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anti-Rat (Rattus) PIK3CA antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended PIK3CA Antibody (supplied by: Log in to see )

Antigen
Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) Antibodies
  • 6330412C24Rik
  • C-P3K
  • caPI3K
  • CLOVE
  • CWS5
  • MCAP
  • MCM
  • MCMTC
  • p110
  • p110-alpha
  • p110alpha
  • pi3-k
  • PI3-kinase
  • PI3K
  • pi3k
  • PI3K-alpha
Epitope
AA 1010-1050
34
16
14
13
13
9
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
141
47
41
7
4
2
1
1
1
Host
Rabbit
99
23
22
Clonality
Polyclonal
Conjugate
This PIK3CA antibody is un-conjugated
6
6
6
6
5
5
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
87
74
67
28
11
10
8
5
5
3
2
2
1
1
Supplier
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Catalog No. ABIN677198
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008812695 ABIN911090 IF (p) Alexa Fluor 350 Rabbit IgG AA 1010-1050 Log in to see Polyclonal
0.0008812695 ABIN911091 IF (p) Alexa Fluor 488 Rabbit IgG AA 1010-1050 Log in to see Polyclonal
0.0008812695 ABIN911093 IF (p) Alexa Fluor 647 Rabbit IgG AA 1010-1050 Log in to see Polyclonal
0.0008812695 ABIN911092 IF (p) Alexa Fluor 555 Rabbit IgG AA 1010-1050 Log in to see Polyclonal
0.0008812695 ABIN677202 IF (p) Cy5 Rabbit IgG AA 1010-1050 Log in to see Polyclonal
0.0008812695 ABIN677203 IF (p) Cy5.5 Rabbit IgG AA 1010-1050 Log in to see Polyclonal
0.0008812695 ABIN677204 IF (p) Cy7 Rabbit IgG AA 1010-1050 Log in to see Polyclonal
0.0008812695 ABIN677205 IF (p) FITC Rabbit IgG AA 1010-1050 Log in to see Polyclonal
0.0008812695 ABIN677201 IF (p) Cy3 Rabbit IgG AA 1010-1050 Log in to see Polyclonal
0.0008812695 ABIN2808910 IF (p) Alexa Fluor 594 Rabbit IgG AA 1010-1050 Log in to see Polyclonal

Top referenced anti-PIK3CA antibody for Immunofluorescence (Paraffin-embedded Sections)

Similar anti-PIK3CA Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
BioImaging (BI) 2 Antibodies 2 Antibodies 2 Antibodies
ELISA 6 Antibodies 8 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 2 Antibodies
Flow Cytometry (FACS) 2 Antibodies 2 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 14 Antibodies 17 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies 12 Antibodies
Immunoprecipitation (IP) 4 Antibodies 4 Antibodies
Western Blotting (WB) 24 Antibodies 30 Antibodies

General

Antigen Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) Antibodies
Epitope AA 1010-1050
(34), (16), (14), (13), (13), (9), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(141), (47), (41), (7), (4), (2), (1), (1), (1)
Host Rabbit
(99), (23), (22)
Clonality
Polyclonal
Conjugate This PIK3CA antibody is un-conjugated
(6), (6), (6), (6), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(87), (74), (67), (28), (11), (10), (8), (5), (5), (3), (2), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-PIK3CA Antibody

Target Details PIK3CA Application Details Handling References for anti-PIK3CA Antibody (ABIN677198) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human PI3KCA
Isotype IgG

Target Details PIK3CA

Product Details anti-PIK3CA Antibody Application Details Handling References for anti-PIK3CA Antibody (ABIN677198) Images back to top
Antigen
Alternative Name Pi3kca (PIK3CA Antibody Abstract)
Background

Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors. Involved in the activation of AKT1 upon stimulation by receptor tyrosine kinases ligands such as EGF, insulin, IGF1, VEGFA and PDGF. Involved in signaling via insulin-receptor substrate (IRS) proteins. Essential in endothelial cell migration during vascular development through VEGFA signaling, possibly by regulating RhoA activity. Required for lymphatic vasculature development, possibly by binding to RAS and by activation by EGF and FGF2, but not by PDGF. Regulates invadopodia formation in breast cancer cells through the PDPK1-AKT1 pathway. Participates in cardiomyogenesis in embryonic stem cells through a AKT1 pathway. Participates in vasculogenesis in embryonic stem cells through PDK1 and protein kinase C pathway. Has also serine-protein kinase activity: phosphorylates PIK3R1 (p85alpha regulatory subunit), EIF4EBP1 and HRAS.

Subcellular location: Cytoplasm, Membrane bound


Synonyms: MCM, CWS5, MCAP, PI3K, CLOVE, MCMTC, p11-alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, PI3-kinase subunit alpha, PI3K-alpha, PI3Kalpha, PtdIns-3-kinase subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase 11 kDa catalytic subunit alpha, PtdIns-3-kinase subunit p11-alpha, p11alpha, Phosphoinositide-3-kinase catalytic alpha polypeptide, Serine/threonine protein kinase PIK3CA, PIK3CA
Gene ID 5290
UniProt P42336
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-PIK3CA Antibody Target Details PIK3CA Handling References for anti-PIK3CA Antibody (ABIN677198) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-PIK3CA Antibody Target Details PIK3CA Application Details References for anti-PIK3CA Antibody (ABIN677198) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-PIK3CA Antibody (ABIN677198)

Product Details anti-PIK3CA Antibody Target Details PIK3CA Application Details Handling Images back to top
Product cited in:

Paul-Samojedny, Suchanek, Borkowska, Pude?ko, Owczarek, Kowalczyk, Machnik, Fila-Dani?ow, Kowalski: "Knockdown of AKT3 (PKB?) and PI3KCA suppresses cell viability and proliferation and induces the apoptosis of glioblastoma multiforme T98G cells." in: BioMed research international, Vol. 2014, pp. 768181, 2014