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Browse our PIK3CG Proteins (PIK3CG)

Full name:
Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Proteins (PIK3CG)
On www.antibodies-online.com are 3 Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) Proteins from 2 different suppliers available. Additionally we are shipping PIK3CG Antibodies (158) and many more products for this protein. A total of 169 PIK3CG products are currently listed.
Synonyms:
5830428L06Rik, p110gamma, p120-PI3K, PI3CG, Pi3k, PI3Kgamma, PIK3, wu:fb15d07, zgc:77033
list all proteins Gene Name GeneID UniProt
PIK3CG 5294 P48736
Rat PIK3CG PIK3CG 298947  
PIK3CG 30955 Q9JHG7

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PIK3CG Proteins (PIK3CG) by Origin

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More Proteins for PIK3CG Interaction Partners

Human Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) interaction partners

  1. Diminished expression of p110gamma in pulmonary vascular endothelial cells of patients with acute respiratory distress syndrome suggests that impaired p110gamma-FoxM1 vascular repair signaling is a critical factor in persistent leaky lung microvessels in ARDS.

  2. Findings suggest the pathophysiological role of phosphoinositide 3-kinase gamma (PI3Kgamma) in atherogenesis.

  3. Our findings suggest that p84 (show PPP1R12C Proteins) binding to p110gamma may represent a novel negative feedback signal that terminates PI3Kgamma activity.

  4. findings suggest that miR (show MLXIP Proteins)-502 functions as a tumor suppressor in HCC (show FAM126A Proteins) via inhibition of PI3KCG, supporting its utility as a promising therapeutic gene target for this tumor type

  5. PI3Kgamma plays an important role in the development of eosinophilic inflammation a

  6. PI3Kgamma-induced VEGF (show VEGFA Proteins) expression was reduced when the human tocopherol-associated protein (show SEC14L2 Proteins) 1 (hTAP1/SEC14L2 (show SEC14L2 Proteins)) was overexpressed suggesting formation of an inactive PI3Kgamma/hTAP1 heterodimer.

  7. data argue for differential regulatory functions of the non-catalytic subunits and a specific Gbetagamma-dependent regulation of p101 (show PIK3R5 Proteins) in PI3Kgamma activation.

  8. The interaction between PI3Kgamma and CNGA1 (show CNGA1 Proteins) does not appear to play a role in regulation of CNG (show CNGA1 Proteins) channel activity, but PI3Kgamma uses CNGA1 (show CNGA1 Proteins) as an anchoring module to achieve close proximity to its substrate to generate D3-phosphoinositides

  9. Mfng (show MFNG Proteins) is an oncogene (show RAB1A Proteins) acting through Notch (show NOTCH1 Proteins)-mediated induction of Pik3cg.

  10. increased susceptibility of individuals with COPD (show ARCN1 Proteins) to influenza likely results from impaired antiviral responses, which are mediated by increased PI3K-p110alpha (show PIK3CA Proteins) activity.

Pig (Porcine) Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) interaction partners

  1. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  2. CSF2 (show CSF2 Proteins) stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 MAPK (show MAPK1 Proteins)-dependent MTOR (show FRAP1 Proteins) signal transduction cascades.

  3. A linear relationship of EGF/EGFR (show EGFR Proteins), PI3-kinase (show PIK3CA Proteins), MAPK (show MAPK1 Proteins) and geminal vesicle breakdown, presents a relatively definitive mechanism of EGF (show EGF Proteins)-induced meiotic resumption of porcine oocyte.

Mouse (Murine) Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) interaction partners

  1. identify PI3Kgamma as a novel key host protective factor in influenza virus infection and shed light on an unappreciated layer of complexity concerning the role of PI3K signaling in this context

  2. Pik3cg(-/-) mice had persistent lung inflammation induced by sepsis and increased in vascular permeability. Restoration of p110gamma in pulmonary endothelial cellsrestored endothelial regeneration and normalized the defective vascular repair program.

  3. Results found that the absence of PI3Kgamma significantly delayed mortality and reduced clinical signs and histopathological brain changes associated with Plasmodium berghei infection.

  4. The authors demonstrate that the Attention Deficit Disorder with Hyperactivity phenotype depends on a dysregulation of CREB (show CREB1 Proteins) signaling exerted by a kinase-independent PI3Kgamma-PDE4D (show PDE4D Proteins) interaction in the noradrenergic neurons of the locus coeruleus.

  5. platelet PI3Kgamma contributes to platelet-mediated vascular inflammation and carotid intima-media thickening after flow severely reduced. Platelet PI3Kgamma may be a new target in the treatment of vascular diseases.

  6. The Ras-PI3Kgamma-Akt (show AKT1 Proteins)-mTOR (show FRAP1 Proteins) signaling axis acts downstream of FLT3L (show FLT3LG Proteins) signaling and is required for development of lung CD103 (show ITGAE Proteins)(+)and CD11b (show ITGAM Proteins)(+) dendritic cells. PI3Kgamma is an essential organ-specific regulator of lung dendritic cell development

  7. The regulatory subunits of PI3Kgamma control distinct neutrophil responses.

  8. p110 (show PIK3CA Proteins)[gamma] but not p110 (show PIK3CA Proteins)[delta]-specific inhibitor ameliorates renal ischemia-reperfusion injury by reducing necrosis and immune cell migration

  9. The interaction between PI3Kgamma and CNGA1 (show CNGA1 Proteins) does not appear to play a role in regulation of CNG (show CNGA1 Proteins) channel activity, but PI3Kgamma uses CNGA1 (show CNGA1 Proteins) as an anchoring module to achieve close proximity to its substrate to generate D3-phosphoinositides

  10. puerarin prevents Abeta (show APP Proteins)-induced microglial apoptosis via the activation of PI3K/Akt (show AKT1 Proteins) signaling pathway

PIK3CG Protein Profile

Protein Summary

This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.

Alternative names and synonyms associated with PIK3CG

  • phosphoinositide-3-kinase, catalytic, gamma polypeptide (pik3cg)
  • phosphoinositide-3-kinase, catalytic, gamma polypeptide (PIK3CG)
  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (PIK3CG)
  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (pik3cg)
  • phosphoinositide-3-kinase, catalytic, gamma polypeptide (LOC100344144)
  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (Pik3cg)
  • phosphoinositide-3-kinase, catalytic, gamma polypeptide (Pik3cg)
  • 5830428L06Rik protein
  • p110gamma protein
  • p120-PI3K protein
  • PI3CG protein
  • Pi3k protein
  • PI3Kgamma protein
  • PIK3 protein
  • wu:fb15d07 protein
  • zgc:77033 protein

Protein level used designations for PIK3CG

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform , phosphoinositide-3-kinase, catalytic, gamma polypeptide , phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform-like , 1-phosphatidylinositol 3-kinase , PI3-kinase subunit gamma , PI3K-gamma , p110-gamma , p110gamma , p120-PI3K , phosphatidylinositol 3 kinase gamma, p110 gamma , phosphatidylinositol 3-kinase catalytic 110-kD gamma , phosphatidylinositol 3-kinase, catalytic, gamma polypeptide , phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma , phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform , phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma , phosphoinositide-3-kinase gamma catalytic subunit , ptdIns-3-kinase subunit gamma , ptdIns-3-kinase subunit p110-gamma , serine/threonine protein kinase PIK3CG , PI3Kgamma , catalytic subunit of G-beta-gamma-activated , phosphoinositide-3-kinase catalytic gamma polypeptide

GENE ID SPECIES
406598 Danio rerio
417706 Gallus gallus
463649 Pan troglodytes
698857 Macaca mulatta
100158519 Xenopus (Silurana) tropicalis
100344144 Oryctolagus cuniculus
100394268 Callithrix jacchus
100453085 Pongo abelii
100586512 Nomascus leucogenys
5294 Homo sapiens
483266 Canis lupus familiaris
298947 Rattus norvegicus
396979 Sus scrofa
530001 Bos taurus
30955 Mus musculus
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