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Browse our Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme Proteins (PPP2CA)

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Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme Proteins (PPP2CA)
On www.antibodies-online.com are 10 Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) Proteins from 5 different suppliers available. Additionally we are shipping Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme Antibodies (134) and Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme Kits (5) and many more products for this protein. A total of 156 Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme products are currently listed.
Synonyms:
PP2A, Pp2a1, PP2Ac, PP2CA, PP2Calpha, PPP2CA, R75353, RP-C, zgc:110641
list all proteins Gene Name GeneID UniProt
PPP2CA 19052 P63330
PPP2CA 5515 P67775
PPP2CA 24672 P63331

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Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme Proteins (PPP2CA) by Origin

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More Proteins for Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme Interaction Partners

Mouse (Murine) Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) interaction partners

  1. PP2A (show PPP2R2B Proteins) activation both limited and prevented inflammation and tissue injury in two direct injury models of Acute respiratory distress syndrome.

  2. PP2A (show PPP2R2B Proteins) regulates kinetochore-microtubule attachment during meiosis I in oocyte.

  3. these results suggest that inhibiting PP2Ac nitration using a mimic peptide is a potential preventive strategy for Endothelial-to-mesenchymal transition in renal fibrosis

  4. Data suggest a critical role for the I2PP2A protein (SET)-protein phosphatase-2A (PP2A) signaling axis in Pten phosphohydrolase

  5. that loss of glucocerebrosidase function may contribute to SNCA accumulation through inhibition of autophagy via PPP2A inactivation

  6. Data indicate that protein phosphatase PP2A is required for the function of T(reg (show KCNH2 Proteins)) cells and the prevention of autoimmunity.

  7. data identify a molecular mechanism linking PP2A (show PPP2R2B Proteins) to the development of AD-related cognitive impairments that might be therapeutically exploited to target selectively the pathological effects caused by elevated Abeta (show APP Proteins) levels in AD patients

  8. PP2A (show PPP2R2B Proteins) has a role in mediating oxidative stress induced (show SQSTM1 Proteins) apoptosis in osteoblasts

  9. Our results show that D2R (show DRD2 Proteins) controls renal inflammation, at least in part, by modulation of the Akt (show AKT1 Proteins) pathway through effects on PP2A (show PPP2R2B Proteins) activity/expression.

  10. Concurrent mTORC1 inactivation and PP2A (show PPP2R2B Proteins)-B55alpha (show PPP2R2A Proteins) stimulation fuel ULK1 (show ULK1 Proteins)-dependent autophagy.

Human Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) interaction partners

  1. Binding of PP2A (show PPP2R4 Proteins) and Akt (show AKT1 Proteins) increased in response to cAMP or phosphatidic acid (PA), suggesting that their binding is directly responsible for the inactivation of Akt (show AKT1 Proteins) during decidualization.

  2. Knockdown of Alpha4 preferentially impacts the expression of PP4c (show PPP4C Proteins) and PP6c (show PPP6C Proteins) compared to expression levels of PP2Ac.

  3. these data support a role for the novel PP2Ac-CIN85 (show SH3KBP1 Proteins) complex in supporting integrin-dependent platelet function by dampening the phosphatase activity.

  4. PP2Ac upregulation has a poor prognostic impact on the overall survival of hepatocellular carcinoma (HCC (show FAM126A Proteins)) patients and contributes to the aggressiveness of HCC (show FAM126A Proteins). PP2Ac may represent a potential therapeutic target for HCC (show FAM126A Proteins).

  5. Data show that downregulating proto-oncogene (show RAB1A Proteins) protein Akt (p-Akt (show AKT1 Proteins)) by inhibiting PP2A (show PPP2R4 Proteins) inhibitor SET-mediated protein phosphatase 2A (PP2A (show PPP2R4 Proteins)) inactivation determined the pro-apoptotic effects of EMQA and paclitaxel combination treatment.

  6. Data suggest a critical role for the I2PP2A protein (SET)-protein phosphatase-2A (PP2A) signaling axis in Pten protein (Pten) deficient castration resistant prostate cancer (CRPC) progression.

  7. that loss of glucocerebrosidase function may contribute to SNCA accumulation through inhibition of autophagy via PPP2A inactivation

  8. Both PP-1 (show PPA1 Proteins) and PP-2A are directly involved in regulating eye development, and are aberrantly expressed in cataract and glaucoma patients. (Review)

  9. Data suggest that activation of TAZ (tafazzin (show TAZ Proteins)) inhibits adipogenesis in mesenchymal stem cells; interaction of TAZ (show TAZ Proteins) and protein phosphatases (PP1A (show PPP1CA Proteins), PP2A (show PPP2R4 Proteins)) up-regulates dephosphorylation and transport of TAZ (show TAZ Proteins) to cell nucleus.

  10. Data show that loss of epithelial membrane protein 2 (EMP2) is involved in sphingosylphosphorylcholine (SPC (show UCN3 Proteins))-induced phosphorylation of keratin 8 (show KRT8 Proteins) (K8) via ubiquitination of protein phosphatase 2 (PP2A (show PPP2R4 Proteins)) through alpha4 phosphoprotein (show IGBP1 Proteins) by caveolin-1 (cav-1 (show CAV1 Proteins)).

Cow (Bovine) Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) interaction partners

  1. changes in PP2A (show PPP2R2B Proteins) activity due to methylation and tyrosine phosphorylation occur in sperm; these changes may play an important role in the regulation of sperm function

  2. The findings demonstrate an endothelial VEGF (show VEGFA Proteins) resistance mechanism conferred by palmitic acid, which comprises ceramide-induced, PP2A (show PPP2R2B Proteins)-mediated dephosphorylation of critical activation sites on enzymes central to vascular homeostasis and angiogenesis.

Pig (Porcine) Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) interaction partners

  1. PP2A (show PPP2R2B Proteins) and AIP1 (show PDCD6IP Proteins) cooperatively induce activation of ASK1 (show MAP3K5 Proteins)-JNK (show MAPK8 Proteins) signaling and vascular endothelial cell apoptosis.

  2. Hsp27 (show HSPB1 Proteins) is dephosphorylated by PP2A (show PPP2R2B Proteins) in dorsal ruffles, in non-caveolar lipid raft microdomains.

Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) Protein Profile

Protein Summary

This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.

Alternative names and synonyms associated with Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA)

  • protein phosphatase 2, catalytic subunit, alpha isozyme (ppp2ca)
  • zgc:56064 (zgc:56064)
  • protein phosphatase 2, catalytic subunit, beta isozyme (ppp2cb)
  • protein phosphatase 2, catalytic subunit, alpha isozyme (PPP2CA)
  • protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform (ppp2ca)
  • protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform (Ppp2ca)
  • protein phosphatase 2, catalytic subunit, alpha isozyme (Ppp2ca)
  • protein phosphatase 2, catalytic subunit, beta isozyme (PPP2CB)
  • PP2A protein
  • Pp2a1 protein
  • PP2Ac protein
  • PP2CA protein
  • PP2Calpha protein
  • PPP2CA protein
  • R75353 protein
  • RP-C protein
  • zgc:110641 protein

Protein level used designations for PPP2CA

protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform , serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform , protein phosphatase 2a, catalytic subunit, alpha , protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform , protein phosphatase 2, catalytic subunit, beta isoform , protein phosphatase 2, catalytic subunit, alpha isozyme , serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform-like , PP2A-alpha , protein phosphatase 2a, catalytic subunit, alpha isoform , protein phosphatase 2A catalytic subunit, alpha isoform , replication protein C , serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform , protein phosphatase 2, catalytic subunit, alpha isoform , protein phosphatase-2A-alpha , type 2A protein phosphatase catalytic subunit , protein phosphatase 2A alpha subunit , phosphatase 2A catalytic subunit

GENE ID SPECIES
380045 Xenopus laevis
393885 Danio rerio
448031 Xenopus (Silurana) tropicalis
471633 Pan troglodytes
550585 Danio rerio
100461606 Pongo abelii
100596525 Nomascus leucogenys
19052 Mus musculus
5515 Homo sapiens
24672 Rattus norvegicus
282320 Bos taurus
416318 Gallus gallus
403608 Canis lupus familiaris
100009252 Oryctolagus cuniculus
397656 Sus scrofa
396021 Gallus gallus
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