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anti-Mouse (Murine) Transportin 1 antibody for Enzyme Immunoassay

Recommended Transportin 1 Antibody (supplied by: Log in to see )

Antigen
Transportin 1 (TNPO1) Antibodies
  • ATTRN1
  • AU021749
  • D13Ertd688e
  • DKFZp469O204
  • F12A24.13
  • F12A24_13
  • IPO2
  • JC310
  • Kpnb2
  • KPNB2
  • MIP
  • MIP1
  • mip1
  • Mip1
  • SIN1
  • SIN1b
  • SIN1g
  • TNPO1
  • TRANSPORTIN 1
  • transportin 1
  • TRN
  • zgc:100858
  • Znf667
Epitope
Center
23
14
5
5
5
4
3
2
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
63
31
22
5
2
2
1
Host
Rabbit
62
9
3
Clonality
Polyclonal
Conjugate
This Transportin 1 antibody is un-conjugated
6
6
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
50
38
20
18
17
11
6
6
5
3
1
Supplier
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Catalog No. ABIN500232
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088361744 ABIN500230 EIA IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 4

Top referenced anti-Transportin 1 antibody for Enzyme Immunoassay

Similar anti-Transportin 1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 4 Antibodies 9 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 4 Antibodies
Immunofluorescence (IF) 2 Antibodies 4 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 2 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies 11 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Microarray (MA) 1 Antibodies
Western Blotting (WB) 11 Antibodies
Flow Cytometry (FACS) 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies

General

Antigen Transportin 1 (TNPO1) Antibodies
Epitope Center
(23), (14), (5), (5), (5), (4), (3), (2), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(63), (31), (22), (5), (2), (2), (1)
Host Rabbit
(62), (9), (3)
Clonality
Polyclonal
Conjugate This Transportin 1 antibody is un-conjugated
(6), (6), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(50), (38), (20), (18), (17), (11), (6), (6), (5), (3), (1)
Pubmed 4 references available
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Product Details anti-Transportin 1 Antibody

Target Details Transportin 1 Application Details Handling References for anti-Transportin 1 Antibody (ABIN500232) Images
Specificity This antibody detects MIP1 at center.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Peptide affinity chromatography
Immunogen MAPKAP1 antibody was raised against a 18 amino acid peptide from near the center of human MAPKAP1.
Isotype IgG

Target Details Transportin 1

Product Details anti-Transportin 1 Antibody Application Details Handling References for anti-Transportin 1 Antibody (ABIN500232) Images back to top
Antigen
Alternative Name MIP1 (TNPO1 Antibody Abstract)
Background MAPKAP1 was initially identified as the human homolog of S. pombe SIN1. Recent evidence has shown that it identical to Mip1, a protein that interacts with MEKK2, a member of the mitogen-activated protein kinase (MAPK) intracellular signaling network. MAPKAP1 is thought to prevent MEKK2 activation and dimerization by forming a complex with the inactive and non-phosphorylated MEKK2, thereby blocking the JNK1/2, ERK1/2, p38 and ERK5 MAPKs. MAPKAP1 has also been shown to play a role in the TOR signaling process, a pathway that is involved in controlling cell growth and proliferation in response to environmental cues such as nutrients, growth factors and hormones. Experiments showed that MAPKAP1 helped to maintain the TOR/rictor assembly but not the TOR/RAPTOR complex, which allowed specific phosphorylation of Akt, a kinase that is believed to couple the growth factor-PI3K signaling pathway to the nutrient-regulated TOR signaling pathway. Multiple alternatively spliced isoforms of MAPKAP1 have been identified.Synonyms: MAPKAP1, Mitogen-activated protein kinase 2-associated protein 1, SAPK-interacting protein 1, SIN1, Stress-activated map kinase-interacting protein 1, TORC2 subunit MAPKAP1, Target of rapamycin complex 2 subunit MAPKAP1, mSIN1
Gene ID 79109
NCBI Accession NP_001006618
UniProt Q9BPZ7
Pathways PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Transportin 1 Antibody Target Details Transportin 1 Handling References for anti-Transportin 1 Antibody (ABIN500232) Images back to top
Application Notes ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Transportin 1 Antibody Target Details Transportin 1 Application Details References for anti-Transportin 1 Antibody (ABIN500232) Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

References for anti-Transportin 1 Antibody (ABIN500232)

Product Details anti-Transportin 1 Antibody Target Details Transportin 1 Application Details Handling Images back to top
Background publications

Jacinto, Facchinetti, Liu, Soto, Wei, Jung, Huang, Qin, Su: "SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity." in: Cell, Vol. 127, Issue 1, pp. 125-37, 2006

Wullschleger, Loewith, Hall: "TOR signaling in growth and metabolism." in: Cell, Vol. 124, Issue 3, pp. 471-84, 2006

Cheng, Zhang, Kim, Zhao, Zhao, Su: "Mip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation." in: Molecular and cellular biology, Vol. 25, Issue 14, pp. 5955-64, 2005

Schroder, Cloonan, Bushell, Sculley: "Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene." in: Gene, Vol. 339, pp. 17-23, 2004

Images

Product Details anti-Transportin 1 Antibody Target Details Transportin 1 Application Details Handling References for anti-Transportin 1 Antibody (ABIN500232) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Transportin 1 antibody (TNPO1) (Center) (ABIN500232) Immunohistochemistry of MAPKAP1 in human skeletal muscle tissue with this product at ...
Western Blotting (WB) image for anti-Transportin 1 antibody (TNPO1) (Center) (ABIN500232) Western blot analysis of MAPKAP1 in human skeletal muscle tissue lysate with this pro...