You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our anti-PDK1 (PDK1) Antibodies

Full name:
anti-Pyruvate Dehydrogenase Kinase, Isozyme 1 Antibodies (PDK1)
On www.antibodies-online.com are 145 Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) Antibodies from 20 different suppliers available. Additionally we are shipping PDK1 Proteins (19) and PDK1 Kits (6) and many more products for this protein. A total of 179 PDK1 products are currently listed.
Synonyms:
B830012B01, D530020C15Rik, si:zfos-979f1.3
list all antibodies Gene Name GeneID UniProt
PDK1 228026 Q8BFP9
PDK1 5163 Q15118
PDK1 116551  

Show all species

Show all synonyms

Most Popular Reactivities for anti-PDK1 (PDK1) Antibodies

Select your species and application

anti-Mouse (Murine) PDK1 Antibodies:

anti-Human PDK1 Antibodies:

anti-Rat (Rattus) PDK1 Antibodies:

All available anti-PDK1 Antibodies

Go to our pre-filtered search.

Top referenced anti-PDK1 Antibodies

  1. Human Monoclonal PDK1 Primary Antibody for EIA, FACS - ABIN1108608 : Pinner, Sahai: PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE. in Nature cell biology 2008 (PubMed)
    Show all 3 references for ABIN1108608

  2. Human Monoclonal PDK1 Primary Antibody for ICC, FACS - ABIN969347 : Seong, Jung, Kim, Ha: 3-Phosphoinositide-dependent PDK1 negatively regulates transforming growth factor-beta-induced signaling in a kinase-dependent manner through physical interaction with Smad proteins. in The Journal of biological chemistry 2007 (PubMed)
    Show all 3 references for ABIN969347

  3. Human Polyclonal PDK1 Primary Antibody for EIA, WB - ABIN359095 : Frödin, Antal, Dümmler, Jensen, Deak, Gammeltoft, Biondi: A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation. in The EMBO journal 2002 (PubMed)
    Show all 3 references for ABIN359095

  4. Human Polyclonal PDK1 Primary Antibody for ELISA, WB - ABIN185505 : Sarbassov, Guertin, Ali, Sabatini: Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. in Science (New York, N.Y.) 2005 (PubMed)

  5. Cow (Bovine) Polyclonal PDK1 Primary Antibody for WB - ABIN2777432 : Ohba, Watanabe, Murakami, Radovanovic, Iino, Ishida, Tosa, Ono, Ito: Amlodipine inhibits cell proliferation via PKD1-related pathway. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against PDK1 Interaction Partners

Mouse (Murine) Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) interaction partners

  1. PDK1 (show PDPK1 Antibodies) plays a pivotal role in regulating cardiac function and tumor metastasis by interfering with microenvironment.

  2. Our data suggest that two arms of the glucose metabolism synergistically regulate the differential activation of macrophages. Our findings also highlight the central role of PDK1 (show PDPK1 Antibodies) in this event via controlling glycolysis and glucose oxidation.

  3. PDHK1 is expressed in Th17 cells, but not Th1 (show HAND1 Antibodies) cells, and at low levels in Tregs, and inhibition or knockdown of PDHK1 selectively suppressed Th17 cells and increased Tregs.

  4. The tyrosine phosphorylation enhances PDHK1 kinase activity by promoting ATP and PDC (show PDC Antibodies) binding.

  5. Pdk1 (show PDPK1 Antibodies) enzyme is critical in conserving mitochondrial function by diverting metabolic intermediates to glycolysis

Human Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) interaction partners

  1. PDK1 was specifically required for metabolic adaptation to nutrient limitation and hypoxia.

  2. High expression of PDK1 is associated with Colon Cancer.

  3. both PDK 1 and 2 isoforms are overexpressed in cutaneous melanoma compared to nevi, this expression being associated with the expression of the mTOR (show FRAP1 Antibodies) pathway effectors and independent of the BRAF (show BRAF Antibodies) mutational status

  4. Lin28A (show LIN28A Antibodies) and Lin28B (show LIN28B Antibodies) enhance, whereas let-7 suppresses, aerobic glycolysis via targeting pyruvate dehydrogenase kinase 1, or PDK1.

  5. Follow-up replication analyses in up to an additional 21,345 participants identified three new fasting plasma glucose loci reaching genome-wide significance in or near PDK1-RAPGEF4 (show RAPGEF4 Antibodies), KANK1 (show ANKRD15 Antibodies), and IGF1R (show IGF1R Antibodies).

  6. NOR1 (show NR4A3 Antibodies) expression causes apoptosis of tumor cells in hypoxia by altering the expression of PDK1 expression and mitochondrial Bax (show BAX Antibodies)-Bcl2 (show BCL2 Antibodies) balance thus suppress tumor cell adaptation to hypoxia

  7. Accordingly, elevated levels of PDK1, PDK3, and PKM2 and reduced PK activity could be observed in iPSCs and human embryonic stem cells in the undifferentiated state

  8. High expression of pyruvate dehydrogenase kinase-1 is associated with gastric cancer.

  9. post-mortem brain extracts from patients with Alzheimer disease exhibited a decrease in PDK1 expression compared with nondemented patients.

  10. Pyruvate dehydrogenase kinase 1 is an important regulator of pyruvate dehydrogenase (show PDP Antibodies) in clonal pancreatic beta-cells.

Pig (Porcine) Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) interaction partners

  1. Dephosphorylation of PDK1 may be a molecular switch for enhancement of protein tyrosine phosphorylation and flagellar hyperactivation in boar spermatozoa.

PDK1 Antigen Profile

Antigen Summary

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.

Alternative names and synonyms associated with PDK1

  • pyruvate dehydrogenase kinase, isozyme 1 (PDK1) antibody
  • pyruvate dehydrogenase kinase, isoenzyme 1 (Pdk1) antibody
  • pyruvate dehydrogenase kinase, isozyme 1 (Pdk1) antibody
  • pyruvate dehydrogenase kinase, isozyme 1 (pdk1) antibody
  • B830012B01 antibody
  • D530020C15Rik antibody
  • si:zfos-979f1.3 antibody

Protein level used designations for PDK1

pyruvate dehydrogenase kinase, isoenzyme 1 , pyruvate dehydrogenase kinase, isozyme 1 , pyruvate dehydrogenase [lipoamide] kinase isozyme 1, mitochondrial-like , PDH kinase 1 , [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial , mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1 , PDK p48 , pyruvate dehydrogenase kinase 1

GENE ID SPECIES
100218846 Taeniopygia guttata
100402844 Callithrix jacchus
100601990 Nomascus leucogenys
228026 Mus musculus
5163 Homo sapiens
116551 Rattus norvegicus
555840 Danio rerio
425972 Gallus gallus
100286871 Sus scrofa
528655 Bos taurus
476828 Canis lupus familiaris
432080 Xenopus laevis
100064091 Equus caballus
100351323 Oryctolagus cuniculus
Selected quality suppliers for anti-PDK1 (PDK1) Antibodies
Did you look for something else?