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Programmed Cell Death 6 ELISA Kits (PDCD6)
On are 5 Programmed Cell Death 6 (PDCD6) ELISA Kits from 4 different suppliers available. Additionally we are shipping PDCD6 Antibodies (82) and PDCD6 Proteins (16) and many more products for this protein. A total of 105 PDCD6 products are currently listed.
alg-2, Alg2, AV299538, MA-3, MGC52821, MGC132114, PDCD6, PEF1B, PS2, zgc:63952
list all ELISA KIts Gene Name GeneID UniProt
PDCD6 10016 O75340
Mouse PDCD6 PDCD6 18570 P12815
Rat PDCD6 PDCD6 308061  

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Human Programmed Cell Death 6 (PDCD6) interaction partners

  1. The gene copy numbers and mRNA levels for both ALG-2 and HEBP2 are significantly upregulated in breast and lung cancer. Coexpression of ALG-2 and HEBP2 markedly increases the cytoplasmic pool of ALG-2 and alters the subcellular distribution of HEBP2. Abnormalities in the ALG-2/HEBP2 interaction impairs spindle orientation and positioning during mitosis.

  2. The results suggest that ALG-2 acts as a Ca2 (show CA2 ELISA Kits)+-sensitive adaptor to concentrate and polymerize TFG at endoplasmic reticulum exit sites, supporting a potential role for ALG-2 in COPII-dependent trafficking from the endoplasmic reticulum.

  3. ALG2 has a tumor suppressive role in glioblastoma and might be a potential target for the treatment of glioblastoma.

  4. miR (show MLXIP ELISA Kits)-183 may function as an oncogene (show RAB1A ELISA Kits) and may enhance cell proliferation by targeting PDCD6, implying a potential therapeutic target for this malignancy.

  5. Our results suggest that PDCD6 may play an important role in the pathogenesis of cervical squamous cell carcinoma

  6. PDCD6 may represent a biomarker candidate gene that could help to identify a group of patients at high risk for recurrence and death.

  7. Palmitoylation sites and the N-terminal Pro-rich region were necessary for efficient secretion, but ABSs (ALG-2-binding sites) were dispensable.

  8. The present study provided evidence that rs4957014 and rs3756712 are associated with Uterine leiomyoma (UL) risk, the results indicated that genetic polymorphisms in PDCD6 may contribute to the development of UL.

  9. CHERP and ALG-2 participate in regulation of alternative splicing of IP3R1 (show ITPR1 ELISA Kits) pre-mRNA and provide new insights into post-transcriptional regulation of splicing variants in Ca(2 (show CA2 ELISA Kits)+) signaling pathways.

  10. the binding of ALG-2 to IST1 (show IST1 ELISA Kits) is Ca(2 (show CA2 ELISA Kits)+)-dependent

Mouse (Murine) Programmed Cell Death 6 (PDCD6) interaction partners

  1. ALG2 regulates glioblastoma cell proliferation, migration and tumorigenicity.

  2. Substitution of either L52 with Ala or F148 with Ser (show SIGLEC1 ELISA Kits) of ALG-2 caused loss of binding abilities to PLSCR3 (show PLSCR3 ELISA Kits) lacking type 1 motif but retained those to PLSCR3 (show PLSCR3 ELISA Kits) lacking type 2 motif

  3. ALG-2 is physiologically dispensable for apoptotic responses (ALG-2 protein)

PDCD6 Antigen Profile

Antigen Summary

This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

Alternative names and synonyms associated with PDCD6

  • programmed cell death 6 (pdcd6) Elisa Kit
  • programmed cell death 6 (PDCD6) Elisa Kit
  • programmed cell death 6 (Pdcd6) Elisa Kit
  • alg-2 Elisa Kit
  • Alg2 Elisa Kit
  • AV299538 Elisa Kit
  • MA-3 Elisa Kit
  • MGC52821 Elisa Kit
  • MGC132114 Elisa Kit
  • PDCD6 Elisa Kit
  • PEF1B Elisa Kit
  • PS2 Elisa Kit
  • zgc:63952 Elisa Kit

Protein level used designations for PDCD6

programmed cell death 6 , programmed cell death protein 6 , apoptosis-linked gene 2 protein , probable calcium-binding protein ALG-2 , ALG-257 , PMP41

380264 Xenopus laevis
393925 Danio rerio
723039 Macaca mulatta
10016 Homo sapiens
18570 Mus musculus
420988 Gallus gallus
609549 Canis lupus familiaris
100125927 Bos taurus
308061 Rattus norvegicus
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