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SUMO1/sentrin Specific Peptidase 1 ELISA Kits (SENP1)
On are 3 SUMO1/sentrin Specific Peptidase 1 (SENP1) ELISA Kits from 3 different suppliers available. Additionally we are shipping SENP1 Antibodies (107) and SENP1 Proteins (4) and many more products for this protein. A total of 121 SENP1 products are currently listed.
2310046A20Rik, D15Ertd528e, E330036L07Rik, senp1, senp1a, senp1b, suPr-2, xsenp1
list all ELISA KIts Gene Name GeneID UniProt
SENP1 29843 Q9P0U3
SENP1 223870 P59110
Rat SENP1 SENP1 300193  

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Xenopus laevis SUMO1/sentrin Specific Peptidase 1 (SENP1) interaction partners

  1. XSENP1a and XSENP1b are sumo-specific proteases that inhibit normal head formation by inhibiting Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling.

Human SUMO1/sentrin Specific Peptidase 1 (SENP1) interaction partners

  1. GATA1 (show GATA1 ELISA Kits) is an essential downstream target of SENP1 and that the differential expression and response of GATA1 (show GATA1 ELISA Kits) and Bcl-xL (show BCL2L1 ELISA Kits) are a key mechanism underlying chronic mountain sickness pathology.

  2. miRNA1236 regulates hypoxia-induced epithelial-mesenchymal transformation and metastasis by repressing HDAC3 (show HDAC3 ELISA Kits) and SENP1 expression.

  3. SENP1 deSUMOylated SMAD4 (show SMAD4 ELISA Kits) to promote EMT (show ITK ELISA Kits) via up-regulating E-cadherin (show CDH1 ELISA Kits) in prostate cancer cells. Therefore, SENP1 is a potential target for treatment of advanced prostate cancer.

  4. The variability of the SENP1 and SENP2 genes may play a role in breast cancer occurrence.

  5. this study elucidated that SENP1 is essential for triple-negative breast cancer cell proliferation and migration in vitro, as well as tumor formation and metastasis in vivo

  6. Hepatocellular carcinoma cells express a high level of Senp1 which is induced by HGF/c-Met signals. Senp1 silencing reduces the HGF (show HGF ELISA Kits)-induced proliferation and migration of HCC (show FAM126A ELISA Kits) cells, induces HCC (show FAM126A ELISA Kits) cell apoptosis and growth arrest, and epithelial-to-mesenchymal transition, with increase of E-cadherin (show CDH1 ELISA Kits) and ZO-1 (show TJP1 ELISA Kits) expression, decrease of fibronectin (show FN1 ELISA Kits) and N-cadherin (show CDH2 ELISA Kits) expression.

  7. a significant role of SENP1 in the regulation of cell migration and invasion in neuroblastoma (show ARHGEF16 ELISA Kits)

  8. A key role for SENP1 in astrocytoma development and apoptosis.SENP1 inhibition promotes cell apoptosis by regulating NF-kappa B (show NFKB1 ELISA Kits)/Akt (show AKT1 ELISA Kits) signaling pathways.

  9. Genetic interactions of SNPs in CARD14 (show CARD14 ELISA Kits), SENP1 and VEGFA (show VEGFA ELISA Kits) might represent a functional mechanism in the pathogenesis of high altitude polycythemia.

  10. SENP1 desensitizes hypoxic ovarian cancer cells to cisplatin by up-regulating HIF-1alpha (show HIF1A ELISA Kits)

Mouse (Murine) SUMO1/sentrin Specific Peptidase 1 (SENP1) interaction partners

  1. a novel negative feedback loop mediated by STAT3 (show STAT3 ELISA Kits)-SOCS3 (show SOCS3 ELISA Kits), which is tightly controlled by SENP1 via de-SUMOylation of protein tyrosine phosphatase 1B (PTP1B (show PTPN1 ELISA Kits)), in IFN-gamma (show IFNG ELISA Kits) signaling, is reported.

  2. SENP1 deletion in adipocytes causes Type 1 diabetes mellitus via enhanced SUMOylation of NEMO (show IKBKG ELISA Kits), leading to increased NF-kappaB (show NFKB1 ELISA Kits) activity, cytokine production and pancreatic inflammation.

  3. results of the present study are of both theoretical and therapeutic significance to explore the potential roles of SENP1 under IH condition and elucidated the mechanisms underlying microglial survival and activation

  4. A role for islet SENP1 as a regulator of in vivo glucose homeostasis was demonstrated by the tissue-selective and inducible knockout of this enzyme.

  5. SENP1 up-regulation in diseased heart is mediated via calcineurin (show PPP3CA ELISA Kits)-NFAT (show NFATC1 ELISA Kits)/MEF2C (show MEF2C ELISA Kits)-PGC-1alpha (show PPARGC1A ELISA Kits) pathway.

  6. SENP1 deficiency exacerbates ischemia-reperfusion injury in cardiomyocytes via a HIF1alpha (show HIF1A ELISA Kits)-dependent pathway.

  7. SENP1 enhances adipogenesis through de-SUMOylation of Sharp-1 (show BHLHE41 ELISA Kits), which then releases Sharp-1 (show BHLHE41 ELISA Kits) repression of PPARgamma (show PPARG ELISA Kits) expression and adipocyte differentiation. These results reveal SENP1 as a novel regulator in adipogenesis.

  8. Senp1 Is the Primary Activity for Desumoylation of Sumo1 (show SUMO1 ELISA Kits)-Modified Proteins.

  9. SENP1 is a specific SUMO protease to regulate SUMOylation status of PGC-1alpha (show PPARGC1A ELISA Kits).

  10. SENP1 is essential for cell survival during endoplasmic reticulum stress.

SENP1 Antigen Profile

Antigen Summary

This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with SENP1

  • SUMO1/sentrin specific peptidase 1 (SENP1) Elisa Kit
  • sentrin/SUMO-specific protease 1 (Senp1) Elisa Kit
  • similar to Sentrin-specific protease 1 (Sentrin/SUMO-specific protease SENP1) (SENP1) Elisa Kit
  • SUMO1/sentrin specific peptidase 1 (senp1-b) Elisa Kit
  • SUMO1/sentrin specific peptidase 1 (senp1) Elisa Kit
  • SUMO1/sentrin specific peptidase 1 (Senp1) Elisa Kit
  • SUMO1/sentrin specific peptidase 1 (senp1-a) Elisa Kit
  • 2310046A20Rik Elisa Kit
  • D15Ertd528e Elisa Kit
  • E330036L07Rik Elisa Kit
  • senp1 Elisa Kit
  • senp1a Elisa Kit
  • senp1b Elisa Kit
  • suPr-2 Elisa Kit
  • xsenp1 Elisa Kit

Protein level used designations for SENP1

sentrin-specific protease 1 , SUMO1/sentrin specific peptidase 1 , sentrin/SUMO-specific protease 1 , similar to Sentrin-specific protease 1 (Sentrin/SUMO-specific protease SENP1) , sentrin/SUMO-specific protease SENP1 , sentrin specific protease 1b , SUMO1/sentrin specific protease 1 , SUMO-1 protease 2 , SUMO-specific protease U1p1 , sentrin specific protease 1a , Sumo1/sentrin/SMT3 specific peptidase 1

477629 Canis lupus familiaris
538091 Bos taurus
100157986 Sus scrofa
426185 Gallus gallus
451862 Pan troglodytes
548976 Xenopus (Silurana) tropicalis
707603 Macaca mulatta
714066 Macaca mulatta
100056855 Equus caballus
100190851 Pongo abelii
100329216 Xenopus laevis
100547302 Meleagris gallopavo
100553998 Anolis carolinensis
29843 Homo sapiens
223870 Mus musculus
398517 Xenopus laevis
300193 Rattus norvegicus
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