Browse our Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) ELISA Kits

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Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) ELISA Kits (HIF1A)
On www.antibodies-online.com are 77 Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) ELISA Kits from 17 different suppliers available. Additionally we are shipping Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) Antibodies (658) and Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) Proteins (50) and many more products for this protein. A total of 799 Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) products are currently listed.
Synonyms:
AA959795, bHLHe78, hif-1a, HIF-1alpha, HIF1, HIF1-alpha, hif1a, HIF1alpha, MOP1, PASD8
list all ELISA KIts Gene Name GeneID UniProt
HIF1A 15251 Q61221
HIF1A 3091 Q16665
HIF1A 29560 O35800

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Top referenced Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) ELISA Kits

  1. Mouse (Murine) HIF1A ELISA Kit for Sandwich ELISA - ABIN424082 : Du, Lin, Wang, Zhang, Wu, Lu, Ji, Yu: Quercetin greatly improved therapeutic index of doxorubicin against 4T1 breast cancer by its opposing effects on HIF-1? in tumor and normal cells. in Cancer chemotherapy and pharmacology 2011 (PubMed)
    Show all 3 references for 424082

  2. Rat (Rattus) HIF1A ELISA Kit for Sandwich ELISA - ABIN368077 : Rodríguez-Gómez, Banegas, Wangensteen, Quesada, Jiménez, Gómez-Morales, OValle, Duarte, Vargas: Influence of thyroid state on cardiac and renal capillary density and glomerular morphology in rats. in The Journal of endocrinology 2013 (PubMed)
    Show all 3 references for 368077

  3. Human HIF1A ELISA Kit for Sandwich ELISA - ABIN366532 : Jiang, Tang, Guo, Jiao: The role of insulin-like growth factor I and hypoxia inducible factor 1α in vascular endothelial growth factor expression in type 2 diabetes. in Annals of clinical and laboratory science 2013 (PubMed)
    Show all 3 references for 366532

  4. Pig (Porcine) HIF1A ELISA Kit for Sandwich ELISA - ABIN368480 : Gyöngyösi, Hemetsberger, Posa, Charwat, Pavo, Petnehazy, Petrasi, Pavo, Hemetsberger, Benedek, Benedek, Benedek, Kovacs, Kaun, Maurer: Hypoxia-inducible factor 1-alpha release after intracoronary versus intramyocardial stem cell therapy in myocardial infarction. in Journal of cardiovascular translational research 2010 (PubMed)

More ELISA Kits for Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) Interaction Partners

Mouse (Murine) Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) interaction partners

  1. in neurons HIF-1 and HIF-2 have redundant functions for cellular survival under ischemic conditions. By contrast, lack of anti-survival factors in Hif1a/Hif2a (show EPAS1 ELISA Kits)-deficient mice might protect from early acute neuronal cell death and neurological impairment, indicating a benefit of HIF-pathway inhibition in neurons in the very acute phase after ischemic stroke

  2. These results demonstrate that HIF-1alpha is critical for controlling the progression of infection with the fungal pathogen H. capsulatum by limiting IL-10 (show IL10 ELISA Kits).

  3. data illustrate that Hypoxia-inducible factor-1alpha (HIF-1alpha) is required for optimal innate leishmanicidal immune responses and, thereby, contributes to the cure of cutaneous leishmaniasis

  4. Hif1a expression is increased in myocardium/skeletal muscle of colonic adenocarcinoma-bearing mice.

  5. Despite the hypoxic nature of the bone marrow microenvironment, Hif-1alpha is dispensable for cell-autonomous Hematopoietic stem cell maintenance.

  6. we have identified HIF-1alpha as a novel regulator of IFN-gamma (show IFNG ELISA Kits)-dependent immunity that coordinates an immunometabolic program essential for control of M. tuberculosis infection in vitro and in vivo.

  7. Treatment of ES cells with TPO (show THPO ELISA Kits) induced the autocrine production of BMP4 (show BMP4 ELISA Kits) with concomitant upregulation of the BMP receptor BMPR1A (show BMPR1A ELISA Kits), phosphorylation of SMAD1 (show SMAD1 ELISA Kits), 5, 8, and activation of specific BMP4 (show BMP4 ELISA Kits) target genes; this was mediated by TPO (show THPO ELISA Kits)-dependent binding of transcription factor HIF-1alpha to the BMP4 (show BMP4 ELISA Kits) gene promoter.

  8. p-mTOR, p-4EBP1, HIF-1alpha and VEGF together are involved in the pathogenesis of asthma.

  9. Loss of HIF1A is associated with Development of Liver Fibrosis.

  10. HIF-1alpha deficiency attenuates spontaneous cardiomyogenesis through the negative regulation of endoderm development in mouse embryonic stem cells differentiating in vitro.

Human Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) interaction partners

  1. HIF-1alpha plays a critical role in the development of Wilms tumor.

  2. Hypoxia induced a significant increase of expression and secretion of VEGF and accumulation of HIF-1alpha protein in RPE cells

  3. we present evidence for a major role played by HIF-1a, through ROS (show ROS1 ELISA Kits) production, in the resistance of HNSCC and related CSCs in response to photon as well as carbon ion irradiation under hypoxia.

  4. phosphorylation by ERK (show EPHB2 ELISA Kits) also regulates the association of HIF-1alpha with a so-far-unknown interaction partner identified as mortalin (show HSPA9 ELISA Kits) (also known as GRP75 (show HSPA9 ELISA Kits) and HSPA9 (show HSPA9 ELISA Kits)), which mediates non-genomic involvement of HIF-1alpha in apoptosis.

  5. Genetic variants in HIF-1alpha and PHD2 (show EGLN1 ELISA Kits) genes exist in Caucasians but do not appear to alter 30-day mortality in sepsis

  6. Epstein Barr virus LMP1 (show PDLIM7 ELISA Kits) directly up-regulates HIF-1A transcription and post-transcription in nasopharyngeal carcinoma cells.

  7. Patients with hypoxia inducible factor 1 alpha overexpression had poor differentiation, increased depth of tumor invasion, more lymph node metastasis, and late pathological tumor-node-metastasis stage. Hypoxia inducible factor 1 alpha could be an indicator for differentiation, T classification, lymph node metastasis, and pathological tumor-node-metastasis stage, and it is worth further study

  8. These results also suggest that inhibition of HIF-1a with 2-MeOE2 sensitizes radioresistant melanoma cells 435R to X-ray irradiation through targeting the glycolysis that is regulated by PDK1 (show PDK1 ELISA Kits)

  9. High HIF1A expression is associated with Radioresistance in Glioblastoma.

  10. HIF1A mRNA overexpression can be regarded as a promising, independent molecular biomarker of unfavorable prognosis in CLL.

Pig (Porcine) Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) interaction partners

  1. a high expression of hypoxia induced factor-1a (HIF-1a) and heat shock protein 70 (HSP70 (show HSP70 ELISA Kits)) was noted

  2. Induction of ischemic osteonecrosis results in IL-6 (show IL6 ELISA Kits) production in the articular cartilage through an HIF-1-dependent pathway.

  3. Upregulation of VEGF (show VEGFA ELISA Kits) during hypoxia in chondrocyte is mediated partially through HIF-1alpha.

  4. HIF-1alpha activates Sox9 (show SOX9 ELISA Kits) expression and enhances Sox9 (show SOX9 ELISA Kits)-mediated transcriptional activity.

  5. Intramyocardial delivery of mesenchymal stem cells seems to trigger the release of angiogenic HIF-1alpha more effectively than does intracoronary delivery.

  6. immunostaining for HIF-1alpha and HIF-2alpha (show EPAS1 ELISA Kits) was observed during endochondral ossification, whereas only HIF-2alpha (show EPAS1 ELISA Kits) was present at sites of intramembranous ossification

  7. Downregulation of miR (show MYLIP ELISA Kits)-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 (show SIRT1 ELISA Kits) and recapitulates hypoxia preconditioning in cardiac myocytes.

  8. Viable chondrocytes in the superficial layer of the epiphyseal cartilage showed HIF-1alpha activation and VEGF upregulation with subsequent revascularization occurring in the cartilage.

Cow (Bovine) Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) interaction partners

  1. inverse expression and localization pattern of HIF1A and vasohibins during different stages of ovarian function in cow

  2. Hypoxia increased the amounts of HIF1A protein, VEGF mRNA and VEGF protein in cultured bovine luteal cells.

  3. hypoxia-induced changes in vascular cell growth are altered by hyperglycemia via inhibition of HIF-1alpha expression and activity

  4. VEGF has an effect on the expression of its own transcription factor, HIF-1, and on VEGF itself

  5. Identify sphingosine-1-phosphate as a novel and potent nonhypoxic activator of HIF-1.

Rabbit Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) interaction partners

  1. Suggest supplemental oxygen inhibits HIF-1alpha/VEGF signaling to reduce smooth muscle proliferation in rabbit arteriovenous fistula model.

  2. HIF-1alpha-induced HSP70 (show HSP70 ELISA Kits) overexpression increased the expression levels of ECM (show MMRN1 ELISA Kits) genes and cell viability, and protected chondrocytes from apoptosis. HIF-1alpha may regulate anabolic effects of chondrocytes under hypoxic conditions by regulating HSP70 (show HSP70 ELISA Kits) expression

  3. Transcatheter arterial embolization of liver tumors increases the expression of HIF-1alpha at protein level in the residual viable tumor.

  4. Upregulation of HIF-1 protects cardiac myocyte function after ischemia/reperfusion by maintaining calcium release.

  5. HIF-1alpha expression in early atherosclerosis can promote the formation of neovascularization.

  6. Xells respond to hypoxia through a transcription factor, hypoxia-inducible factor 1

  7. Upregulation of HIF-1 could protect isolated cardiac myocytes against nitrate tolerance through a cyclic GMP protein kinase-independent mechanism and through a kinase-dependent mechanism in myocardial stunning.

  8. rhEPO can down-regulate HIF-1alpha expression in the retina of rabbits with acute high intraocular pressure.

  9. Increased HIF-1 alpha protects the functional effects of cyclic GMP thorough maintenance of cyclic GMP protein kinase activity after ischemic-reperfusion

Caenorhabditis elegans (C. elegans) Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) interaction partners

  1. blocking HIF-1 activity may promote survival in cells with compromised mitochondrial function.

  2. HIF-1-mediated activation of 5-HT (show DDC ELISA Kits) signalling promotes axon regeneration by activating both the RhoA (show RHOA ELISA Kits) and cAMP pathways.

  3. this study reports that neuronal stabilization of HIF-1 mediates these effects in Caenorhabditis elegans through a cell nonautonomous signal to the intestine, which results in activation of the xenobiotic detoxification enzyme flavin-containing monooxygenase-2 (FMO-2 (show FMO2 ELISA Kits)).

  4. AMPK (show PRKAA1 ELISA Kits) and HIF-1 may control immunity and longevity tightly by acting as feedback regulators of ROS (show ROS1 ELISA Kits)

  5. Growth in hypoxia increases longevity in wild-type worms but not in animals lacking HIF-1 or DAF-16. Conversely, hypoxia shortens life span in combination with overexpression of the antioxidant stress response protein SKN-1.

  6. Increased levels of hydrogen peroxide induce a HIF-1-dependent modification of lipid metabolism in AMPK (show PRKAA1 ELISA Kits) compromised C. elegans dauer larvae.

  7. These data show that HIF-1 regulates intestinal iron homeostasis during iron deficiency by activating and inhibiting genes involved in iron uptake and storage.

  8. Data indicate that genes sqrd-1, ethe-1, cysl-1, cysl-2 and HIF-1 are involved in survival to hydrogen sulfide and hydrogen cyanide.

  9. Data show that stabilization of HIF-1 increases life span robustly under all conditions tested; however, deletion of hif-1 increases life span in a temperature-dependent manner.

  10. Data show that that reactive oxygen species (ROS (show ROS1 ELISA Kits)) are increased in respiration mutants and that mild increases in ROS (show ROS1 ELISA Kits) can stimulate HIF-1 to activate gene expression and promote longevity.

Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) Antigen Profile

Antigen Summary

This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Alternative names and synonyms associated with Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A)

  • hypoxia inducible factor 1 alpha (hif-1a) Elisa Kit
  • hypoxia inducible factor 1, alpha subunit (Hif1a) Elisa Kit
  • hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (HIF1A) Elisa Kit
  • hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (Hif1a) Elisa Kit
  • hypoxia-inducible factor 1 alpha (hif-1a) Elisa Kit
  • hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (Hif1a) Elisa Kit
  • Protein HIF-1 (hif-1) Elisa Kit
  • AA959795 Elisa Kit
  • bHLHe78 Elisa Kit
  • hif-1a Elisa Kit
  • HIF-1alpha Elisa Kit
  • HIF1 Elisa Kit
  • HIF1-alpha Elisa Kit
  • hif1a Elisa Kit
  • HIF1alpha Elisa Kit
  • MOP1 Elisa Kit
  • PASD8 Elisa Kit

Protein level used designations for HIF1A

HIF-1 alpha , HIF-1-alpha , HIF1 alpha , HIF1-alpha , Hypoxia-inducible factor 1 alpha , hypoxia-inducible factor 1-alpha , ARNT-interacting protein , ARNT interacting protein , PAS domain-containing protein 8 , basic-helix-loop-helix-PAS protein MOP1 , class E basic helix-loop-helix protein 78 , hypoxia-inducible factor 1 alpha isoform I.3 , hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) , hypoxia-inducible factor1alpha , member of PAS protein 1 , member of PAS superfamily 1 , hypoxia-inducible factor 1 alpha , hypoxia inducible factor 1 alpha subunit , hypoxia inducible factor 1, alpha subunit

GENE ID SPECIES
100337573 Xenopus laevis
15251 Mus musculus
3091 Homo sapiens
396696 Sus scrofa
281814 Bos taurus
101692645 Mustela putorius furo
443519 Ovis aries
100009579 Oryctolagus cuniculus
480348 Canis lupus familiaris
100713113 Cavia porcellus
374177 Gallus gallus
100135944 Oncorhynchus mykiss
29560 Rattus norvegicus
180359 Caenorhabditis elegans
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