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|Antigen||Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This PDK2 antibody is conjugated to Alexa Fluor 555 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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Product Details anti-PDK2 AntibodyTarget Details PDK2 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human PDK2|
Target Details PDK2Product Details anti-PDK2 Antibody Application Details Handling Images back to top
|Alternative Name||Pdk2 (PDK2 Antibody Abstract)|
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].
Synonyms: PDHK2, Pyruvate dehydrogenase kinase isoform 2, pyruvate dehydrogenase kinase, isozyme 2, Pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial, PDK2_HUMAN.
|Research Area||Cancer, Metabolism|
|Pathways||PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process|
Application DetailsProduct Details anti-PDK2 Antibody Target Details PDK2 Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-PDK2 Antibody Target Details PDK2 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|