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Browse our anti-MTOR (FRAP1) Antibodies

Full name:
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) Antibodies (FRAP1)
On are 344 Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antibodies from 34 different suppliers available. Additionally we are shipping MTOR Kits (39) and MTOR Proteins (3) and many more products for this protein. A total of 400 MTOR products are currently listed.
2610315D21Rik, AI327068, flat, FRAP, frap1, FRAP2, RAFT1, RAPT1, tor, wu:fc22h08
list all antibodies Gene Name GeneID UniProt
FRAP1 2475 P42345
FRAP1 56717 Q9JLN9
FRAP1 56718 P42346

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All available anti-MTOR Antibodies

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Top referenced anti-MTOR Antibodies

  1. Human Polyclonal MTOR Primary Antibody for EIA, IHC (p) - ABIN117909 : Chase, Rao, Hofmann, Chang-Hasnain: 1550 nm high contrast grating VCSEL. in Optics express 2010 (PubMed)
    Show all 9 references for ABIN117909

  2. Dog (Canine) Polyclonal MTOR Primary Antibody for EIA, WB - ABIN401320 : McMahon, Choi, Lin, Abraham, Lawrence: The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin. in Molecular and cellular biology 2002 (PubMed)
    Show all 6 references for ABIN401320

  3. Human Polyclonal MTOR Primary Antibody for EIA, IF - ABIN501014 : Shamji, Nghiem, Schreiber: Integration of growth factor and nutrient signaling: implications for cancer biology. in Molecular cell 2003 (PubMed)
    Show all 4 references for ABIN501014

  4. Human Polyclonal MTOR Primary Antibody for ELISA, WB - ABIN1531715 : Brown, Albers, Shin, Ichikawa, Keith, Lane, Schreiber: A mammalian protein targeted by G1-arresting rapamycin-receptor complex. in Nature 1994 (PubMed)
    Show all 3 references for ABIN1531715

  5. Human Polyclonal MTOR Primary Antibody for ELISA, WB - ABIN1532744 : Onyango, Lubyova, Gardellin, Kurzbauer, Weith: Molecular cloning and expression analysis of five novel genes in chromosome 1p36. in Genomics 1998 (PubMed)
    Show all 3 references for ABIN1532744

  6. Human Polyclonal MTOR Primary Antibody for EIA, IHC (p) - ABIN358774 : Dowling, Zakikhani, Fantus, Pollak, Sonenberg: Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells. in Cancer research 2007 (PubMed)
    Show all 2 references for ABIN358774

  7. Human Polyclonal MTOR Primary Antibody for IF (p), IHC (p) - ABIN676403 : Li, Liu, Wang, Sun, Ding, Sun, Han, Wang: Follistatin could promote the proliferation of duck primary myoblasts by activating PI3K/Akt/mTOR signalling. in Bioscience reports 2014 (PubMed)
    Show all 2 references for ABIN676403

  8. Human Polyclonal MTOR Primary Antibody for IF (p), IHC (p) - ABIN747158 : Yang, Wang, Wang, Zhang, Zhang, Lu, Wang: mTOR is involved in 17?-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1, and CCNE1. in Molecular reproduction and development 2015 (PubMed)
    Show all 2 references for ABIN747158

  9. Human Polyclonal MTOR Primary Antibody for IF, IHC (p) - ABIN390217 : Cao, Dong, Meng, Liu, Liao, Liu: MiR-511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3. in Tumour biology 2015 (PubMed)

  10. Human Polyclonal MTOR Primary Antibody for IHC, ELISA - ABIN1531910 : Luo, Yoneda, Ohmori, Sasaki, Shimbo, Eto, Kato, Miyano, Kobayashi, Sasahira, Chihara, Kuniyasu: Cancer usurps skeletal muscle as an energy repository. in Cancer research 2014 (PubMed)

More Antibodies against MTOR Interaction Partners

Horse (Equine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

Human Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. our findings provide for the first time that PF-04691502 inhibits the constitutively activated PI3K (show PIK3CA Antibodies)/mTOR pathway in aggressive B-cell NHL (show RTEL1 Antibodies) cell lines associated with inhibition of cell cycle progression, cell proliferation and promotion of apoptosis.

  2. Data suggest that combination of proto-oncogene (show RAB1A Antibodies) protein B (show LEPREL2 Antibodies)-raf (BRAF (show BRAF Antibodies)) and mTOR serine-threonine kinase (show TLK2 Antibodies) (mTOR) inhibition forms the basis of a treatment regimen of thyroid cancer.

  3. the combination of an mTOR inhibitor and an autophagy inhibitor may be effective in the treatment of osteosarcoma because it effectively induces the apoptotic pathway.

  4. Data suggest that nitroxoline induces anticancer activity through AMP (show APRT Antibodies)-activated kinase (AMPK (show PRKAA1 Antibodies))/mTOR serine-threonine kinase (show TLK2 Antibodies) (mTOR) signaling pathway via checkpoint kinase 2 (Chk2 (show CHEK2 Antibodies)) activation.

  5. Collybistin (show Arhgef9 Antibodies) forms a complex with mTOR and eIF3 (show EIF3A Antibodies) and by sequestering these proteins downregulates mTORC1 signaling and protein synthesis potentially contributing to intellectual disability and autism.

  6. Akt (show AKT1 Antibodies)/mTOR signaling was hyperactive in low miR (show MLXIP Antibodies)-149 expressing gliomas.

  7. 4E-BP1 (show EIF4EBP1 Antibodies) and p53 (show TP53 Antibodies) gene expressions were increased, but p-4E-BP1 (show EIF4EBP1 Antibodies) and p-mTOR protein expressions were decreased in nsclc.

  8. Study provides further evidence for the role of mTOR hyperactivation and reduced autophagy in the accumulation of protein oxidative damage during Down's Syndrome

  9. Data show that puquitinib mesylate (XC-302) induced autophagy in nasopharyngeal cancer cells CNE-2 by promoting cell autophagy and inhibits the phosphatidylinositol 3-Kinase (PI3K (show PIK3CA Antibodies))/AKT (show AKT1 Antibodies) protein/TOR (show RORC Antibodies) serine-threonine kinases (mTOR) signaling pathway.

  10. Data show that mTOR serine-threonine kinase (show TLK2 Antibodies) (mTOR) inhibitor AZD2014 has broad antiproliferative effects across multiple cell lines.

Mouse (Murine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. analysis of mTORC2 (show CRTC2 Antibodies) components mTOR, Rictor (show RICTOR Antibodies) and mSin1 reveals diurnal variation in mouse perivascular adipose tissue

  2. Study provides further evidence for the role of mTOR hyperactivation and reduced autophagy in the accumulation of protein oxidative damage during Down's Syndrome

  3. Chronic treatment with fluoxetine can induce synaptic protein expression by activating the mTOR signaling pathway.

  4. Hyperactive mTOR signaling combined with loss of p53 (show TP53 Antibodies) in mice induces tumors similar to human acinar cell carcinoma.

  5. miR (show MLXIP Antibodies)-3188 regulates nasopharyngeal carcinoma proliferation and chemosensitivity through a FOXO1 (show FOXO1 Antibodies)-modulated positive feedback loop with mTOR-p-PI3K/AKT (show AKT1 Antibodies)-c-JUN (show JUN Antibodies).

  6. sustained activation of mTORC1 signaling in skeletal muscle regulated whole-body metabolism through the induction of FGF21 (show FGF21 Antibodies), which, over the long term, caused severe lipodystrophy

  7. autophagy via the TSC2 (show TSC2 Antibodies)-mTORC1 signaling pathway plays an important role in maintenance of cardiac function and mitochondrial quantity and size in the heart.

  8. Our study suggests that Ab25-35 induces autophagy and the PI3K/AKT (show AKT1 Antibodies)/mTOR/p70S6K (show RPS6KB1 Antibodies) pathway is involved in the process, which improves our understanding of the pathogenesis of Alzheimer's disease and provides an additional model for AD research

  9. mTOR signaling pathway did not play a major role in lung injury and autophagy of lung tissue cells induced by lipopolysaccharide

  10. mTOR inhibitor, sirolimus, suppresses the tumor's growth, suggesting that mTOR inhibitors might be effective in control of FLCN (show FLCN Antibodies)-deficient RCC (show XRCC1 Antibodies).

Zebrafish Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. By inhibiting mTOR signaling via Fbxw7 (show FBXW7 Antibodies), the amount of myelination during development is reduced.

  2. Apc mutations activate mechanistic target of rapamycin complex 1 in mice and zebrafish

  3. In our zebrafish model, autophagy induction does not depend on inhibition of the Tor pathway or activation of Tp53 (show TP53 Antibodies).

  4. TOR signaling is a common pathological pathway that can be leveraged for therapeutic benefits in cardiomyopathies of different origins.

  5. in addition to regulating cell growth and proliferation, TOR signaling controls the developmental program guiding epithelial morphogenesis in the intestine

Pig (Porcine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. Uroguanylin (show GUCA2B Antibodies) modulates (Na++K+)ATPase (show ATP1A1 Antibodies) in a proximal tubule cells via cGMP/protein kinase (show CDK7 Antibodies) G, cAMP/protein kinase A, and mTOR pathways.

  2. mTOR is involved in 17beta-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1 (show CCND1 Antibodies), and CCNE1 (show CCNE1 Antibodies).

  3. L-Glutamine (show GFPT2 Antibodies) enhances enterocyte growth via activation of the mTOR.

  4. Arg, Leu, and Gln act coordinately to stimulate proliferation of pTr (show PTCHD3 Antibodies) cells through activation of the MTOR-RPS6K-RPS6 (show RPS6 Antibodies)-EIF4EBP1 (show EIF4EBP1 Antibodies) signal transduction pathway.

  5. Data indicate that the expression of MAP1LC3A (show MAP1LC3A Antibodies), B and autophagy-associated genes (ATG5 (show ATG5 Antibodies), mTOR, Beclin-1 (show BECN1 Antibodies)) was increased in normal pigs, while decreased in miniature pigs.

  6. Biochemical, cellular, and molecular data suggest that L-arginine (show GATM Antibodies) stimulates mTOR biosynthesis, mTOR signaling, and overall protein biosynthesis/turnover in placental/trophoblast and blastocyst/ectoderm cells thereby enhancing cell proliferation.

  7. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK (show PRKAA1 Antibodies)/ERK (show MAPK1 Antibodies)/TSC2 (show TSC2 Antibodies)/mTOR signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

  8. Findings illustrate a mechanism for the cardioprotective effects of lovastatin through inhibition of Rheb (show RHEB Antibodies) and mTORC1 and promotion of a differentiated vascular smooth muscle cell phenotype.

Cow (Bovine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. 14-3-3gamma (show YWHAG Antibodies) affects mTOR protein pathway and regulates lactogenesis in dairy cow mammary epithelial cells.

  2. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2 (show JAK2 Antibodies)-STAT5 (show STAT5A Antibodies) and mTOR signaling pathways.

  3. Insulin (show INS Antibodies)-induced activation of phosphoinositide 3-kinase~mTOR pathway up-regulates tau protein via acceleration of protein synthesis in adrenal chromaffin cells, promoting neurite-like process outgrowth.

  4. IGF-I (show IGF1 Antibodies) down-regulated functional IGF-I receptor (show IGF1R Antibodies) via GSK-3beta (show GSK3b Antibodies) inhibition and mTOR activation; constitutive activity of GSK-3beta (show GSK3b Antibodies) maintained IGF-I receptor (show IGF1R Antibodies) level in nonstimulated cells.

  5. stimulation of mammary protein synthesis by amino acids and its enhancement by a combination of the lactogenic hormones hydrocortisone, insulin (show INS Antibodies), and prolactin (show PRL Antibodies) were associated with increased phosphorylation of the mTOR substrates

  6. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (show AKT1 Antibodies), mTOR, p70S6K (show RPS6KB1 Antibodies), and ERK1/2 (show MAPK1/3 Antibodies).

  7. prostaglandin F2alpha phosphorylates TSC2 (show TSC2 Antibodies) and activates mTOR and ribosomal protein S6 (show RPS6 Antibodies) kinase (show RPS6KB1 Antibodies) signaling in an AKT (show AKT1 Antibodies)-independent manner

  8. mTOR links IGF-I (show IGF1 Antibodies) and EGF (show EGF Antibodies) signaling in inhibiting the autophagy pathways.

MTOR (FRAP1) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Alternative names and synonyms associated with MTOR (FRAP1)

  • mechanistic target of rapamycin (serine/threonine kinase) (MTOR) antibody
  • mechanistic target of rapamycin (serine/threonine kinase) (Mtor) antibody
  • mechanistic target of rapamycin (serine/threonine kinase) (mtor) antibody
  • 2610315D21Rik antibody
  • AI327068 antibody
  • flat antibody
  • FRAP antibody
  • frap1 antibody
  • FRAP2 antibody
  • RAFT1 antibody
  • RAPT1 antibody
  • tor antibody
  • wu:fc22h08 antibody

Protein level used designations for FRAP1

FK506 binding protein 12-rapamycin associated protein 1 , FK506 binding protein 12-rapamycin associated protein 2 , FK506-binding protein 12-rapamycin complex-associated protein 1 , FKBP-rapamycin associated protein , FKBP12-rapamycin complex-associated protein 1 , mammalian target of rapamycin , rapamycin and FKBP12 target 1 , rapamycin associated protein FRAP2 , rapamycin target protein 1 , serine/threonine-protein kinase mTOR , FKBP-rapamycin associated protein (FRAP) , FKBP-rapamycin-associated protein FRAP , FKBP12-rapamycin complex-associated protein , angiopoietin-like factor CDT6 , RAPT1 , rapamycin and FKBP12 target-1 protein , target of rapamycin

100051341 Equus caballus
419455 Gallus gallus
2475 Homo sapiens
56717 Mus musculus
56718 Rattus norvegicus
324254 Danio rerio
478232 Canis lupus familiaris
100127359 Sus scrofa
100139219 Bos taurus
100860902 Capra hircus
100271659 Ovis aries
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