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Browse our PPP2R5A Proteins (PPP2R5A)

Full name:
Protein Phosphatase 2, Regulatory Subunit B', alpha Proteins (PPP2R5A)
On www.antibodies-online.com are 5 Protein Phosphatase 2, Regulatory Subunit B', alpha (PPP2R5A) Proteins from 2 different suppliers available. Additionally we are shipping PPP2R5A Antibodies (66) and many more products for this protein. A total of 78 PPP2R5A products are currently listed.
Synonyms:
B56A, PR61A, PR61alpha, si:dkey-18c8.1
list all proteins Gene Name GeneID UniProt
PPP2R5A 226849 Q6PD03
PPP2R5A 5525 Q15172
Rat PPP2R5A PPP2R5A 312754  

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PPP2R5A Proteins (PPP2R5A) by Origin

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More Proteins for PPP2R5A Interaction Partners

Mouse (Murine) Protein Phosphatase 2, Regulatory Subunit B', alpha (PPP2R5A) interaction partners

  1. in vivo expression of B56alpha suppressed parasympathetic regulation of heart rate and increased RyR2 phosphorylation in cardiomyocytes.

  2. Cardiomyocyte-directed overexpression of B56alpha, the main cardiac PP2A (show PPP2R2B Proteins) regulatory subunit, results in the dephosphorylation of myofilament proteins, increased Ca2 (show CA2 Proteins)+ sensitivity, and higher contractility.

  3. reversible phosphorylation of Dzip1 (show DZIP1 Proteins), which is controlled by the antagonistic action of CK2 (show CSNK2A1 Proteins) and B56-containing PP2As, has an important impact on the stability of Gli (show GLI1 Proteins) transcription factors and Hh signaling.

  4. Elevated B56alpha/PP2A (show PPP2R2B Proteins) inhibits hormone-sensitive lipase (show LIPE Proteins) and lipolysis in white adipose tissue of DIO mice.

  5. B56alpha has a role in nuclear export of the catalytic subunit of PP2A (show PPP2R2B Proteins)

  6. Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia.

Human Protein Phosphatase 2, Regulatory Subunit B', alpha (PPP2R5A) interaction partners

  1. results suggest that PKCalpha (show PKCa Proteins) can modify PP2A (show PPP2R4 Proteins) activity by phosphorylation of B56alpha at Ser (show SIGLEC1 Proteins)(41). This interplay between PKCalpha (show PKCa Proteins) and PP2A (show PPP2R4 Proteins) represents a new mechanism to regulate important cellular functions like cellular Ca(2 (show CA2 Proteins)+) homeostasis.

  2. PP2A (show PPP2R4 Proteins) regulatory subunit Balpha controls endothelial contractility and vessel lumen integrity via regulation of HDAC7 (show HDAC7 Proteins).

  3. Following TGF-beta1 (show TGFB1 Proteins) treatment, recruitment of PP2A (show PPP2R4 Proteins)-Balpha by TbetaRI (show TGFBR1 Proteins) increased in benign cells, but not in malignant cells. Inhibition of PP2A (show PPP2R4 Proteins) in benign cells resulted in an increase in ERK (show EPHB2 Proteins) activation and in TGF-beta1 (show TGFB1 Proteins) auto-induction after TGF-beta1 (show TGFB1 Proteins) treatment.

  4. reversible phosphorylation of Dzip1 (show DZIP1 Proteins), which is controlled by the antagonistic action of CK2 (show CSNK2A1 Proteins) and B56-containing PP2As, has an important impact on the stability of Gli (show GLI1 Proteins) transcription factors and Hh signaling.

  5. Reveal that PPP2R5A, an essential tumour suppressor, tunes the balance of phosphorylation to promote chromosome-spindle interactions during cell division.

  6. The PP2A (show PPP2R4 Proteins)-B'alpha holoenzyme appears to function as an important endogenous regulator of SK1.

  7. B56alpha has a role in nuclear export of the catalytic subunit of PP2A (show PPP2R4 Proteins)

  8. The B'alpha subunit of protein phosphatase 2A (PP 2A) as a CHK2 (show CHEK2 Proteins) binding partner shows that their interaction is modulated by DNA damage.

  9. PKR (show PKLR Proteins) regulates B56(alpha)-mediated BCL2 (show BCL2 Proteins) phosphatase activity in acute lymphoblastic leukemia-derived REH (show CES1 Proteins) cells.

  10. The B'alpha1 subunit of the serine/threonine protein phosphatase 2A, which binds to cyclin G1 (show CCNG1 Proteins), can stabilize cyclin G1 (show CCNG1 Proteins) under unstressed conditions and upon DNA damage, as well as inhibit the ability of cyclin G1 (show CCNG1 Proteins) to be ubiquitinated.

Xenopus laevis Protein Phosphatase 2, Regulatory Subunit B', alpha (PPP2R5A) interaction partners

  1. reversible phosphorylation of Dzip1 (show DZIP1 Proteins), which is controlled by the antagonistic action of CK2 (show CSNK2B Proteins) and B56-containing PP2As, has an important impact on the stability of Gli (show GLI1 Proteins) transcription factors and Hh signaling.

  2. Our data also suggest that B56alpha functions pre-midblastula transition , inhibiting Wnt (show WNT2 Proteins) signaling on the ventral side of the embryo, and again during organogenesis, while B56gamma functions primarily post-midblastula transition

PPP2R5A Protein Profile

Protein Summary

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with PPP2R5A

  • protein phosphatase 2, regulatory subunit B', alpha (PPP2R5A)
  • protein phosphatase 2, regulatory subunit B (B56), alpha isoform (Ppp2r5a)
  • protein phosphatase 2, regulatory subunit B', alpha (Ppp2r5a)
  • protein phosphatase 2, regulatory subunit B', alpha (ppp2r5a)
  • protein phosphatase 2, regulatory subunit B', alpha isoform (ppp2r5a)
  • B56A protein
  • PR61A protein
  • PR61alpha protein
  • si:dkey-18c8.1 protein

Protein level used designations for PPP2R5A

protein phosphatase 2, regulatory subunit B (B56), alpha isoform , protein phosphatase 2, regulatory subunit B', alpha isoform , serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform , protein phosphatase 2, regulatory subunit B', alpha , serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform-like , PP2A B subunit isoform B'-alpha , PP2A B subunit isoform B56-alpha , PP2A B subunit isoform PR61-alpha , PP2A B subunit isoform R5-alpha , PP2A, B subunit, B' alpha isoform , PP2A, B subunit, B56 alpha isoform , PP2A, B subunit, PR61 alpha isoform , PP2A, B subunit, R5 alpha isoform , PR61alpha , serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform , protein phosphatase 2A regulatory subunit B B56 alpha isoform , phosphatase regulatory subunit B56alpha

GENE ID SPECIES
457716 Pan troglodytes
716313 Macaca mulatta
100016488 Monodelphis domestica
100078692 Ornithorhynchus anatinus
100346997 Oryctolagus cuniculus
100411858 Callithrix jacchus
100448353 Pongo abelii
226849 Mus musculus
5525 Homo sapiens
490280 Canis lupus familiaris
100101925 Sus scrofa
533788 Bos taurus
312754 Rattus norvegicus
100137719 Xenopus laevis
421372 Gallus gallus
562460 Danio rerio
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