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|Application / Reactivity||Human|
|Enzyme Immunoassay (EIA)||1 Antibodies|
|Immunochromatography (IC)||1 Antibodies|
|Immunocytochemistry (ICC)||2 Antibodies|
|Immunofluorescence (IF)||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Immunohistochemistry (IHC)||30 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||11 Antibodies|
|Immunoprecipitation (IP)||3 Antibodies|
|Western Blotting (WB)||60 Antibodies|
|Antigen||6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) Antibodies|
|Conjugate||This PFKFB2 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|2 references available|
|Supplier||Log in to see|
Product Details anti-PFKFB2 AntibodyTarget Details PFKFB2 Application Details Handling References for anti-PFKFB2 Antibody (ABIN360654) Images
|Specificity||This antibody reacts to PFKFB2.|
|Purification||Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PFKFB2.|
Target Details PFKFB2Product Details anti-PFKFB2 Antibody Application Details Handling References for anti-PFKFB2 Antibody (ABIN360654) Images back to top
|Alternative Name||PFKFB2 (PFKFB2 Antibody Abstract)|
|Background||Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).Synonyms: 6-biphosphatase 2, 6-phosphofructo-2-kinase/fructose-2, PFK-2/FBPase-2, PFK/FBPase 2, PFKFB cardiac|
|Gene ID||5208, 9606|
|Research Area||Cancer, Metabolism|
Application DetailsProduct Details anti-PFKFB2 Antibody Target Details PFKFB2 Handling References for anti-PFKFB2 Antibody (ABIN360654) Images back to top
ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-PFKFB2 Antibody Target Details PFKFB2 Application Details References for anti-PFKFB2 Antibody (ABIN360654) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-PFKFB2 Antibody (ABIN360654)Product Details anti-PFKFB2 Antibody Target Details PFKFB2 Application Details Handling Images back to top
Soejima, Kawamoto, Akai et al.: "Isolation of novel heart-specific genes using the BodyMap database." in: Genomics, Vol. 74, Issue 1, pp. 115-20, 2001 (PubMed).
Heine-Suñer, Díaz-Guillén, Lange et al.: "Sequence and structure of the human 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase heart isoform gene (PFKFB2)." in: European journal of biochemistry / FEBS, Vol. 254, Issue 1, pp. 103-10, 1998 (PubMed).
ImagesProduct Details anti-PFKFB2 Antibody Target Details PFKFB2 Application Details Handling References for anti-PFKFB2 Antibody (ABIN360654) back to top