Browse our anti-MTOR (FRAP1) Antibodies

Full name:
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) Antibodies (FRAP1)
On www.antibodies-online.com are 368 Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antibodies from 37 different suppliers available. Additionally we are shipping MTOR Kits (45) and MTOR Proteins (4) and many more products for this protein. A total of 432 MTOR products are currently listed.
Synonyms:
2610315D21Rik, AI327068, flat, FRAP, frap1, FRAP2, RAFT1, RAPT1, tor, wu:fc22h08
list all antibodies Gene Name GeneID UniProt
FRAP1 2475 P42345
FRAP1 56717 Q9JLN9
FRAP1 56718 P42346

Show all species

Show all synonyms

All available anti-MTOR Antibodies

Go to our pre-filtered search.

Top referenced anti-MTOR Antibodies

  1. Human Polyclonal MTOR Primary Antibody for EIA, IHC (p) - ABIN117909 : Chase, Rao, Hofmann, Chang-Hasnain: 1550 nm high contrast grating VCSEL. in Optics express 2010 (PubMed)
    Show all 9 references for 117909

  2. Dog (Canine) Polyclonal MTOR Primary Antibody for EIA, WB - ABIN401320 : McMahon, Choi, Lin, Abraham, Lawrence: The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin. in Molecular and cellular biology 2002 (PubMed)
    Show all 6 references for 401320

  3. Chicken Monoclonal MTOR Primary Antibody for IF, WB - ABIN968383 : Alarcon, Cardenas, Heitman: Mammalian RAFT1 kinase domain provides rapamycin-sensitive TOR function in yeast. in Genes & development 1996 (PubMed)
    Show all 5 references for 968383

  4. Human Polyclonal MTOR Primary Antibody for IF (p), IHC (p) - ABIN676403 : Li, Liu, Wang, Sun, Ding, Sun, Han, Wang: Follistatin could promote the proliferation of duck primary myoblasts by activating PI3K/Akt/mTOR signalling. in Bioscience reports 2014 (PubMed)
    Show all 4 references for 676403

  5. Human Polyclonal MTOR Primary Antibody for IF, IHC (p) - ABIN196962 : Holz, Blenis: Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase. in The Journal of biological chemistry 2005 (PubMed)
    Show all 4 references for 196962

  6. Human Polyclonal MTOR Primary Antibody for ELISA, WB - ABIN1532744 : Brown, Albers, Shin, Ichikawa, Keith, Lane, Schreiber: A mammalian protein targeted by G1-arresting rapamycin-receptor complex. in Nature 1994 (PubMed)
    Show all 3 references for 1532744

  7. Human Polyclonal MTOR Primary Antibody for ELISA, WB - ABIN1531715 : Onyango, Lubyova, Gardellin, Kurzbauer, Weith: Molecular cloning and expression analysis of five novel genes in chromosome 1p36. in Genomics 1998 (PubMed)
    Show all 3 references for 1531715

  8. Human Polyclonal MTOR Primary Antibody for IF (p), IHC (p) - ABIN747158 : Yang, Wang, Wang, Zhang, Zhang, Lu, Wang: mTOR is involved in 17?-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1, and CCNE1. in Molecular reproduction and development 2015 (PubMed)
    Show all 2 references for 747158

  9. Human Polyclonal MTOR Primary Antibody for IHC, ELISA - ABIN1531910 : Luo, Yoneda, Ohmori, Sasaki, Shimbo, Eto, Kato, Miyano, Kobayashi, Sasahira, Chihara, Kuniyasu: Cancer usurps skeletal muscle as an energy repository. in Cancer research 2014 (PubMed)

  10. Human Polyclonal MTOR Primary Antibody for IF, IHC (p) - ABIN390217 : Cao, Dong, Meng, Liu, Liao, Liu: MiR-511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3. in Tumour biology 2015 (PubMed)

More Antibodies against MTOR Interaction Partners

Horse (Equine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

Human Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. High mTOR expression is associated with melanoma.

  2. Studies indicate that understanding mTOR network circuitry will provide insight into its deregulation in diabetes, cancer, and cardiovascular disease, but modeling in silico to elucidate how insulin (show INS Antibodies) activates mTORC2 (show CRTC2 Antibodies) remains poorly defined.

  3. Mutated MTOR identified in central nervous system germ cell tumors upregulated phosphorylation of the AKT (show AKT1 Antibodies) pathway proteins

  4. Findings demonstrate that the Akt (show AKT1 Antibodies)/mTOR pathway is upregulated in verrucous carcinoma of the oral cavity , indicating a role for this pathway in the development and progression of this malignancy.

  5. IL-37 regulates autophagy in SMMC-7721 and Huh-7 cells via inhibition of the PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies)/mTOR signaling pathway.

  6. A nutrient-sensitive mTOR/ChREBP (show MLXIPL Antibodies) regulated transcriptional network could be a novel target to improve beta cell survival and glucose homeostasis in diabetes.

  7. Interleukin-37 induces apoptosis and autophagy of SMMC-7721 cells by inhibiting phosphorylation of mTOR.

  8. Abnormal mTOR activity may contribute to chemotherapy resistance, while it may also be effectively targeted via molecular means and/or development of specific pharmacological inhibitors.

  9. CXCR2 (show CXCR2 Antibodies) preferentially supports the maintenance of human pluripotent stem cell characteristics as well as facilitates ectodermal differentiation after the commitment to differentiation, and the mechanism might be associated with mTOR, beta-catenin (show CTNNB1 Antibodies), and hTERT activities.

  10. Data show that mTOR protein forms a complex with Raptor (show RPTOR Antibodies) and estrogen receptor-alpha (ERalpha (show ESR1 Antibodies)).

Mouse (Murine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. results establish a novel mechanism by which mTORC1 regulates Th1 differentiation, through control of T-bet phosphorylation

  2. Tsc2 (show TSC2 Antibodies)-mTOR signaling in mesenchyme is essential for the maintenance of renal structure and for lung alveolarization.

  3. This study suggests that mTOR activity in hepatocytes decreases hepatic vulnerability to injury through a mechanism dependent on NF-kappaB (show NFKB1 Antibodies) proinflammatory cytokine signaling pathway in both normal and steatotic liver.

  4. TSC1 (show TSC1 Antibodies)/TSC2 (show TSC2 Antibodies) complex upregulation of OPN (show SPP1 Antibodies) expression is mediated by transcription factor SOX9 (show SOX9 Antibodies) in an mTOR-independent manner. Moreover, ablation of OPN (show SPP1 Antibodies) by deficient TSC1 (show TSC1 Antibodies)/TSC2 (show TSC2 Antibodies) complex contributed to inactivation of AKT (show AKT1 Antibodies) in TSC (show SLC12A3 Antibodies) cells

  5. Suppressing mTOR signaling in in vitro-expanded Vgamma4 gammadelta T cells via the mechanistic inhibitor rapamycin enhanced their cytotoxicity against multiple tumor cell lines, and these cells performed better tumor-suppressing effects upon adoptive therapy. mTOR signaling plays an important role in the cytotoxic effector function of gammadelta T cells.

  6. A nutrient-sensitive mTOR/ChREBP (show MLXIPL Antibodies) regulated transcriptional network could be a novel target to improve beta cell survival and glucose homeostasis in diabetes.

  7. Mycobacterium ulcerans mycolactone acts as an inhibitor of the mechanistic Target of Rapamycin (mTOR) signaling pathway by interfering with the assembly of the two distinct mTOR protein complexes mTORC1 and mTORC2 (show CRTC2 Antibodies)

  8. High mTOR expression is associated with pituitary tumor development.

  9. mTOR protein signaling promotes stable epidermal adhesion in the skin and accelerates wound healing.

  10. mTOR-sensitive perturbation of smooth muscle cell mechanosensing contributes to elastin (show ELN Antibodies) aortopathy.

Zebrafish Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. This study reveals the dramatic rescue effects of L-leucine stimulation of mTORC1 in RBS (show ESCO2 Antibodies) cells and supports that normal gene expression and translation requires ESCO2 (show ESCO2 Antibodies) function.

  2. By inhibiting mTOR signaling via Fbxw7 (show FBXW7 Antibodies), the amount of myelination during development is reduced.

  3. Apc mutations activate mechanistic target of rapamycin complex 1 in mice and zebrafish

  4. In our zebrafish model, autophagy induction does not depend on inhibition of the Tor pathway or activation of Tp53 (show TP53 Antibodies).

  5. TOR signaling is a common pathological pathway that can be leveraged for therapeutic benefits in cardiomyopathies of different origins.

  6. in addition to regulating cell growth and proliferation, TOR signaling controls the developmental program guiding epithelial morphogenesis in the intestine

Pig (Porcine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. The immunoprecipitation results also showed that high AA concentrations significantly increased the interaction of mTOR and PPARg (show PPARG Antibodies). In summary, PPARg (show PPARG Antibodies) plays an important role in the regulation of IGF-1 (show IGF1 Antibodies) secretion and gene expression in response to dietary protein.

  2. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (show AKT1 Antibodies)-mTOR-FOXO1 (show FOXO1 Antibodies) signaling and suppressing the activation of TLR4 (show TLR4 Antibodies) and/or NOD2 (show NOD2 Antibodies) signaling pathways.

  3. Data show that the amount of proteins related to mechanistic target of rapamycin (mTOR) signaling pathways decreased along crypt-villus axis (CVA).

  4. AMPK (show PRKAA1 Antibodies)-mTOR-autophagy signaling is altered by intrauterine growth restriction in newborn piglets.

  5. Uroguanylin (show GUCA2B Antibodies) modulates (Na++K+)ATPase (show ATP1A1 Antibodies) in a proximal tubule cells via cGMP/protein kinase (show CDK7 Antibodies) G, cAMP/protein kinase A, and mTOR pathways.

  6. mTOR is involved in 17beta-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1 (show CCND1 Antibodies), and CCNE1 (show CCNE1 Antibodies).

  7. L-Glutamine (show GFPT2 Antibodies) enhances enterocyte growth via activation of the mTOR.

  8. Arg, Leu, and Gln act coordinately to stimulate proliferation of pTr (show PTCHD3 Antibodies) cells through activation of the MTOR-RPS6K-RPS6 (show RPS6 Antibodies)-EIF4EBP1 (show EIF4EBP1 Antibodies) signal transduction pathway.

  9. Data indicate that the expression of MAP1LC3A (show MAP1LC3A Antibodies), B and autophagy-associated genes (ATG5 (show ATG5 Antibodies), mTOR, Beclin-1 (show BECN1 Antibodies)) was increased in normal pigs, while decreased in miniature pigs.

  10. Biochemical, cellular, and molecular data suggest that L-arginine (show GATM Antibodies) stimulates mTOR biosynthesis, mTOR signaling, and overall protein biosynthesis/turnover in placental/trophoblast and blastocyst/ectoderm cells thereby enhancing cell proliferation.

Cow (Bovine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. These findings suggest that mTOR is involved in the control of the expression of multiple genes in cattle, which may be triggered by the luteinizing hormone surge.

  2. 14-3-3gamma (show YWHAG Antibodies) affects mTOR protein pathway and regulates lactogenesis in dairy cow mammary epithelial cells.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2 (show JAK2 Antibodies)-STAT5 (show STAT5A Antibodies) and mTOR signaling pathways.

  4. Insulin (show INS Antibodies)-induced activation of phosphoinositide 3-kinase~mTOR pathway up-regulates tau protein via acceleration of protein synthesis in adrenal chromaffin cells, promoting neurite-like process outgrowth.

  5. IGF-I (show IGF1 Antibodies) down-regulated functional IGF-I receptor (show IGF1R Antibodies) via GSK-3beta (show GSK3b Antibodies) inhibition and mTOR activation; constitutive activity of GSK-3beta (show GSK3b Antibodies) maintained IGF-I receptor (show IGF1R Antibodies) level in nonstimulated cells.

  6. stimulation of mammary protein synthesis by amino acids and its enhancement by a combination of the lactogenic hormones hydrocortisone, insulin (show INS Antibodies), and prolactin (show PRL Antibodies) were associated with increased phosphorylation of the mTOR substrates

  7. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (show AKT1 Antibodies), mTOR, p70S6K (show RPS6KB1 Antibodies), and ERK1/2 (show MAPK1/3 Antibodies).

  8. prostaglandin F2alpha phosphorylates TSC2 (show TSC2 Antibodies) and activates mTOR and ribosomal protein S6 (show RPS6 Antibodies) kinase (show RPS6KB1 Antibodies) signaling in an AKT (show AKT1 Antibodies)-independent manner

  9. mTOR links IGF-I (show IGF1 Antibodies) and EGF (show EGF Antibodies) signaling in inhibiting the autophagy pathways.

MTOR (FRAP1) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Alternative names and synonyms associated with MTOR (FRAP1)

  • mechanistic target of rapamycin (serine/threonine kinase) (MTOR) antibody
  • mechanistic target of rapamycin (serine/threonine kinase) (Mtor) antibody
  • mechanistic target of rapamycin (serine/threonine kinase) (mtor) antibody
  • 2610315D21Rik antibody
  • AI327068 antibody
  • flat antibody
  • FRAP antibody
  • frap1 antibody
  • FRAP2 antibody
  • RAFT1 antibody
  • RAPT1 antibody
  • tor antibody
  • wu:fc22h08 antibody

Protein level used designations for FRAP1

FK506 binding protein 12-rapamycin associated protein 1 , FK506 binding protein 12-rapamycin associated protein 2 , FK506-binding protein 12-rapamycin complex-associated protein 1 , FKBP-rapamycin associated protein , FKBP12-rapamycin complex-associated protein 1 , mammalian target of rapamycin , rapamycin and FKBP12 target 1 , rapamycin associated protein FRAP2 , rapamycin target protein 1 , serine/threonine-protein kinase mTOR , FKBP-rapamycin associated protein (FRAP) , FKBP-rapamycin-associated protein FRAP , FKBP12-rapamycin complex-associated protein , angiopoietin-like factor CDT6 , RAPT1 , rapamycin and FKBP12 target-1 protein , target of rapamycin

GENE ID SPECIES
100051341 Equus caballus
419455 Gallus gallus
2475 Homo sapiens
56717 Mus musculus
56718 Rattus norvegicus
324254 Danio rerio
478232 Canis lupus familiaris
100127359 Sus scrofa
100139219 Bos taurus
100860902 Capra hircus
100271659 Ovis aries
Selected quality suppliers for anti-MTOR (FRAP1) Antibodies
Did you look for something else?