Browse our anti-NLRP2 (NLRP2) Antibodies

Full name:
anti-NLR Family, Pyrin Domain Containing 2 Antibodies (NLRP2)
On www.antibodies-online.com are 173 NLR Family, Pyrin Domain Containing 2 (NLRP2) Antibodies from 22 different suppliers available. Additionally we are shipping NLRP2 Proteins (5) and NLRP2 Kits (4) and many more products for this protein. A total of 193 NLRP2 products are currently listed.
Synonyms:
CLR19.9, E330007A02Rik, Nalp2, nbs, NBS1, NLRP2, PAN1, PYPAF2
list all antibodies Gene Name GeneID UniProt
NLRP2 85482 Q9JIL9
NLRP2 55655 Q9NX02
NLRP2 232827  

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Top referenced anti-NLRP2 Antibodies

  1. Human Monoclonal NLRP2 Primary Antibody for ICC, IF - ABIN151633 : den Dulk, van Eijk, de Ruijter, Brandsma, Brouwer: The NER protein Rad33 shows functional homology to human Centrin2 and is involved in modification of Rad4. in DNA repair 2008 (PubMed)
    Show all 17 references for 151633

  2. Human Monoclonal NLRP2 Primary Antibody for ICC, IF - ABIN151641 : Suzuki, Yamauchi, Yamashita: ATM-dependent cellular response to DNA double strand breaks plays a pivotal role in the maintenance of the integrity of the genome. in Radiation protection dosimetry 2011 (PubMed)
    Show all 5 references for 151641

  3. Chicken Monoclonal NLRP2 Primary Antibody for IF, WB - ABIN968688 : Carney, Maser, Olivares, Davis, Le Beau, Yates, Hays, Morgan, Petrini: The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response. in Cell 1998 (PubMed)
    Show all 4 references for 968688

  4. Human Polyclonal NLRP2 Primary Antibody for WB - ABIN611071 : Fujita, Sato, Ishida, Tsuruo: Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for 611071

  5. Human Polyclonal NLRP2 Primary Antibody for ChIP, ICC - ABIN253125 : Dobbin, Madabhushi, Pan, Chen, Kim, Gao, Ahanonu, Pao, Qiu, Zhao, Tsai: SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons. in Nature neuroscience 2013 (PubMed)
    Show all 2 references for 253125

  6. Human Polyclonal NLRP2 Primary Antibody for IHC (p), IHC - ABIN438536 : Moeller, Yordy, Williams, Giri, Raju, Molkentine, Byers, Heymach, Story, Lee, Sturgis, Weber, Garden, Ang, Schwartz: DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy. in Clinical cancer research : an official journal of the American Association for Cancer Research 2011 (PubMed)
    Show all 2 references for 438536

  7. Mouse (Murine) Polyclonal NLRP2 Primary Antibody for IP, WB - ABIN253119 : Xie, Kwok, Scully: Role of mammalian Mre11 in classical and alternative nonhomologous end joining. in Nature structural & molecular biology 2009 (PubMed)

  8. Human Polyclonal NLRP2 Primary Antibody for EIA, WB - ABIN498067 : Ji, Shin, Kim, Oh, Min, Choi: Toll-like receptor 2 and NALP2 mediate induction of human beta-defensins by fusobacterium nucleatum in gingival epithelial cells. in Infection and immunity 2009 (PubMed)

  9. Human Polyclonal NLRP2 Primary Antibody for IHC (p), IHC - ABIN438614 : Baltanás, Casafont, Lafarga, Weruaga, Alonso, Berciano, Lafarga: Purkinje cell degeneration in pcd mice reveals large scale chromatin reorganization and gene silencing linked to defective DNA repair. in The Journal of biological chemistry 2011 (PubMed)

More Antibodies against NLRP2 Interaction Partners

Xenopus laevis NLR Family, Pyrin Domain Containing 2 (NLRP2) interaction partners

  1. Data show that TopBP1 (show TOPBP1 Antibodies) and Nbs1 associate with the N-terminal region of Mdc1 (show MDC1 Antibodies) in egg extracts.

  2. MRN (Mre11 (show MRE11A Antibodies), Rad50 (show RAD50 Antibodies), and Nbs1) complex, CtIP (show RBBP8 Antibodies), and BRCA1 are required for both the removal of Top2 (show TOP2 Antibodies)-DNA adducts and the subsequent resection of Top2 (show TOP2 Antibodies)-adducted DSB ends.

  3. MRN (MRE11 (show MRE11A Antibodies)-RAD50 (show RAD50 Antibodies)-NBS1) complex has role in ATR (show ATR Antibodies) activation via TOPBP1 (show TOPBP1 Antibodies) recruitment.

  4. Dna2 (show DNA2 Antibodies) co-localizes in foci with RPA (show RPA1 Antibodies) and is found in a complex with replication fork components And-1 and Mcm10 (show MCM10 Antibodies). Dna2 (show DNA2 Antibodies) interacts with the DSB repair and checkpoint proteins Nbs1 and ATM (show ATM Antibodies).

  5. Results indicate a role for the X. laevis Mre11 (show MRE11A Antibodies)/Rad50 (show RAD50 Antibodies)/Nbs1 complex in microhomology-mediated end joining.

  6. Through nuclear magnetic resonance three-dimensional structure determination, data demonstrate that there is a second BRCT domain (BRCT2) in Nbs1.

  7. These findings suggest that the MRN complex is a crucial mediator in the process whereby ATM (show ATM Antibodies) promotes the TopBP1 (show TOPBP1 Antibodies)-dependent activation of ATR (show ATR Antibodies)-ATRIP (show ATRIP Antibodies) in response to double-stranded DNA breaks.

  8. suggests that Mre11 (show MRE11A Antibodies)-Rad50 (show RAD50 Antibodies)-Nbs1 inactivation participates in the down-regulation of damage signaling during checkpoint recovery following double-strand breaks repair.

Human NLR Family, Pyrin Domain Containing 2 (NLRP2) interaction partners

  1. No disease-causing mutations were identified in NLRP2, NLRP7 (show NLRP7 Antibodies) and KHDC3L (show KHDC3L Antibodies) in cohorts of unexplained infertility and recurrent pregnancy loss.

  2. This study indicates that polymorphisms in SPARC and NLRP2 are related to rheumatoid arthritis susceptibility in a Chinese Han population.

  3. Findings suggest that NLR family pyrin domain containing 2 (NLRP2P) is a processed pseudogene that regulates NF-kappaB (show NFKB1 Antibodies) RelA/p65 (show NFkBP65 Antibodies) activity and thus represents the newest member of the POP (show PREP Antibodies) family, pyrin (show MEFV Antibodies)-only protein 4 (POP4 (show POP4 Antibodies); NLRP4 (show NLRP4 Antibodies)).

  4. The results of this study suggest that the astrocytic NLRP2 inflammasome is an important component of the CNS inflammatory response

  5. There is a significant association of a tag single-nucleotide polymorphism (SNP) of NLRP7 (show NLRP7 Antibodies) (rs26949) with idiopathic recurrent miscarriage

  6. single nucleotide polymorphisms in NALP2 gene is associated with arsenic induced skin lesions, peripheral neuropathy, eye problem and respiratory diseases.

  7. Observations suggest that although NLRP7 (show NLRP7 Antibodies) and C6orf221 (show KHDC3L Antibodies) mutations are related to diploid biparental FRHMs, neither of these genes, nor NLRP2, are related to diploid HMs (show CTSC Antibodies) with biparental contributions to the molar genome.

  8. POP2 (show CNOT8 Antibodies) acts as a regulator of inflammatory signals and exerts its two known functions through distinct modalities employed by its first alpha-helix

  9. Our observations are the first to implicate SPARC (show SPARC Antibodies), SLPI (show SLPI Antibodies), and NLRP2, a component of the innate immune system, in the pathogenesis of axial spondyloarthropathy

  10. functions as a modulator of the activation of NF-kappaB (show NFKB1 Antibodies) and pro-caspase-1 (show CASP1 Antibodies) in macrophages

Mouse (Murine) NLR Family, Pyrin Domain Containing 2 (NLRP2) interaction partners

  1. This work identifies Nlrp2 as a critical regulator of oocyte quality

  2. high expression of NLRP2, especially in astrocytes, may play important roles in the pathophysiological process of ischemic stroke and has potential clinical value for the treatment of ischemic stroke.

  3. Nlrp2 is a member of the mammalian maternal effect (show NLRP5 Antibodies) genes and required for early embryonic development in the mouse.

  4. POP2 (show CNOT7 Antibodies) acts as a regulator of inflammatory signals and exerts its two known functions through distinct modalities employed by its first alpha-helix

NLRP2 Antigen Profile

Antigen Summary

NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1\; MIM 147678) by Toll-like receptors (see TLR4\; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003

Alternative names and synonyms associated with NLRP2

  • NLR family, pyrin domain containing 2 (NLRP2) antibody
  • NLR family, pyrin domain containing 2 (LOC100344125) antibody
  • nibrin (nbn) antibody
  • nibrin (Nbn) antibody
  • NLR family, pyrin domain containing 2 (Nlrp2) antibody
  • CLR19.9 antibody
  • E330007A02Rik antibody
  • Nalp2 antibody
  • nbs antibody
  • NBS1 antibody
  • NLRP2 antibody
  • PAN1 antibody
  • PYPAF2 antibody

Protein level used designations for NLRP2

NLR family, pyrin domain containing 2 , NACHT, leucine rich repeat and PYD containing 2 , NACHT, LRR and PYD domains-containing protein 2-like , Nijmegen breakage syndrome 1 , nijmegen breakage syndrome protein 1 homolog , NACHT, LRR and PYD containing protein 2 , NACHT, LRR and PYD domains-containing protein 2 , PYRIN domain and NACHT domain-containing protein 1 , PYRIN-containing APAF1-like protein 2 , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2 , nucleotide-binding site protein 1

GENE ID SPECIES
484304 Canis lupus familiaris
697844 Macaca mulatta
100055187 Equus caballus
100301026 Bos taurus
100344125 Oryctolagus cuniculus
100387349 Callithrix jacchus
100516741 Sus scrofa
403373 Xenopus laevis
85482 Rattus norvegicus
55655 Homo sapiens
469011 Pan troglodytes
232827 Mus musculus
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