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IKZF1 Proteins

(IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
This gene encodes a transcription factor that belongs to the family of zinc-finger DNA binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. All isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homodimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and contain the nuclear localization signal, resulting in members with and without DNA-binding properties. Only few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes. The non-DNA-binding isoforms are largely found in the cytoplasm, and thought to function as dominant negative factors. Overexpression of some dominant-negative isoforms have been associated with B-cell malignancies, such as acute lymphoblastic leukemia (ALL). [provided by RefSeq, May 2011].
IKZF1 Protein (AA 1-477) (GST tag) IKZF1 Protein (AA 1-477) (GST tag) IKZF1 Protein (AA 1-477) (GST tag) (ABIN1307650)

IKZF1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

IKZF1 Protein (AA 1-519) (His tag) IKZF1 Protein (AA 1-519) (His tag) IKZF1 Protein (AA 1-519) (His tag) (ABIN7123400)

IKZF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

IKZF1 Protein (AA 1-519) (His tag) IKZF1 Protein (AA 1-519) (His tag) IKZF1 Protein (AA 1-519) (His tag) (ABIN3093023)

Crystallography grade IKZF1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

IKZF1 Proteins by Grade

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IKZF1 Proteins by Origin

Find IKZF1 Proteins for a variety of species such as anti-Human IKZF1, anti-Mouse IKZF1. The species listed below are among those available. Click on a link to go to the corresponding products.

IKZF1 Proteins by Source

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IKZF1 Proteins by Protein Type

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IKZF1 Proteins by Application

Find IKZF1 Proteins validated for a specific application such as ELISA, WB, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular IKZF1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307650
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123400
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093023
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134815
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2723364
Quantity 20 μg
Datasheet Datasheet

Aliases for IKZF1 Proteins

IKAROS family zinc finger 1 (IKZF1) Proteins
IKAROS family zinc finger 1 (Ikzf1) Proteins
IKAROS family zinc finger 1 (Ikaros) (ikzf1) Proteins
IKAROS family zinc finger 1 (ikzf1) Proteins
5832432G11Rik Proteins
hIk-1 Proteins
hik-1 Proteins
hlk-1 Proteins
Hs.54452 Proteins
hs.54452 Proteins
IK1 Proteins
ik1 Proteins
IKAROS Proteins
ikaros Proteins
Ikaros Proteins
ikzf1 Proteins
LyF-1 Proteins
LYF1 Proteins
lyf1 Proteins
MGC108252 Proteins
mKIAA4227 Proteins
PRO0758 Proteins
pro0758 Proteins
RGD1562979 Proteins
Zfpn1a1 Proteins
ZNFN1A1 Proteins
znfn1a1 Proteins
Znfn1a1 Proteins
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