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Browse our PPP2R1A Proteins (PPP2R1A)

Full name:
Protein Phosphatase 2, Regulatory Subunit A, alpha Proteins (PPP2R1A)
On www.antibodies-online.com are 4 Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A) Proteins from 3 different suppliers available. Additionally we are shipping PPP2R1A Antibodies (87) and many more products for this protein. A total of 97 PPP2R1A products are currently listed.
Synonyms:
6330556D22Rik, c-sis, pdgf2, PP2A, PP2A-Aalpha, PP2AAALPHA, ppp2r1a, PR65, PR65A, sis, ssv, wu:fa02h04, zgc:56296
list all proteins Gene Name GeneID UniProt
PPP2R1A 51792 Q76MZ3
PPP2R1A 5518 P30153
Rat PPP2R1A PPP2R1A 117281  

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PPP2R1A Proteins (PPP2R1A) by Origin

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Top referenced PPP2R1A Proteins

  1. Human PPP2R1A Protein expressed in Wheat germ - ABIN1316014 : Lao, Yusoff, Chandramouli, Philp, Fong, Jackson, Saw, Yu, Guy: Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation. in The Journal of biological chemistry 2007 (PubMed)

More Proteins for PPP2R1A Interaction Partners

Mouse (Murine) Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A) interaction partners

  1. oocyte-specific deletion of Ppp2r1a led to severe female subfertility without affecting follicle survival, growth, and ovulation.

  2. A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.

  3. PP2A (show PPP2R2B Proteins) (Protein Phosphatase 2A(Twins)) counteracts Plk4 (show PLK4 Proteins) autophosphorylation, thus stabilizing Plk4 (show PLK4 Proteins) and promoting centriole duplication

  4. PP2A (show PPP2R2B Proteins)-A alpha transcriptional regulation is mediated by multiple factors including AP-2alpha (show TFAP2A Proteins), CREB (show CREB1 Proteins), ETS-1 (show ETS1 Proteins), and SP-1 (show SP1 Proteins)

  5. Data show that DSB promote PP2A to associate with Ku 70 and Ku 86.

  6. protein phosphatase 2A overexpression in NIH 3T3 cells

  7. T-cell receptor (TCR)-dependent tyrosine phosphorylation may be the mechanism by which the regulatory subunit of PP2A (show PPP2R2B Proteins) prevents the inhibitory function of CTLA-4 (show CTLA4 Proteins), before TCR-CTLA-4 (show CTLA4 Proteins) coligation.

  8. PP-2A regulation of paxillin (show PXN Proteins) phosphorylation may have a role in controlling tumor cell adherence and motility.

  9. PP2A (show PPP2R2B Proteins) may contribute to melanoma cell radioresistance: the truncated isoform of the PP2A (show PPP2R2B Proteins) B56gamma regulatory subunit reduces irradiation-induced Mdm2 (show MDM2 Proteins) phosphorylation

  10. PP2A (show PPP2R2B Proteins) has a fundamental role in cardiac function

Human Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A) interaction partners

  1. PR65A phosphorylation regulates PP2A (show PPP2R4 Proteins) complex signaling.

  2. Our results suggest that IH-induced ROS generation increases PP2A activation and subsequently downregulates ERK1/2 activation, which results in inhibition of PC12 cell proliferation through G0/G1 phase arrest and NGF-induced neuronal differentiation.

  3. The two functional variants in PPP2R1A and PPP2R5E (show PPP2R5E Proteins) and their combinations are associated with lung cancer risk in the Chinese.

  4. Partial unfolding of PR65/A impacts catalysis by altering the proximity of bound catalytic subunit and substrate.

  5. For PPP2R1A, a heterozygous, somatic mutation (c.771G>T, p.W257C) was identified in 1 out of 37 patients (2.7%) with primary ovarian endometrioid carcinoma.

  6. gene transcription of PPP2R1A regulated by the polymorphism and methylation in the promoter region

  7. This study indicates that the PPP2R1A mutation occurs at a lower frequency compared to other gynecological malignancies, irrespective of the histological subtype

  8. the frequent mutation of PPP2R1A in the serous type of uterine cancer, a low frequency of mutation in endometrioid endometrial cancer and absence of mutation in uterine carcinosarcoma.

  9. Our findings suggest that functional genetic variants in the proximal promoter of the PP2A-Aalpha gene and their haplotypes are critical in the regulation of transcriptional activation.

  10. PPP2R1A somatic mutations occur in certain types of uterine and ovarian neoplastic lesions, especially uterine serous carcinomas

PPP2R1A Protein Profile

Protein Summary

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with PPP2R1A

  • protein phosphatase 2, regulatory subunit A, alpha (ppp2r1a)
  • platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) (pdgfb)
  • protein phosphatase 2, regulatory subunit A, alpha (PPP2R1A)
  • protein phosphatase 2, regulatory subunit A, alpha isoform (Ppp2r1a)
  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (Ppp2r1a)
  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (ppp2r1a)
  • protein phosphatase 2, regulatory subunit A, alpha (Ppp2r1a)
  • protein phosphatase 2, regulatory subunit A, alpha (ppp2r1a-a)
  • 6330556D22Rik protein
  • c-sis protein
  • pdgf2 protein
  • PP2A protein
  • PP2A-Aalpha protein
  • PP2AAALPHA protein
  • ppp2r1a protein
  • PR65 protein
  • PR65A protein
  • sis protein
  • ssv protein
  • wu:fa02h04 protein
  • zgc:56296 protein

Protein level used designations for PPP2R1A

protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform , platelet-derived growth factor subunit B , protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform , alpha isoform of regulatory subunit A, protein phosphatase 2 , protein phosphatase 2 (formerly 2A), regulatory subunit A , alpha isoform , protein phosphatase 2, regulatory subunit A, alpha , GLEAN_12508 , serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform , serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like , PP2A subunit A isoform PR65-alpha , PP2A subunit A isoform R1-alpha , protein phosphatase PP2A , serine/threonine protein phosphatase A subunit type 2A , protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform , medium tumor antigen-associated 61 KDA protein , serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform , medium tumor antigen-associated 61 kDa protein , protein phosphatase 2A 65 kDa regulatory subunit, alpha isoform

GENE ID SPECIES
395042 Xenopus (Silurana) tropicalis
448463 Xenopus (Silurana) tropicalis
468983 Pan troglodytes
583227 Strongylocentrotus purpuratus
641602 Tribolium castaneum
100173260 Pongo abelii
100369726 Saccoglossus kowalevskii
100413664 Callithrix jacchus
100598916 Nomascus leucogenys
51792 Mus musculus
406685 Danio rerio
5518 Homo sapiens
117281 Rattus norvegicus
535321 Bos taurus
484335 Canis lupus familiaris
397088 Sus scrofa
379827 Xenopus laevis
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