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anti-Mouse (Murine) MTOR antibody for Flow Cytometry

Recommended MTOR Antibody (supplied by: Log in to see )

Antigen
Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antibodies
  • 2610315D21Rik
  • AI327068
  • flat
  • FRAP
  • frap1
  • Frap1
  • FRAP1
  • FRAP2
  • RAFT1
  • RAPT1
  • tor
  • wu:fc22h08
Epitope
pSer2448
65
24
24
23
22
21
14
13
13
10
7
6
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
340
164
151
8
2
2
2
1
1
Host
Mouse
293
46
2
Clonality
Monoclonal
Conjugate
This MTOR antibody is conjugated to PE
8
7
7
4
4
4
4
4
4
4
4
4
3
3
3
1
1
1
1
Application
Flow Cytometry (FACS), Intracellular Staining (ICS)
222
112
92
63
52
44
32
20
8
8
5
2
2
2
2
2
2
1
Supplier
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Available images

Catalog No. ABIN2680703
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.30391508 ABIN2680705 FACS ICS PerCP-eFluor® 710 Mouse IgG2a kappa pSer2448 Log in to see MRRBY
0.30391508 ABIN2680707 FACS ICS EFluor 660 Mouse IgG2a kappa pSer2448 Log in to see MRRBY

Similar anti-MTOR Antibodies

Application / Reactivity Mouse (Murine) Human
Chromatin Immunoprecipitation (ChIP) 1 Antibodies 1 Antibodies
ELISA 33 Antibodies 93 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies 8 Antibodies
Flow Cytometry (FACS) 3 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 8 Antibodies
Immunofluorescence (IF) 31 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 44 Antibodies
Immunohistochemistry (IHC) 49 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 31 Antibodies
Immunoprecipitation (IP) 9 Antibodies
Intracellular Staining (ICS) 3 Antibodies
Western Blotting (WB) 85 Antibodies
Dot Blot (DB) 2 Antibodies

General

Antigen Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antibodies
Epitope pSer2448
(65), (24), (24), (23), (22), (21), (14), (13), (13), (10), (7), (6), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(340), (164), (151), (8), (2), (2), (2), (1), (1)
Host Mouse
(293), (46), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MTOR antibody is conjugated to PE
(8), (7), (7), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Intracellular Staining (ICS)
(222), (112), (92), (63), (52), (44), (32), (20), (8), (8), (5), (2), (2), (2), (2), (2), (2), (1)
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Product Details anti-MTOR Antibody

Target Details MTOR Application Details Handling Images
Specificity This MRRBY monoclonal antibody recognizes human and mouse mammalian target of rapamycin (also known as mTOR, FRAP, RAFT) when phosphorylated on S2448. mTOR is a serine/threonine protein kinase that functions as an ATP and amino acid sensor as well as to balance nutrient availability with cell growth, proliferation, motility, survival, protein synthesis, and transcription. Activated mTOR increases production of enzymes necessary for glycolysis and controls the uptake of glucose and other nutrients. Increased glucose uptake and metabolism helps fulfill the energy needs for mTOR-driven cell growth and proliferation. When sufficient nutrients are available, mTOR transmits a positive signal to p70 S6 kinase and participates in the inactivation of the eIF4E inhibitor, 4E-BP1. mTOR is phosphorylated at S2448 via the PI3 kinase/Akt signaling pathway and is autophosphorylated at Ser2481. Due to its critical role in regulation of cell growth, survival, and metabolism, and because it is often abnormally regulated in tumors, mTOR is under investigation as a potential target for anti-cancer therapy.
Characteristics This MRRBY monoclonal antibody recognizes human and mouse mammalian target of rapamycin (also known as mTOR, FRAP, RAFT) when phosphorylated on S2448. mTOR is a serine/threonine protein kinase that functions as an ATP and amino acid sensor as well as to balance nutrient availability with cell growth, proliferation, motility, survival, protein synthesis, and transcription. Activated mTOR increases production of enzymes necessary for glycolysis and controls the uptake of glucose and other nutrients. Increased glucose uptake and metabolism helps fulfill the energy needs for mTOR-driven cell growth and proliferation. When sufficient nutrients are available, mTOR transmits a positive signal to p70 S6 kinase and participates in the inactivation of the eIF4E inhibitor, 4E-BP1. mTOR is phosphorylated at S2448 via the PI3 kinase/Akt signaling pathway and is autophosphorylated at Ser2481. Due to its critical role in regulation of cell growth, survival, and metabolism, and because it is often abnormally regulated in tumors, mTOR is under investigation as a potential target for anti-cancer therapy.
Synonyms: Synonyms: mammalian target of rapamycin, FRAP, RAFT
Clone MRRBY
Isotype IgG2a kappa

Target Details MTOR

Product Details anti-MTOR Antibody Application Details Handling Images back to top
Antigen
Alternative Name mTOR (FRAP1 Antibody Abstract)
Research Area Cardiovascular, Cardiogenesis, Cell Cycle, DNA/RNA
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-MTOR Antibody Target Details MTOR Handling Images back to top
Application Notes Applications reported: This MRRBY antibody has been reported for use in intracellular staining followed by flow cytometric analysis.

Applications tested: Page 2 of 2 Anti-Human/Mouse phospho-mTOR (S2448) PE
Restrictions For Research Use only

Handling

Product Details anti-MTOR Antibody Target Details MTOR Application Details Images back to top
Buffer aqueous buffer, 0.09 % sodium azide, may contain carrier protein/stabilizer
Handling Advice Do not freeze. Light-sensitive material.
Storage 4 °C
Storage Comment Store at 2-8°C.

Images

Product Details anti-MTOR Antibody Target Details MTOR Application Details Handling back to top
Supplier Images
Flow Cytometry (FACS) image for anti-MTOR antibody (Mechanistic Target of Rapamycin (serine/threonine Kinase)) (pSer2448) (PE) (ABIN2680703) anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) (pSer2448) antibody (PE)