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Browse our PPP2R2B Proteins (PPP2R2B)

Full name:
Protein Phosphatase 2, Regulatory Subunit B, beta Proteins (PPP2R2B)
On www.antibodies-online.com are 14 Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B) Proteins from 3 different suppliers available. Additionally we are shipping PPP2R2B Antibodies (47) and many more products for this protein. A total of 66 PPP2R2B products are currently listed.
Synonyms:
2900026H06Rik, 6330404L05Rik, B55BETA, E130009M08Rik, PP2A, PP2A-PR55B, PP2AB55BETA, PP2ABBETA, PP2APR55B, PP2APR55BETA, PPP2R2B, ppp2r2b-a, ppp2r2c, Pppr2b2, PR2AB55BETA, PR2ABBETA, PR2APR55BETA, PR52B, PR55-BETA, PR55BETA, SCA12, zgc:101861
list all proteins Gene Name GeneID UniProt
PPP2R2B 72930 Q6ZWR4
PPP2R2B 5521 Q00005
PPP2R2B 60660 P36877

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PPP2R2B Proteins (PPP2R2B) by Origin

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More Proteins for PPP2R2B Interaction Partners

Mouse (Murine) Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B) interaction partners

  1. PP-2A is less abundant than PP-1 (show PPP1CC Proteins) in the mouse eye and appear to be highly regulated by various regulatory subunits; the genes encoding PP-1alpha/beta, PP-2Aalpha/beta, PP-2A-Aalpha/beta, and PP-2A-B alpha/beta/gamma are all differentially expressed.

Human Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B) interaction partners

  1. Thus, Fcp1 (show CTDP1 Proteins) coordinates Cdk1 (show CDK1 Proteins) and Gwl (show MASTL Proteins) inactivation to derepress PP2A (show PPP2R4 Proteins)-B55 (show MINK1 Proteins), generating a dephosphorylation switch that drives mitosis progression.

  2. investigated CAG copies within PPP2R2B in 29 patients with spinocerebellar ataxia (show USP14 Proteins) who are excluded from the most common subtypes; 3 patients carried 53, 46 and 54 CAG repeats respectively, while the other 26 cases harbored CAG repeats less than 30

  3. IER5 (show IER5 Proteins) functions as a positive feedback regulator of HSF1 (show HSF1 Proteins) and that this process involves PP2A (show PPP2R4 Proteins)/B55 (show MINK1 Proteins) and HSF1 (show HSF1 Proteins) dephosphorylation.

  4. Bcl-2 (show BCL2 Proteins) phosphorylation at Ser70 by selective tyrosine nitration of PP2A (show PPP2R4 Proteins)-B56delta stabilizes its antiapoptotic activity

  5. Inactivation of protein-phosphatase 2A causing hyperphosphorylation of paraprotein targets in monoclonal gammopathy of undetermined significance, multiple myeloma and Waldenstrom's macroglobulinemia is due to an exchange of its regulatory subunits

  6. Identification of the adenovirus E4orf4 protein binding site on the B55alpha (show PPP2R2A Proteins) and Cdc55 regulatory subunits of PP2A (show PPP2R4 Proteins): Implications for PP2A (show PPP2R4 Proteins)

  7. We demonstrate that PP2A/B55 is required for Gwl dephosphorylation at the essential Cdk site Thr194. Ensa/ARPP19 dephosphorylation is mediated by the RNA

  8. PP2A (show PPP2R4 Proteins)-B55beta promotes cyclin E1 (show CCNE1 Proteins) overexpression by antagonizing its degradation and its inhibition could represent a therapeutic mechanism for abrogating cyclin E1 (show CCNE1 Proteins) function in cancers

  9. Bod1 regulates protein phosphatase 2A at mitotic kinetochores.

  10. Differential autophagic neuronal cell death under stress is determined by the cytoplasmic and mitochondrial-specific PPP2R2B isoforms.

Cow (Bovine) Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B) interaction partners

  1. TRPV1 (show TRPV1 Proteins) activation in endothelial cells may elicit a Ca(2 (show CA2 Proteins)+) -dependent effect on PP2B-PKC signalling, which leads to dephosphorylation of eNOS (show NOS3 Proteins)

  2. The protein phosphatase PP2A/Balpha binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn (show FYN Proteins).

Xenopus laevis Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B) interaction partners

  1. equilibrium between CDK1 (show CDK1 Proteins) and PP2A specifies the timing of M-phase entry and exit and regulates the dynamics of cyclin B degradation upon M-phase exit in Xenopus laevis first embryonic mitosis.

  2. inhibition of PP2A-B55delta results from Ensa (show ENSA Proteins), that is phosphorylated in mitosis by the protein kinase (show CSNK1D Proteins) Greatwall (show MASTL Proteins); this converts Ensa (show ENSA Proteins) into specific inhibitor of PP2A-B55delta; this pathway represents a previously unknown element in mitosis control

  3. study describes how Gwl (show MASTL Proteins) activation results in PP2A inhibition; identified Arpp19 (show ARPP19 Proteins) and alpha-Endosulfine (show ENSA Proteins) that, when phosphorylated by Gwl (show MASTL Proteins), associate with and inhibit PP2A promoting mitotic entry

PPP2R2B Protein Profile

Protein Summary

The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 66-78 copies in cases of SCA12.

Alternative names and synonyms associated with PPP2R2B

  • protein phosphatase 2, regulatory subunit B, beta (PPP2R2B)
  • protein phosphatase 2, regulatory subunit B, alpha (ppp2r2a)
  • protein phosphatase 2, regulatory subunit B, beta (ppp2r2b)
  • protein phosphatase 2, regulatory subunit B, beta b (ppp2r2bb)
  • protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform (PPP2R2B)
  • protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform (Ppp2r2b)
  • protein phosphatase 2, regulatory subunit B, beta (Ppp2r2b)
  • 2900026H06Rik protein
  • 6330404L05Rik protein
  • B55BETA protein
  • E130009M08Rik protein
  • PP2A protein
  • PP2A-PR55B protein
  • PP2AB55BETA protein
  • PP2ABBETA protein
  • PP2APR55B protein
  • PP2APR55BETA protein
  • PPP2R2B protein
  • ppp2r2b-a protein
  • ppp2r2c protein
  • Pppr2b2 protein
  • PR2AB55BETA protein
  • PR2ABBETA protein
  • PR2APR55BETA protein
  • PR52B protein
  • PR55-BETA protein
  • PR55BETA protein
  • SCA12 protein
  • zgc:101861 protein

Protein level used designations for PPP2R2B

protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform , beta isoform of regulatory subunit B55, protein phosphatase 2 , serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform , protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform , protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform , PP2A subunit B isoform B55-beta , PP2A subunit B isoform PR55-beta , PP2A subunit B isoform R2-beta , PP2A subunit B isoform beta , PP2A, subunit B, B-beta isoform , PP2A, subunit B, B55-beta isoform , PP2A, subunit B, PR55-beta isoform , PP2A, subunit B, R2-beta isoform , protein phosphatase-2A subunit-beta , protein phosphatase 2, regulatory subunit B, beta , serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like , serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, beta isoform , serine/threonine protein phosphatase 2A, neuronal isoform , BRbeta B-regulatory subunit of protein phosphatase 2A , PP2A subunit B isoform BRB , PP2A, subunit B, BRB isoform , protein phosphatase 2A 55 kDa regulatory subunit, beta isoform , phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform

GENE ID SPECIES
416350 Gallus gallus
462170 Pan troglodytes
478053 Canis lupus familiaris
496486 Xenopus (Silurana) tropicalis
549212 Xenopus (Silurana) tropicalis
558810 Danio rerio
706988 Macaca mulatta
100009139 Oryctolagus cuniculus
100023749 Monodelphis domestica
100060957 Equus caballus
100174027 Pongo abelii
100407627 Callithrix jacchus
100584267 Nomascus leucogenys
72930 Mus musculus
5521 Homo sapiens
509290 Bos taurus
60660 Rattus norvegicus
397089 Sus scrofa
394301 Xenopus laevis
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