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anti-Rat (Rattus) PDPK1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended PDPK1 Antibody (supplied by: Log in to see )

Antigen
3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) Antibodies
  • 1210
  • BG02759
  • CD79B
  • CG1201
  • CG1210
  • Dmel\\CG1210
  • dPDK-1
  • dPDK1
  • Dstpk61
  • DSTPK61
  • dSTPK61
  • LOC100304995
  • MGC82080
  • PDK
  • PDK-1
  • PDK1
  • Pdk1
  • PDK1/Pk61C
  • pdpk1
  • PDPK2
  • Pk61C
  • pk61c
  • PK61C
  • Pk61C/PDK1
  • PRO0461
  • zgc:153787
Epitope
pSer241
48
20
19
13
13
13
13
11
8
7
6
6
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
260
149
147
7
6
4
4
2
1
1
1
1
1
Host
Rabbit
231
31
1
Clonality
Polyclonal
Conjugate
This PDPK1 antibody is un-conjugated
11
9
9
9
9
7
7
7
7
7
7
7
2
2
2
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
144
76
66
56
41
25
12
11
6
4
3
1
1
1
1
Supplier
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Catalog No. ABIN744668
$ 291.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00087819446 ABIN711116 IF (p) IHC (p) WB Rabbit IgG pTyr9 Log in to see Polyclonal
0.00087819446 ABIN682948 IF (p) IHC (p) WB Rabbit IgG pTyr373, pTyr376 Log in to see Polyclonal
0.00087819446 ABIN2814978 IF (p) Alexa Fluor 594 Rabbit IgG AA 220-260, pSer241 Log in to see Polyclonal
0.00087819446 ABIN875960 IF (p) Alexa Fluor 350 Rabbit IgG pSer393 Log in to see Polyclonal
0.00087819446 ABIN875961 IF (p) Alexa Fluor 488 Rabbit IgG pSer393 Log in to see Polyclonal
0.00087819446 ABIN875962 IF (p) Alexa Fluor 555 Rabbit IgG pSer393 Log in to see Polyclonal
0.00087819446 ABIN875963 IF (p) Alexa Fluor 647 Rabbit IgG pSer393 Log in to see Polyclonal
0.00087819446 ABIN875990 IF (p) Alexa Fluor 350 Rabbit IgG pSer396 Log in to see Polyclonal
0.00087819446 ABIN875989 IF (p) Alexa Fluor 488 Rabbit IgG pSer396 Log in to see Polyclonal
0.00087819446 ABIN875992 IF (p) Alexa Fluor 647 Rabbit IgG pSer396 Log in to see Polyclonal
0.00087819446 ABIN875991 IF (p) Alexa Fluor 555 Rabbit IgG pSer396 Log in to see Polyclonal
0.00087819446 ABIN876049 IF (p) Alexa Fluor 555 Rabbit IgG pSer410 Log in to see Polyclonal
0.00087819446 ABIN876050 IF (p) Alexa Fluor 350 Rabbit IgG pSer410 Log in to see Polyclonal
0.00087819446 ABIN876052 IF (p) Alexa Fluor 647 Rabbit IgG pSer410 Log in to see Polyclonal
0.00087819446 ABIN876051 IF (p) Alexa Fluor 488 Rabbit IgG pSer410 Log in to see Polyclonal
0.00087819446 ABIN880352 IF (p) Alexa Fluor 350 Rabbit IgG pTyr9 Log in to see Polyclonal
0.00087819446 ABIN880353 IF (p) Alexa Fluor 488 Rabbit IgG pTyr9 Log in to see Polyclonal
0.00087819446 ABIN880354 IF (p) Alexa Fluor 647 Rabbit IgG pTyr9 Log in to see Polyclonal
0.00087819446 ABIN880351 IF (p) Alexa Fluor 555 Rabbit IgG pTyr9 Log in to see Polyclonal
0.00087819446 ABIN879573 IF (p) Alexa Fluor 488 Rabbit IgG pTyr373, pTyr376 Log in to see Polyclonal

Top referenced anti-PDPK1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Similar anti-PDPK1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 17 Antibodies 16 Antibodies
Immunocytochemistry (ICC) 4 Antibodies 4 Antibodies
Immunofluorescence (IF) 14 Antibodies 15 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 77 Antibodies 77 Antibodies
Immunohistochemistry (IHC) 36 Antibodies 37 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 25 Antibodies 26 Antibodies
Immunoprecipitation (IP) 5 Antibodies 6 Antibodies
Intracellular Staining (ICS) 3 Antibodies 3 Antibodies
Western Blotting (WB) 67 Antibodies 68 Antibodies
Dot Blot (DB) 11 Antibodies

General

Antigen 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) Antibodies
Epitope pSer241
(48), (20), (19), (13), (13), (13), (13), (11), (8), (7), (6), (6), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(260), (149), (147), (7), (6), (4), (4), (2), (1), (1), (1), (1), (1)
Host Rabbit
(231), (31), (1)
Clonality
Polyclonal
Conjugate This PDPK1 antibody is un-conjugated
(11), (9), (9), (9), (9), (7), (7), (7), (7), (7), (7), (7), (2), (2), (2), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(144), (76), (66), (56), (41), (25), (12), (11), (6), (4), (3), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-PDPK1 Antibody

Target Details PDPK1 Application Details Handling References for anti-PDPK1 Antibody (ABIN744668) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human PDK1 around the phosphorylation site of Ser241
Isotype IgG

Target Details PDPK1

Product Details anti-PDPK1 Antibody Application Details Handling References for anti-PDPK1 Antibody (ABIN744668) Images back to top
Antigen
Alternative Name Pdk1 (PDPK1 Antibody Abstract)
Background

PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.


Synonyms: PDK1Ser241, PDPK1 phospho S241, PDPK1S241, 3 phosphoinositide dependent protein kinase 1, hPDK 1, hPDK1, MGC20087 MGC35290, PDK 1, PDPK 1, PDPK1, PkB kinase, PkB kinase like gene 1, PkB like 1, PkB like, PRO0461, PDPK1_HUMAN.
Gene ID 5170
Research Area Signaling, Cytoskeleton, Microfilaments, Kinases/Phosphatases
Pathways PI3K-Akt Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-PDPK1 Antibody Target Details PDPK1 Handling References for anti-PDPK1 Antibody (ABIN744668) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-PDPK1 Antibody Target Details PDPK1 Application Details References for anti-PDPK1 Antibody (ABIN744668) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-PDPK1 Antibody (ABIN744668)

Product Details anti-PDPK1 Antibody Target Details PDPK1 Application Details Handling Images back to top
Product cited in:

Lin, Lin, Kang, Liu, Wang, Zheng, Yu, Lin: "Similar PDK1-AKT-mTOR pathway activation in balloon cells and dysmorphic neurons of type II focal cortical dysplasia with refractory epilepsy." in: Epilepsy research, Vol. 112, pp. 137-49, 2015