Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
a comprehensive model of CCL19 and CCL21 (show CCL21 Proteins) transport and gradient formation in the lymph nodes (LNs) was built; predicts that ACKR4 in LNs prevents CCL19/CCL21 (show CCL21 Proteins) accumulation in efferent lymph, but does not control intranodal gradients; instead, it attributes the disrupted interfollicular CCL21 (show CCL21 Proteins) gradients observed in Ackr4-deficient LNs to ACKR4 loss upstream
The beneficial effects of epicatechin in ameriorating diet-induced obesity and insulin (show INS Proteins) resistance could be mediated, at least in part, by marked suppression of CCL19 expression.
Results suggest that baicalin exerts an inhibitory effect on airway inflammation, and this effect may be associated with the inhibition of CCR7 (show CCR7 Proteins) and its ligands, CCL19 and CCL21 (show CCL21 Proteins), as well as on the nuclear factor-Kappa B (NF-kappaB (show NFKB1 Proteins)) pathway in a mouse model of asthma.
Interferon-gamma (IFN-gamma (show IFNG Proteins)) and interleukin-12 (IL-12 (show IL12A Proteins)) levels in the tumors and plasma were significantly enhanced after processing with recombinant mouse CCL19.
Modulation of the chemokines CCL19 and CCL21 (show CCL21 Proteins) represents a potent immunoregulatory treatment approach, and thus represents a novel therapeutic target to stabilize atherosclerotic lesions.
CCL19 (ELC) improves TH1 (show HAND1 Proteins)-polarized immune responses and protective immunity in a murine Her2/neu (show ERBB2 Proteins) DNA vaccination model.
study shows that CCL19/21 and its possible signaling through CXCR3 (show CXCR3 Proteins) are required for the development of thymic metallophilic macrophages
CCL19 and CCL21 (show CCL21 Proteins) induce prompt Ab responses to antigen, and negatively regulate helper T cell responses in vivo.
CCX-CKR (show CCRL1 Proteins)(-/-) have a 5-fold increase in the level of CCL21 (show CCL21 Proteins) protein in blood, and 2- to 3-fold increases in CCL19 and CCL21 (show CCL21 Proteins) in peripheral lymph nodes.
findings connect NOTCH1 (show NOTCH1 Proteins), DUSP22 (show DUSP22 Proteins), and CCL19-driven chemotaxis within a single functional network, suggesting that modulation of the homing process may provide a relevant contribution to the unfavorable prognosis associated with NOTCH1 (show NOTCH1 Proteins) mutations in CLL.
Deletion of this extended C-terminus reduces CCL21 (show CCL21 Proteins)'s affinity for heparin and transferring the CCL21 (show CCL21 Proteins) C-terminus to CCL19 enhances heparin binding mainly through non-specific, electrostatic interactions
CCL19 is significantly overexpressed in patients with unstable carotid atherosclerotic plaques and may be a possible novel biomarker for identifying high-risk patients in whom more urgent intervention may be indicated.
CrkL (show CRKL Proteins) regulates CCL19 and CCR7 (show CCR7 Proteins)-induced epithelial-to-mesenchymal transition via ERK (show EPHB2 Proteins) signaling pathway in epithelial ovarian carcinoma patients.
observed significantly higher concentrations of IL-8 (show IL8 Proteins) (p < 0.001), MCP-1 (show CCL2 Proteins) (p = 0.014), and MIP (show TNPO1 Proteins)-3beta (p = 0.022) in the PF of women with endometriosis than in the controls.
The solution structure of CCL19 is reported. It contains a canonical chemokine (show CCL1 Proteins) domain. Chemical shift mapping shows the N-termini of PSGL-1 (show SELPLG Proteins) and CCR7 (show CCR7 Proteins) have overlapping binding sites for CCL19 and binding is competitive.
Our findings serve to elucidate the molecular mechanisms underlying the resistin (show RETN Proteins) induction of CCL19 expression in ECs and the shear-stress protection against this induction.
The mRNA levels of CCL19/CCL21 (show CCL21 Proteins) in ankylosing spondylitis hip ligament were significantly higher than in osteoarthritis ligament.
Serum CCL19 and CCL21 (show CCL21 Proteins) were up-regulated during Rickettsia conorii infection.
CCL19 promoted monocyte adhesion to HUVEC cells. CCL19 rs2227302 was associated with coronary artery disease in a Chinese Han population.
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7.
C-C motif chemokine 19
, chemokine (C-C motif) ligand 19
, CCL19 chemokine
, CC chemokine ligand 19
, small inducible cytokine A19
, chemokine CCL19/MIP-3BETA
, CK beta-11
, EBI1 ligand chemokine
, EBI1-ligand chemokine
, beta chemokine exodus-3
, beta-chemokine exodus-3
, epstein-Barr virus-induced molecule 1 ligand chemokine
, macrophage inflammatory protein 3 beta
, macrophage inflammatory protein 3-beta
, small inducible cytokine subfamily A (Cys-Cys), member 19
, small-inducible cytokine A19
, EBI-1 ligand chemokine
, EBV-induced molecule 1 ligand chemokine
, chemokine CCL19