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anti-Human PFKFB2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PFKFB2 Antibody (supplied by: Log in to see )

Antigen
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) Antibodies
  • 4930568D07Rik
  • PFK-2/FBPase-2
  • pfkfb2
  • RH2K
  • zgc:56282
Epitope
N-Term
31
11
8
5
3
1
1
1
1
1
1
1
Reactivity
Human
80
40
26
6
4
2
1
Host
Rabbit
76
7
3
Clonality
Polyclonal
Conjugate
This PFKFB2 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
64
39
29
11
9
3
2
2
1
Supplier
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Catalog No. ABIN360654
€ 371.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008913903 ABIN272060 IHC (p) WB Rabbit Log in to see Polyclonal
0.0008913903 ABIN392769 IHC (p) WB Rabbit Ig AA 1-30, N-Term Log in to see Polyclonal 3
0.0008913903 ABIN962679 IHC (p) ELISA Goat N-Term Log in to see Polyclonal
0.0008913903 ABIN1738023 IHC (p) ELISA Goat N-Term Log in to see Polyclonal
0.0008913903 ABIN708253 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.0008913903 ABIN708260 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.0008913903 ABIN1805382 IHC (p) WB Rabbit N-Term Log in to see Polyclonal
0.0008913903 ABIN708251 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008913903 ABIN408068 IHC (p) IHC WB Rabbit IgG Pro479 Log in to see Polyclonal
0.0008913903 ABIN2771571 IHC (p) IHC ELISA Goat N-Term Log in to see Polyclonal

Top referenced anti-PFKFB2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-PFKFB2 Antibodies

Application / Reactivity Human
ELISA 39 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 30 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Western Blotting (WB) 60 Antibodies

General

Antigen 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) Antibodies
Epitope N-Term
(31), (11), (8), (5), (3), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(80), (40), (26), (6), (4), (2), (1)
Host Rabbit
(76), (7), (3)
Clonality
Polyclonal
Conjugate This PFKFB2 antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(64), (39), (29), (11), (9), (3), (2), (2), (1)
Pubmed 2 references available
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Product Details anti-PFKFB2 Antibody

Target Details PFKFB2 Application Details Handling References for anti-PFKFB2 Antibody (ABIN360654) Images
Specificity This antibody reacts to PFKFB2.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PFKFB2.
Isotype Ig

Target Details PFKFB2

Product Details anti-PFKFB2 Antibody Application Details Handling References for anti-PFKFB2 Antibody (ABIN360654) Images back to top
Antigen
Alternative Name PFKFB2 (PFKFB2 Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).Synonyms: 6-biphosphatase 2, 6-phosphofructo-2-kinase/fructose-2, PFK-2/FBPase-2, PFK/FBPase 2, PFKFB cardiac
Gene ID 5208, 9606
UniProt O60825
Research Area Cancer, Metabolism
Pathways PI3K-Akt Signaling

Application Details

Product Details anti-PFKFB2 Antibody Target Details PFKFB2 Handling References for anti-PFKFB2 Antibody (ABIN360654) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PFKFB2 Antibody Target Details PFKFB2 Application Details References for anti-PFKFB2 Antibody (ABIN360654) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-PFKFB2 Antibody (ABIN360654)

Product Details anti-PFKFB2 Antibody Target Details PFKFB2 Application Details Handling Images back to top
Background publications

Soejima, Kawamoto, Akai, Miyoshi, Arai, Morohka, Matsuo, Niikawa, Kimura, Okubo, Mukai: "Isolation of novel heart-specific genes using the BodyMap database." in: Genomics, Vol. 74, Issue 1, pp. 115-20, 2001

Heine-Suñer, Díaz-Guillén, Lange, Rodríguez de Córdoba: "Sequence and structure of the human 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase heart isoform gene (PFKFB2)." in: European journal of biochemistry / FEBS, Vol. 254, Issue 1, pp. 103-10, 1998

Images

Product Details anti-PFKFB2 Antibody Target Details PFKFB2 Application Details Handling References for anti-PFKFB2 Antibody (ABIN360654) back to top
Supplier Images
 image for anti-PFKFB2 antibody (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2) (N-Term) (ABIN360654) anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (N-Term) antibody
 image for anti-PFKFB2 antibody (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2) (N-Term) (ABIN360654) anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (N-Term) antibody (Image 2)