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Browse our PIK3CA (PIK3CA) ELISA Kits

Full name:
Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide ELISA Kits (PIK3CA)
On www.antibodies-online.com are 5 Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) ELISA Kits from 2 different suppliers available. Additionally we are shipping PIK3CA Antibodies (154) and PIK3CA Proteins (3) and many more products for this protein. A total of 170 PIK3CA products are currently listed.
Synonyms:
6330412C24Rik, C-P3K, caPI3K, CLOVE, CWS5, MCAP, MCM, MCMTC, p110, p110-alpha, p110alpha, pi3-k, PI3-kinase, PI3K, PI3K-alpha
list all ELISA KIts Gene Name GeneID UniProt
PIK3CA 18706 P42337
PIK3CA 5290 P42336
Rat PIK3CA PIK3CA 170911  

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PIK3CA (PIK3CA) ELISA Kits by Reactivity

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More ELISA Kits for PIK3CA Interaction Partners

Mouse (Murine) Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) interaction partners

  1. Results suggest a role of ST6GalNAc I (show ST6GALNAC1 ELISA Kits) in promoting the growth and invasion of hepatocarcinoma cells through regulating PI3K/AKT (show AKT1 ELISA Kits)/NF-kappa B (show NFKB1 ELISA Kits) signaling, and ST6GalNAc I (show ST6GALNAC1 ELISA Kits) might be a marker for the prognosis and therapy of hepatocarcinoma.

  2. PI3K signaling plays a modulatory role in the regulation of the transcriptional rhythm of the Dbp (show GC ELISA Kits) gene by targeting BMAL1 (show ARNTL ELISA Kits) and CLOCK.

  3. Analysis of 18 signalling signatures revealed that PI3K signalling is significantly induced whereas EGFR (show EGFR ELISA Kits) signalling is significantly reduced in Pten() versus PIK3CA(H1047R) tumors. Thus, Pten() and PIK3CA(H1047R) tumors exhibit discernable differences that may impact tumorigenesis and response to therapy.

  4. activating PIK3CA mutations gives rise to sporadic venous malformations in mice, which closely resemble the histology of the human disease.

  5. These data demonstrate a causal relationship between activating Pik3ca mutations and the genesis of vascular malformations.

  6. data demonstrate that the PI3K p110alpha-Akt (show AKT1 ELISA Kits)/Rac1 and NOX1 (show NOX1 ELISA Kits) signalling pathways play a pivotal role in VEGF (show VEGFA ELISA Kits)-induced vascular differentiation and cell migration.

  7. miR (show MLXIP ELISA Kits)-490-5p functions as a tumour suppressor in renal carcinoma (show TSC2 ELISA Kits) by targeting PIK3CA

  8. Thus, non-canonical phosphoinositide 3-kinase-antagonism by Itpkb (show ITPKB ELISA Kits) restricts pre-T cell receptor (show PTCRA ELISA Kits) induced metabolic activation to enforce coincidence-detection of pre-T cell receptor (show PTCRA ELISA Kits) expression and Notch (show NOTCH1 ELISA Kits)-engagement.

  9. Data show that RNA silencing of CCN family member 1 (show CYR61 ELISA Kits) protein (CCN1 (show CCNA2 ELISA Kits)) inhibits retinal neovascularization (RNV) by inhibiting phosphoinositide 3-kinase (PI3K)/AKT (show AKT1 ELISA Kits) protein signaling in mouse pup model of oxygen-induced retinopathy (OIR).

  10. Reelin (show RELN ELISA Kits) thus plays a role in restraining RAS and PI3-kinase promotion of cell motility and potentially tumour metastasis.

Human Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) interaction partners

  1. PTEN and PIK3CA were shown to be upregulated by 89 and 76% (western blot), respectively, in the pemetrexed-resistant cell line compared with control cells.

  2. High expression of PI3K is associated with glioma.

  3. PIK3CA mutations are associated with metastatic lung adenocarcinomas.

  4. Data show that zinc finger protein 143 (ZNF143 (show ZNF143 ELISA Kits)) promotes epithelial-mesenchymal transition (EMT (show ITK ELISA Kits)) through regulating PI3K/AKT (show AKT1 ELISA Kits) pathway in gastric cancer (GC) cells.

  5. Mutations in PIK3CA, AKT1 (show AKT1 ELISA Kits), and PTEN also were less frequently found in cancers with mutations in the DNA guardian, TP53 (show TP53 ELISA Kits). This observation might seem counterintuitive because increased genome instability might facilitate development and selection of advantageous mutations.

  6. PIK3CA, PTEN, and AKT1 mutations occurred more frequently in the presence of hormone receptor overexpression (androgen, progesterone, or estrogen receptor). PIK3CA mutations were also more common in the HER2-positive than in the HER2-negative group; the opposite pattern was seen for PTEN mutation or PTEN loss

  7. High PI3K expression is associated with prostate cancer.

  8. PIK3CA gene mutations are associated with breast cancer

  9. Study shows that PIK3CA mutation occurs approximately in 45% of breast cancer patients, and are frequent in exon 20 in comparison with exon 9 of the gene. Also, PIK3CA mutations were found significantly associated with low-grade tumors.

  10. Data show that microRNA miR (show MLXIP ELISA Kits)-221 targets PTEN protein, leading to activation of the PI3K/Akt (show AKT1 ELISA Kits) pathway.

Cow (Bovine) Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) interaction partners

  1. There are multiple conformations in equilibrium during the course of PI3K SH3 domain (show ITSN1 ELISA Kits) unfolding.

  2. PI3K has a role in activation of 5'-AMP (show TMPRSS5 ELISA Kits)-activated kinase during hypoxia-reoxygenation of bovine aortic endothelial cells

  3. Production of PtdIns3P by PI3K-C2alpha (show PIK3C2A ELISA Kits) is required for acquisition of fusion competence in neurosecretion.

  4. crystallographic and biochemical approaches used to gain insight into activating mutations in two noncatalytic p110alpha domains-the adaptor-binding and the helical domains

PIK3CA Antigen Profile

Antigen Summary

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.

Alternative names and synonyms associated with PIK3CA

  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (PIK3CA) Elisa Kit
  • Phosphoinositide-3-kinase, catalytic, alpha polypeptide (GL50803_14855) Elisa Kit
  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (pik3ca) Elisa Kit
  • phosphoinositide-3-kinase, catalytic, alpha polypeptide (LOC100337822) Elisa Kit
  • phosphatidylinositol 3-kinase, catalytic, alpha polypeptide (Pik3ca) Elisa Kit
  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (Pik3ca) Elisa Kit
  • phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA) Elisa Kit
  • 6330412C24Rik Elisa Kit
  • C-P3K Elisa Kit
  • caPI3K Elisa Kit
  • CLOVE Elisa Kit
  • CWS5 Elisa Kit
  • MCAP Elisa Kit
  • MCM Elisa Kit
  • MCMTC Elisa Kit
  • p110 Elisa Kit
  • p110-alpha Elisa Kit
  • p110alpha Elisa Kit
  • pi3-k Elisa Kit
  • PI3-kinase Elisa Kit
  • PI3K Elisa Kit
  • PI3K-alpha Elisa Kit

Protein level used designations for PIK3CA

phosphoinositide-3-kinase, catalytic, alpha polypeptide , Phosphoinositide-3-kinase, catalytic, alpha polypeptide , PI3-kinase subunit alpha , PI3K-alpha , PI3Kalpha , phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha , phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform , phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha , phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform , phosphoinositide-3-kinase catalytic alpha polypeptide , ptdIns-3-kinase subunit alpha , ptdIns-3-kinase subunit p110-alpha , serine/threonine protein kinase PIK3CA , PI3-kinase p110 subunit alpha , phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha , phosphatidylinositol 3-kinase, catalytic, alpha polypeptide , phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform , PI3K , p110alpha , ptdIns-3-kinase p110 , phosphoinositide 3-kinase catalytic subunit

GENE ID SPECIES
460858 Pan troglodytes
5702156 Giardia lamblia ATCC 50803
100144924 Xenopus (Silurana) tropicalis
100229768 Taeniopygia guttata
100337822 Oryctolagus cuniculus
18706 Mus musculus
5290 Homo sapiens
282306 Bos taurus
170911 Rattus norvegicus
488084 Canis lupus familiaris
424971 Gallus gallus
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