Browse our RNF168 (RNF168) ELISA Kits

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Ring Finger Protein 168 ELISA Kits (RNF168)
On are 0 Ring Finger Protein 168 (RNF168) ELISA Kits from different suppliers available. Additionally we are shipping RNF168 Antibodies (59) and RNF168 Proteins (6) and many more products for this protein. A total of 74 RNF168 products are currently listed.
3110001H15Rik, hRNF168
list all ELISA KIts Gene Name GeneID UniProt
Mouse RNF168 RNF168 70238 Q80XJ2
Human RNF168 RNF168 165918 Q8IYW5
Rat RNF168 RNF168 690043 B2RYR0

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More ELISA Kits for RNF168 Interaction Partners

Mouse (Murine) Ring Finger Protein 168 (RNF168) interaction partners

  1. RNF168, in complex with RAD6A (show ube2a ELISA Kits) or RAD6B (show UBE2B ELISA Kits), is activated in the DNA-damage-induced protein ubiquitination cascade.

  2. Rnf168 is important for maintaining genomic integrity, and it cooperates with p53 (show TP53 ELISA Kits) in suppressing tumorigenesis.

Human Ring Finger Protein 168 (RNF168) interaction partners

  1. Ubiquitin ligases RNF168, RNF169, and RAD18 (show RAD18 ELISA Kits) specifically bind histone H2A Lys13/15-ubiquitylated nucleosomes. 53BP1 (show TP53BP1 ELISA Kits) chromatin recruitment may be activated by RNF168 and blocked by RNF169 and RAD18 (show RAD18 ELISA Kits).

  2. deregulated RNF168/53BP1 (show TP53BP1 ELISA Kits) pathway could promote tumorigenesis by selecting for a more robust, better stress-adapted cancer cell phenotype, through altered DNA repair, fueling genomic instability and tumor heterogeneity

  3. Further mining of the UBE2U interactome uncovered its cognate E3 RNF17 (show RNF17 ELISA Kits) as a novel factor that, via the radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties (RIDDLE) syndrome protein RNF168, enforces DNA damage responses.

  4. The association of RNF168 with PML (show PML ELISA Kits) NBs (show NBN ELISA Kits) resulted in increased ubiquitylation.

  5. Results reveal an important role of USP7 (show USP7 ELISA Kits) in regulating ubiquitin-dependent signaling via stabilization of RNF168.

  6. CK2 (show CSNK2A1 ELISA Kits)/WIP1 (show PPM1D ELISA Kits)-mediated modulation of LSD1 (show KDM1A ELISA Kits) phosphorylation facilitates RNF168-dependent ubiquitination and recruitment of 53BP1 (show TP53BP1 ELISA Kits) to the DNA damage sites.

  7. The ubiquitin ligase RNF168 is strictly dependent on the activity that UbK27 is required to promote chromatin ubiquitination following DNA damage.

  8. Finding that RNF8 (show RNF8 ELISA Kits) is less abundant than RNF168 identifies RNF8 (show RNF8 ELISA Kits) as a rate-limiting determinant of focal repair complex assembly

  9. Depletion of RNF8 (show RNF8 ELISA Kits) or RNF168 blocks the degradation of diffusely localized nuclear 53BP1 (show TP53BP1 ELISA Kits).

  10. The E3 ligase RNF168 promotes both H2A ubiquitylation and neddylation. RNF168 is itself a substrate for NEDD8, and neddylation of RNF168 is necessary for its E3 ubiquitin activity.

RNF168 Antigen Profile

Antigen Summary

This gene encodes an E3 ubiquitin ligase protein that contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The protein is involved in DNA double-strand break (DSB) repair. Mutations in this gene result in Riddle syndrome.

Alternative names and synonyms associated with RNF168

  • ring finger protein 168 (Rnf168) Elisa Kit
  • ring finger protein 168, E3 ubiquitin protein ligase (rnf168) Elisa Kit
  • ring finger protein 168, E3 ubiquitin protein ligase (RNF168) Elisa Kit
  • ring finger protein 168, E3 ubiquitin protein ligase (Rnf168) Elisa Kit
  • 3110001H15Rik Elisa Kit
  • hRNF168 Elisa Kit

Protein level used designations for RNF168

E3 ubiquitin-protein ligase RNF168 , ring fnger protein 168

70238 Mus musculus
432198 Xenopus laevis
770166 Gallus gallus
165918 Homo sapiens
488029 Canis lupus familiaris
613812 Bos taurus
690043 Rattus norvegicus
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