Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Rat (Rattus) PLEKHA1 Antibodies:
anti-Human PLEKHA1 Antibodies:
anti-Mouse (Murine) PLEKHA1 Antibodies:
Go to our pre-filtered search.
Human Polyclonal PLEKHA1 Primary Antibody for ICC, IF - ABIN4357827
Sun, Zhao, McGreal, Cohen-Tayar, Rockowitz, Wilczek, Ashery-Padan, Shechter, Zheng, Cvekl: Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers. in Epigenetics & chromatin 2016
Studies indicate that the high-risk allele of the 10q26 locus encompasses three genes, PLEKHA1, ARMS2 (show ARMS2 Antibodies), and HTRA1 (show HTRA1 Antibodies) with high linkage disequilibrium.
CX3CR1 (show CX3CR1 Antibodies) (T280M and V249I) and PLEKHA1 (A320T) polymorphisms were not found to be associated with age-related macular degeneration in an Indian population.
This study provides evidence of the joint contribution of genetic variants in PLEKHA1/ARMS2 (show ARMS2 Antibodies)/HTRA1 (show HTRA1 Antibodies) to age-related macular degeneration risk.
TAPP1 binds to protein tyrosine phosphatase PTPL1 (show PTPN13 Antibodies).
syntrophins regulate the localization of TAPP1, which may be important for remodeling the actin cytoskeleton in response to growth factor stimulation
PLEKHA1 is strongly implicated as primarily responsible for the evidence of linkage of age-related maculopathy (ARM) to the 10q26 locus and as a major contributor to ARM.susceptibility.
Although a role for PLEKHA1 could not be totally excluded, there was a four times higher age-related macular degeneration risk was associated with haplotype "A-T-A" involving "PLEKHA1-LOC387715-HTRA1 (show HTRA1 Antibodies)" risk alleles.
Independent of CFH (show CFH Antibodies) genotype or smoking history, an individual's risk of AMD (show AMD1 Antibodies) (age-related macular degeneration) could be increased or decreased, depending on their genotype or haplotype in the 10q26 region.
this study shows that TAPP1/2 double knock-out mice develop chronic germinal centers with age and show abnormal expression of B-cell activation (show BLNK Antibodies) anddevelop lupus-like characteristics including anti-DNA antibodies and deposition of immune complexes in kidneys
Results identify TAPP1 as an important negative regulator of oligodendrocyte precursor cells differentiation through the Mek (show MDK Antibodies)/Erk (show EPHB2 Antibodies) signaling pathway.
interacts with phosphatidylinositol (3,4)-bisphosphate thus regulating B-cell activation (show BLNK Antibodies) and autoantibody production
This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.
pleckstrin homology domain-containing family A member 1
, pleckstrin homology domain-containing protein family A member 1
, tandem PH domain containing protein-1
, pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
, tandem PH domain-containing protein 1
, PH domain-containing family A member 1