Browse our anti-Inositol Polyphosphate Phosphatase-Like 1 (INPPL1) Antibodies

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anti-Inositol Polyphosphate Phosphatase-Like 1 Antibodies (INPPL1)
On www.antibodies-online.com are 79 Inositol Polyphosphate Phosphatase-Like 1 (INPPL1) Antibodies from 14 different suppliers available. Additionally we are shipping Inositol Polyphosphate Phosphatase-Like 1 Kits (3) and Inositol Polyphosphate Phosphatase-Like 1 Proteins (3) and many more products for this protein. A total of 91 Inositol Polyphosphate Phosphatase-Like 1 products are currently listed.
Synonyms:
51C, INPPL1, OPSMD, Ship2, si:bz46j2.7, si:rp71-46j2.7
list all antibodies Gene Name GeneID UniProt
INPPL1 3636 O15357
INPPL1 16332 Q6P549
INPPL1 65038 Q9WVR3

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Top referenced anti-Inositol Polyphosphate Phosphatase-Like 1 Antibodies

  1. Human Polyclonal INPPL1 Primary Antibody for ICC, IF - ABIN151139 : Yoshinaga, Ohkubo, Sasaki, Nuriya, Ogawa, Yasui, Tabata, Nakajima: A phosphatidylinositol lipids system, lamellipodin, and Ena/VASP regulate dynamic morphology of multipolar migrating cells in the developing cerebral cortex. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 (PubMed)

More Antibodies against Inositol Polyphosphate Phosphatase-Like 1 Interaction Partners

Zebrafish Inositol Polyphosphate Phosphatase-Like 1 (INPPL1) interaction partners

Human Inositol Polyphosphate Phosphatase-Like 1 (INPPL1) interaction partners

  1. article focuses on the mutations associated with opsismodysplasia and explores the role of INPPL1/ SHIP2 in skeletal development (Review)

  2. SHIP2 recruits Mena (show EGFR Antibodies) to invadopodia and disruption of SHIP2-Mena (show EGFR Antibodies) interaction in cancer cells leads to attenuated capacity for ECM (show MMRN1 Antibodies) degradation and invasion in vitro, as well as reduced metastasis in vivo.

  3. In glioblastoma 1321 N1 cells, we recently identified Myo1c (show MYO1C Antibodies) as a new interactor of SHIP2. SHIP2 localization at lamellipodia and ruffles is impaired in Myo1c (show MYO1C Antibodies) depleted cells. In the absence of Myo1c (show MYO1C Antibodies), N1 cells tend to associate to form clusters.

  4. decreased expression of transcription factor Sp1 (show SP1 Antibodies) contributes to suppression of SHIP2 in gastric cancer cells.

  5. In order to shed light on the role of the C2 related (C2R) domain, immediately C-terminal to the SHIP2 phosphatase domain, molecular cloning, expression, purification and crystallization of the human SHIP2 fragment containing the phosphatase (Ptase) and C2R domains were performed an X-ray crystallographic data analysis was conducted.

  6. Regulation of phosphatidylinositol 4,5-bisphosphate by SHIP2 controls glioblastoma cell migration through the organization of focal adhesions.

  7. the dissociation process of the EphA2 (show EPHA2 Antibodies)-SHIP2 SAM-SAM (show TTN Antibodies) domain heterodimer complex the dissociation process of the EphA2 (show EPHA2 Antibodies)-SHIP2 SAM-SAM (show TTN Antibodies) domain heterodimer complex

  8. Suppression of SHIP2 contributes to tumorigenesis and proliferation of gastric cancer cells via activation of Akt (show AKT1 Antibodies).

  9. these findings suggest that SHIP2 is an important regulator of hepatic lipogenesis and lipoprotein secretion in insulin (show INS Antibodies) resistance state.

  10. investigated the molecular link between SHIP2 expression and metabolic dyslipidemia using overexpression or suppression of SHIP2 gene in HepG2 cells

Mouse (Murine) Inositol Polyphosphate Phosphatase-Like 1 (INPPL1) interaction partners

  1. These findings suggest that palmitate contributes to SHIP2 overexpression in skeletal muscle via the mechanisms involving the activation of ceramide-JNK (show MAPK8 Antibodies) and NF-kappaB (show NFKB1 Antibodies) pathways.

  2. results suggest that SHIP2 contributes to the regulation of food intake mainly via the attenuation of insulin (show INS Antibodies) signalling in the hypothalamus of mice

  3. The catalytically-inactive Ship2 mutant protein in a context of reduced PtdIns(4,5)P2 3-kinase activity.

  4. Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).

  5. These results suggest that SHIP2 is a potent negative regulator of insulin (show INS Antibodies)/IGF-I (show IGF1 Antibodies) actions in the brain, and excess amounts of SHIP2 may be related, at least in part, to brain dysfunction in insulin (show INS Antibodies) resistance with type 2 diabetes.

  6. The SHIP2 is a negative regulator of insulin (show INS Antibodies) signaling, our findings suggest the importance of the phosphoinositide metabolism at endocytic clathrin-coated pits in the regulation of insulin (show INS Antibodies) signal output.

  7. Association with the insulin (show INS Antibodies) resistance of diabetic db/db (show LEPR Antibodies) mice.

  8. The role of SHIP2 in controlling phosphatidylinositol 3,4,5-trisphosphate levels in platelets.

  9. SH2-containing inositol phosphatase 2 predominantly regulates Akt2 (show AKT2 Antibodies), and not Akt1 (show AKT1 Antibodies), phosphorylation at the plasma membrane in response to insulin (show INS Antibodies) in adipocytes

  10. SHIP2 plays an important role in the negative regulation of insulin (show INS Antibodies) signaling for protein synthesis and the impact of SHIP2 is altered, dependent on the acute or chronic exposure of excess concentrations of amino acids in culture.

Pig (Porcine) Inositol Polyphosphate Phosphatase-Like 1 (INPPL1) interaction partners

  1. we suggest that SHIP2 might play a role in the regulation of skeletal muscle development in pigs

Inositol Polyphosphate Phosphatase-Like 1 (INPPL1) Antigen Profile

Antigen Summary

The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.

Alternative names and synonyms associated with Inositol Polyphosphate Phosphatase-Like 1 (INPPL1)

  • inositol polyphosphate phosphatase-like 1b (inppl1b) antibody
  • inositol polyphosphate phosphatase-like 1 (INPPL1) antibody
  • inositol polyphosphate phosphatase-like 1 (LOC100339369) antibody
  • phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1-like (LOC100180571) antibody
  • inositol polyphosphate phosphatase-like 1 (Inppl1) antibody
  • 51C antibody
  • INPPL1 antibody
  • OPSMD antibody
  • Ship2 antibody
  • si:bz46j2.7 antibody
  • si:rp71-46j2.7 antibody

Protein level used designations for INPPL1

SH2-domain-containing inositol 5-phosphatase 2b , inositol polyphosphate phosphatase-like 1 , ship2b , phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2-like , 51C protein , INPPL-1 , SH2 domain-containing inositol 5'-phosphatase 2 , SH2 domain-containing inositol-5'-phosphatase 2 , SHIP-2 , phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 , phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 , protein 51C , SH2 domain-containing inositol phosphatase 2 , ablSH3-binding protein , inositol polyphosphate phosphatase-like protein 1 , SH2-containing inositol phosphatase 2

GENE ID SPECIES
368433 Danio rerio
428692 Gallus gallus
451403 Pan troglodytes
100339369 Oryctolagus cuniculus
100482460 Ailuropoda melanoleuca
100180571 Ciona intestinalis
100596562 Nomascus leucogenys
3636 Homo sapiens
16332 Mus musculus
65038 Rattus norvegicus
485209 Canis lupus familiaris
783833 Bos taurus
100462718 Sus scrofa
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