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Results indicate that EGR-1 is a transcriptional regulator of MTCH1 and give some clues about the cellular processes in which MTCH1 might participate.
Mtch1 antibody positive neuro-Bechet's disease patients had more attacks, increased disability and lower serum nucleosome levels.
Compares and contrasts all the known human SLC25A (show SLC25A25 Proteins)* genes and includes functional information.
Data indicate that the formation of cytochrome c (show CYCS Proteins)-Apaf-1 (show APAF1 Proteins) apoptosome and the presence of Smac (show DIABLO Proteins) are absolutely required for PSAP (show PSAP Proteins)-induced apoptosis.
mitochondrial localization and proapoptotic activity of PSAP (show PSAP Proteins) suggest that it is an important regulator of apoptosis
PSAP (show PSAP Proteins) has two proapoptotic isoforms generated by alternative splicing, and both proteins are imported into the mitochondrial outer membrane using multiple internal targeting signals, and both contain two proapoptotic domains.
Data show that all PSAP (show PSAP Proteins) splicing isoforms are localized in the mitochondria and are pro-apoptotic.
This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
cell proliferation-inducing protein 60
, mitochondrial carrier homolog 1
, presenilin-associated protein
, solute carrier family 25, member 49
, mitochondrial carrier-like protein 1