You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8) ELISA Kits

Full name:
Solute Carrier Family 30 (Zinc Transporter), Member 8 ELISA Kits (SLC30A8)
On www.antibodies-online.com are 9 Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8) ELISA Kits from 6 different suppliers available. Additionally we are shipping Solute Carrier Family 30 (Zinc Transporter), Member 8 Antibodies (44) and Solute Carrier Family 30 (Zinc Transporter), Member 8 Proteins (6) and many more products for this protein. A total of 62 Solute Carrier Family 30 (Zinc Transporter), Member 8 products are currently listed.
Synonyms:
C820002P14Rik, DKFZp469F0128, HMDPC, slc30a3, wu:fe49g03, ZnT-8, ZnT-10, ZNT8, ZNT10, ZRC1
list all ELISA KIts Gene Name GeneID UniProt
SLC30A8 239436 Q8BGG0
SLC30A8 299903 P0CE46
SLC30A8 169026 Q8IWU4

Show all species

Show all synonyms

Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8) ELISA Kits by Reactivity

Select your species

More ELISA Kits for Solute Carrier Family 30 (Zinc Transporter), Member 8 Interaction Partners

Pig (Porcine) Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8) interaction partners

  1. slc30A8 colocalizes with ghrelin (show GHRL ELISA Kits) and motilin (show MLN ELISA Kits) in the gastrointestinal tract of pigs

  2. The absence of ZnT8 in glucagon (show GCG ELISA Kits)-producing cells in pig islets indicates that zinc homeostasis is mediated by a different cellular mechanism compared with human islet cells.

Mouse (Murine) Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8) interaction partners

  1. Our findings demonstrate that glucose homeostasis in the mouse improves as beta-cell ZnT8 activity increases, and remarkably, these changes track Zn(2+) rather than insulin (show INS ELISA Kits) release in vitro.

  2. Deletion of ZnT8 in a limited subset ( approximately 15%) of alpha-pancreatic cells is sufficient to increase glucagon (show GCG ELISA Kits) secretion at low glucose concentrations in vitro and in vivo and to improve the response to hypoglycemia.

  3. ischemic retinopathy maybe mediated by aberrant Zn(++) homeostasis caused by ZnT8 downregulation, whereas YC-1 (show RBMS1 ELISA Kits) plays a neuroprotective role against ischemic insult

  4. Data suggest that, despite a marked reduction in islet zinc content, the absence of ZnT-8 does not have a substantial impact on mouse physiology.

  5. Beta-cell Znt8 alone does not considerably aggravate weight gain and glucose intolerance during metabolic stress imposed by an high-fat high-calorie diet. Global loss of Znt8 is involved in diet-induced obesity and resulting insulin (show INS ELISA Kits) resistance.

  6. Downregulation of ZnT8 may be associated with impaired function of beta-cells in diabetes.

  7. Mutation of two Pdx-1 (show PDX1 ELISA Kits)-binding sites in enhancer A markedly reduces fusion gene expression suggesting that this factor contributes to Slc30a8 expression in beta-c

  8. Our data indicate that while, under the conditions studied, ZnT8 is absolutely essential for proper beta cell function, it is largely dispensable for alpha cell function.

  9. Results suggest that an acute decrease in ZnT8 levels impairs beta-cell function and Zn homeostasis, and may contribute to inflammatory cytokine-induced alterations in beta-cell function.

  10. Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands.

Human Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8) interaction partners

  1. results indicate that residues in the transmembrane and C-terminal domains together confer optimal manganese transport capability to SLC30A10 and suggest that the mechanism of ion coordination in the transmembrane domain of SLC30A10 may be substantially different from that in YiiP/other SLC30 proteins.

  2. We investigated the association of the polymorphisms rs13266634 (SLC30A8) in a case-control study in Euro-Brazilians with gestational diabetes. The minor allele frequencies, for healthy and gestational diabetes, respectively, for the T-allele (SLC30A8 gene rs13266634) were 27.8% (95%CI = 23-32%) vs 23.5% (95%CI = 18-29%), P = 0.227. Genotype comparisons showed no significant difference.

  3. Two miR (show MLXIP ELISA Kits)-binding SNPs SLC30A8 rs2466293 and INSR (show INSR ELISA Kits) rs1366600 increased Gestational diabetes mellitus susceptibility. Functional studies were required to confirm the underlying mechanism.

  4. we have successfully constructed a T1D phage display antibody library and identified two ZnT8-specific scFv clones, C27 and C22. These ZnT8-specific scFvs are potential agents in immunodiagnostic and immunotherapy of T1D

  5. allele was also associated with increased sway velocity (15%, P = .033; adjusted for age and sex) and reduced SLC30A10 expression

  6. Detection of ZnT8 antibodies in blood precedes detection of classical islet antibodies in children at risk of developing diabetes mellitus type 1.

  7. Studies indicate that people who have particular mutations in a gene called SLC30A8 (Solute carrier family 30, member 8) are 65% less likely to get diabetes.

  8. Association between SLC30A8 rs13266634 Polymorphism and Type 2 Diabetes Risk

  9. Size and the direction of the effect of SLC30A8 risk alleles in man.

  10. We describe early disease manifestations (including videos) in 5 previously unreported Indian children, carrying novel homozygous SLC30A10 mutation

Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8) Antigen Profile

Antigen Summary

This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene.

Alternative names and synonyms associated with Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8)

  • solute carrier family 30 (zinc transporter), member 8 (slc30a8) Elisa Kit
  • solute carrier family 30 (zinc transporter), member 8 (SLC30A8) Elisa Kit
  • solute carrier family 30 member 8 (LOC100347644) Elisa Kit
  • solute carrier family 39 (zinc transporter), member 8 (SLC39A8) Elisa Kit
  • solute carrier family 30 (zinc transporter), member 8 (Slc30a8) Elisa Kit
  • solute carrier family 30, member 10 (SLC30A10) Elisa Kit
  • C820002P14Rik Elisa Kit
  • DKFZp469F0128 Elisa Kit
  • HMDPC Elisa Kit
  • slc30a3 Elisa Kit
  • wu:fe49g03 Elisa Kit
  • ZnT-8 Elisa Kit
  • ZnT-10 Elisa Kit
  • ZNT8 Elisa Kit
  • ZNT10 Elisa Kit
  • ZRC1 Elisa Kit

Protein level used designations for SLC30A8

ZnT8 , solute carrier family 30 (zinc transporter), member 8 , zinc transporter 8 , znT-8 , solute carrier family 30 member 8 , solute carrier family 30 (zinc transporter), member 3 , zinc transporter 8-like , solute carrier family 39 (zinc transporter), member 8 , zinc transporter ZIP8 , zinc transporter ZnT-8 , zinc transporter 10

GENE ID SPECIES
326926 Danio rerio
420285 Gallus gallus
464348 Pan troglodytes
482022 Canis lupus familiaris
496450 Xenopus (Silurana) tropicalis
701127 Macaca mulatta
100056898 Equus caballus
100155672 Sus scrofa
100461137 Pongo abelii
100595779 Nomascus leucogenys
100347644 Oryctolagus cuniculus
430411 Gallus gallus
461405 Pan troglodytes
478494 Canis lupus familiaris
508193 Bos taurus
100171966 Pongo abelii
100385303 Callithrix jacchus
239436 Mus musculus
299903 Rattus norvegicus
169026 Homo sapiens
496294 Xenopus laevis
55532 Homo sapiens
Selected quality suppliers for Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8) ELISA Kits
Did you look for something else?