Browse our BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) ELISA Kits

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BRCA1/BRCA2-Containing Complex, Subunit 3 ELISA Kits (BRCC3)
On www.antibodies-online.com are 4 BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) ELISA Kits from 3 different suppliers available. Additionally we are shipping BRCA1/BRCA2-Containing Complex, Subunit 3 Antibodies (101) and BRCA1/BRCA2-Containing Complex, Subunit 3 Proteins (14) and many more products for this protein. A total of 126 BRCA1/BRCA2-Containing Complex, Subunit 3 products are currently listed.
Synonyms:
brcc3, brcc36, C6.1A, CXorf53, xtp1
list all ELISA KIts Gene Name GeneID UniProt
BRCC3 79184 P46736
Mouse BRCC3 BRCC3 210766 P46737
Rat BRCC3 BRCC3 316794 B2RYM5

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BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) ELISA Kits by Reactivity

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Top referenced BRCA1/BRCA2-Containing Complex, Subunit 3 ELISA Kits

  1. Human BRCC3 ELISA Kit for Sandwich ELISA - ABIN1874463 : Li, Li, Yu, Zhang, Wang, Jia: miR-3940-5p associated with genetic damage in workers exposed to hexavalent chromium. in Toxicology letters 2014 (PubMed)

More ELISA Kits for BRCA1/BRCA2-Containing Complex, Subunit 3 Interaction Partners

Human BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) interaction partners

  1. In late S/G2 (show STRN3 ELISA Kits) phase, the DNA damage-responsive E3 ligase RNF8 (show RNF8 ELISA Kits) conjugates K63-linked ubiquitin chains to tankyrase 1 (show TNKS ELISA Kits), while in G1 phase such ubiquitin chains are removed by BRISC, an ABRO1 (show FAM175B ELISA Kits)/BRCC36-containing deubiquitinase complex.

  2. findings uncover a pivotal role of BRCC36 DUB in limiting DSB processing and repair and illustrate how cells may physically couple ubiquitin recognition and metabolizing activities for fine tuning of DNA repair processes.

  3. BRCC3 may play a role in B7-H3 (show CD276 ELISA Kits)-induced 5-Fu resistance.

  4. BRCC3 inversely correlated with NPC (show NPC1 ELISA Kits) overall and relapse-free survival. Its expression was higher in radioresistant NPC (show NPC1 ELISA Kits) cells, where BRCC3 knockdown increased the cell survival fraction, attenuated DNA damage repair and resulted in G2/M cell cycle arrest.

  5. BRCC3 likely plays a role as tumor-associated gene in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms.

  6. KIAA0157 (show FAM175B ELISA Kits) allosterically activates a cognate deubiquitinating enzyme (DUB) partner and implicates super dimerization as a new regulatory mechanism underlying BRCC36 DUB activity.

  7. upregulation of BRCC3 expression is associated with glioma.

  8. these data strongly suggest that BRCC3, a deubiquitinating enzyme that is part of the cellular BRCA1 and BRISC complexes, is an important player in angiogenesis and that BRCC3 loss-of-function mutations are associated with moyamoya angiopathy.

  9. NBA1/MERIT40 (show BABAM1 ELISA Kits) and BRE (show BRE ELISA Kits) interaction is required for the integrity of two distinct deubiquitinating enzyme BRCC36-containing complexes

  10. scaffold proteins not only participate in the regulation of BRCC36 activity but also determine its subcellular localization and cellular functions.

Mouse (Murine) BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) interaction partners

  1. The deubiquitinating enzyme, BRCC3, is a critical regulator of NLRP3 (show NLRP3 ELISA Kits) activity by promoting its deubiquitination.

BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) Antigen Profile

Antigen Summary

This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5.

Alternative names and synonyms associated with BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)

  • BRCA1/BRCA2-containing complex, subunit 3 (BRCC3) Elisa Kit
  • DEP domain containing 1B (depdc1b) Elisa Kit
  • BRCA1/BRCA2-containing complex, subunit 3 (LOC100339276) Elisa Kit
  • BRCA1/BRCA2-containing complex subunit 3 (brcc3) Elisa Kit
  • BRCA1/BRCA2-containing complex, subunit 3 (Brcc3) Elisa Kit
  • BRCA1/BRCA2-containing complex, subunit 3 (BRCC36) Elisa Kit
  • BRCA1/BRCA2-containing complex, subunit 3 (brcc3) Elisa Kit
  • brcc3 Elisa Kit
  • brcc36 Elisa Kit
  • C6.1A Elisa Kit
  • CXorf53 Elisa Kit
  • xtp1 Elisa Kit

Protein level used designations for BRCC3

BRCA1/BRCA2-containing complex, subunit 3 , c6.1A , BRCA1-A complex subunit BRCC36 , BRCA1/BRCA2-containing complex subunit 3 , BRCA1/BRCA2-containing complex subunit 36 , BRISC complex subunit BRCC36 , lys-63-specific deubiquitinase BRCC36 , 6.1A protein

GENE ID SPECIES
422201 Gallus gallus
465951 Pan troglodytes
612642 Canis lupus familiaris
702888 Macaca mulatta
100158588 Xenopus (Silurana) tropicalis
100172840 Pongo abelii
100339276 Oryctolagus cuniculus
100607439 Nomascus leucogenys
100195855 Salmo salar
79184 Homo sapiens
210766 Mus musculus
316794 Rattus norvegicus
519513 Bos taurus
100516948 Sus scrofa
447688 Xenopus laevis
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