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Human Polyclonal DEFB103A Primary Antibody for ELISA, WB - ABIN2473300
Ulick, Tedde, Mantero: Pathogenesis of the type 2 variant of the syndrome of apparent mineralocorticoid excess. in The Journal of clinical endocrinology and metabolism 1990
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Human Polyclonal DEFB103A Primary Antibody for ELISA, WB - ABIN2473299
Harder, Bartels, Christophers, Schroder: Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic. in The Journal of biological chemistry 2001
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this study shows that hBD3 amplifies the response to bacterial DNA in both mouse and human immune cells in a TLR9 (show TLR9 Antibodies)-dependent manner
the role of DEFB103 gene copy number variation (CNV) in ankylosing spondylitis (AS) susceptibility, was investigated.
It may be concluded hepatitis B virus up-regulates HBD-3 and A3G expression in vivo and in vitro in placental trophoblast and lack of this up-regulation is possibly associated with intrauterine transmission of hepatitis B.
these observations suggest that there may be an interracial difference in DEFB4 (show DEFB104A Antibodies)/103A copy numbers between admixed populations and a relationship between DEFB1 (show DEFB1 Antibodies) single nucleotide polymorphisms and DEFB4 (show DEFB104A Antibodies)/103A copy number variation
Human beta-defensin 3 peptide is increased and redistributed in Crohn's ileitis
study demonstrates that HBD2 (show DEFB4 Antibodies) and 3 activate plasmacytoid dendritic cells by enhancing the intracellular uptake of CpG and self DNA and promote DNA-induced IFN-alpha (show IFNA Antibodies) production in a TLR9 (show TLR9 Antibodies)-dependent manner
Mapping of key residues in the interaction between human Beta-defensin 3 and CXCR4 (show CXCR4 Antibodies) reveals key defensin (show DEF Antibodies) motifs involved in protein binding.
These results suggest an important role for hBD3 in inducing dendritic cell activation, migration, and polarization.
Using a large, unique cohort of pediatric CA-SAB (show SH3BP5 Antibodies), this study found no significant association between DEFB1 (show DEFB1 Antibodies) genetic variation or DEFB4 (show DEFB104A Antibodies)/DEFB103 gene copy number and susceptibility for Staphylococcus aureus bacteremia
Human beta-defensin 3 exhibits further functions than antimicrobial peptide (show cAMP Antibodies) activity in cultured bone cells, including stimulation of proliferation and differentiation.
Thus, oral epithelial cells dominantly control IL-17R-dependent responses to oropharyngeal candidiasis through regulation of BD3 expression.
C/EBPbeta (show CEBPB Antibodies) contributes to immunity to mucosal candidiasis during cortisone immunosuppression in a manner linked to beta-defensin 3 expression, but is apparently dispensable for the IL-17 (show IL17A Antibodies)-dependent response.
Stress decreases mouse beta-defensin-3 expression in the esophagus of mice with diabetes.
visfatin (show NAMPT Antibodies) enhances CAMP, hBD-2 (show DEFB4 Antibodies), hBD-3, and S100A7 (show S100A7 Antibodies) production in human keratinocytes and their orthologs in murine imiquimod-treated psoriatic skin.
this investigation revealed an indispensable role for BD3, BD4 (show DEFB4 Antibodies), and CRAMP in defense against F. solani-induced keratitis
SP-A (show SFTPA1 Antibodies) protects lung epithelium from tissue injury caused by BD3
Mouse beta-defensin 3 was strongly up-regulated in colonic epithelium of 15 (but not 5) week-old IL-2 (show IL2 Antibodies)(-/-) mice and in dextran-sulfate-induced chronic (but not acute) colitis, but not in IL-2 (show IL2 Antibodies)(+/-) 15-week-old mice.
Epithelial and mucosal tissues expressed bd3 and recombinant bd3 exhibits antifungal activity.
Murine beta-defensins BD2 (show DEFB4 Antibodies) and BD3 together promote resistance against corneal infection by Pseudomonas aeruginosa.
Mycobacterial infection induces the expression of mBD3 (show MBD3 Antibodies) and mBD4 (show MBD4 Antibodies), and both might participate in the control of mycobacterial growth.
Bovine DEFB3 gene expression is upregulated by vitamin D and toll (show TLR4 Antibodies)-like receptor signaling.
The synthetic peptides bovine enteric beta-defensin (EBD (show DEFB1 Antibodies)), bovine neutrophil beta-defensin (show DEFB1 Antibodies) (BNBD) 9 and BNBD 3 are chemotactic for immature dendritic cells.
Beta-defensin (show DEFB1 Antibodies) antimicrobial peptides DEFB2 (show DEFB4 Antibodies) and DEFB3.
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103B, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.
, beta-defensin 3
, defensin, beta 103
, defensin, beta 3
, defensin-like protein
, beta defensin 3
, beta-defensin 103A
, defensin, beta 103B
, defensin, beta 103A
, beta-defensin 405
, beta-defensin 6
, bovine neutrophil beta-defensin 3