kinase~mTOR pathway up-regulates tau protein via acceleration of protein synthesis in adrenal chromaffin cells, promoting neurite-like process outgrowth.

  5. IGF-I (show IGF1 Antibodies) down-regulated functional IGF-I receptor (show IGF1R Antibodies) via GSK-3beta (show GSK3b Antibodies) inhibition and mTOR activation; constitutive activity of GSK-3beta (show GSK3b Antibodies) maintained IGF-I receptor (show IGF1R Antibodies) level in nonstimulated cells.

  6. stimulation of mammary protein synthesis by amino acids and its enhancement by a combination of the lactogenic hormones hydrocortisone, insulin (show INS Antibodies), and prolactin (show PRL Antibodies) were associated with increased phosphorylation of the mTOR substrates

  7. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (show AKT1 Antibodies), mTOR, p70S6K (show RPS6KB1 Antibodies), and ERK1/2 (show MAPK1/3 Antibodies).

  8. prostaglandin F2alpha phosphorylates TSC2 (show TSC2 Antibodies) and activates mTOR and ribosomal protein S6 (show RPS6 Antibodies) kinase (show RPS6KB1 Antibodies) signaling in an AKT (show AKT1 Antibodies)-independent manner

  9. mTOR links IGF-I (show IGF1 Antibodies) and EGF (show EGF Antibodies) signaling in inhibiting the autophagy pathways.

MTOR (FRAP1) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Alternative names and synonyms associated with MTOR (FRAP1)

  • mechanistic target of rapamycin (serine/threonine kinase) (MTOR) antibody
  • mechanistic target of rapamycin (serine/threonine kinase) (Mtor) antibody
  • mechanistic target of rapamycin (serine/threonine kinase) (mtor) antibody
  • 2610315D21Rik antibody
  • AI327068 antibody
  • flat antibody
  • FRAP antibody
  • frap1 antibody
  • FRAP2 antibody
  • RAFT1 antibody
  • RAPT1 antibody
  • tor antibody
  • wu:fc22h08 antibody

Protein level used designations for FRAP1

FK506 binding protein 12-rapamycin associated protein 1 , FK506 binding protein 12-rapamycin associated protein 2 , FK506-binding protein 12-rapamycin complex-associated protein 1 , FKBP-rapamycin associated protein , FKBP12-rapamycin complex-associated protein 1 , mammalian target of rapamycin , rapamycin and FKBP12 target 1 , rapamycin associated protein FRAP2 , rapamycin target protein 1 , serine/threonine-protein kinase mTOR , FKBP-rapamycin associated protein (FRAP) , FKBP-rapamycin-associated protein FRAP , FKBP12-rapamycin complex-associated protein , angiopoietin-like factor CDT6 , RAPT1 , rapamycin and FKBP12 target-1 protein , target of rapamycin

GENE ID SPECIES
100051341 Equus caballus
419455 Gallus gallus
2475 Homo sapiens
56717 Mus musculus
56718 Rattus norvegicus
324254 Danio rerio
478232 Canis lupus familiaris
100127359 Sus scrofa
100139219 Bos taurus
100860902 Capra hircus
100271659 Ovis aries
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