Browse our anti-TRAF3IP2 (TRAF3IP2) Antibodies

Full name:
anti-TRAF3 Interacting Protein 2 Antibodies (TRAF3IP2)
On are 129 TRAF3 Interacting Protein 2 (TRAF3IP2) Antibodies from 22 different suppliers available. Additionally we are shipping TRAF3IP2 Proteins (3) and many more products for this protein. A total of 145 TRAF3IP2 products are currently listed.
Act1, AI429613, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, MGC134034, PSORS13, RGD1304768, t3jam, TRAF3IP2
list all antibodies Gene Name GeneID UniProt
TRAF3IP2 361857  
TRAF3IP2 10758 O43734
TRAF3IP2 103213  

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anti-Rat (Rattus) TRAF3IP2 Antibodies:

anti-Human TRAF3IP2 Antibodies:

anti-Mouse (Murine) TRAF3IP2 Antibodies:

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Top referenced anti-TRAF3IP2 Antibodies

  1. Human Polyclonal TRAF3IP2 Primary Antibody for IHC (p), SimWes - ABIN4361705 : Valente, Yoshida, Clark, Delafontaine, Siebenlist, Chandrasekar: Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK signaling. in Free radical biology & medicine 2013 (PubMed)
    Show all 6 references for 4361705

  2. Human Polyclonal TRAF3IP2 Primary Antibody for ELISA, WB - ABIN4361709 : Qian, Liu, Hartupee, Altuntas, Gulen, Jane-Wit, Xiao, Lu, Giltiay, Liu, Kordula, Zhang, Vallance, Swaidani, Aronica, Tuohy, Hamilton, Li: The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. in Nature immunology 2007 (PubMed)

  3. Human Polyclonal TRAF3IP2 Primary Antibody for WB - ABIN2472996 : Leonardi, Chariot, Claudio, Cunningham, Siebenlist: CIKS, a connection to Ikappa B kinase and stress-activated protein kinase. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)

More Antibodies against TRAF3IP2 Interaction Partners

Human TRAF3 Interacting Protein 2 (TRAF3IP2) interaction partners

  1. AP1 (show FOSB Antibodies) binding sites were enriched upstream of genes up-regulated by TRAF3IP2 silencing. Correspondingly, nuclear expression of FosB (show FOSB Antibodies) and Fra1 (show FOSL1 Antibodies) was increased in TRAF3IP2-silenced cells. Many genes involved in host defense were induced by IL-17 (show IL17A Antibodies) in a TRAF3IP2-dependent fashion.

  2. TRAF3IP2 SNP rs33980500 associated with no achievement of low disease activity nor remission at 6 months

  3. the first report to describe a non-adaptor function of Act1 by directly binding to the promoter region of IL-17A (show IL17A Antibodies) responsive genes and directly regulate their transcription.

  4. ACT1 is an essential adaptor molecule of Il-17 (show IL17A Antibodies)-induced expression of inflammation-related gene targets.

  5. Both the ACT-1 assay and the MAdCAM-1 (show MADCAM1 Antibodies) assay demonstrated acceptable reproducibility and repeatability. The assays were sufficiently stable to allow for clinical use. During clinical testing the assays demonstrated that vedolizumab was able to saturate peripheral cells at all doses tested.

  6. A G/G genotype of rs766748 in IL-17F (show IL17F Antibodies), and a C/C or C/A genotype of rs1883136 in TRAF3IP2.

  7. The suppressive effects of miR (show MLXIP Antibodies)-30a were mediated by directly targeting Traf3ip2 mRNA

  8. TRAF3IP2 may play a causal role in aldosterone-induced adverse cardiac remodeling in vivo.

  9. Single nucleotide polymorphisms in RBPJ (show RBPJ Antibodies), IL1R1 (show IL1RN Antibodies), REV3L (show REV3L Antibodies), TRAF3IP2, IRF1 (show IRF1 Antibodies) and ICOS (show CTLA4 Antibodies) showed association with rheumatoid arthritis in black South Africans.

  10. A variant (rs76228616 SNP) in TRAF3IP2 gene could be involved in susceptibility to Steven-Johnson Syndrome.

Mouse (Murine) TRAF3 Interacting Protein 2 (TRAF3IP2) interaction partners

  1. ameliorating myocardial damage by targeting TRAF3IP2 appears to be more effective to inhibiting its downstream signaling intermediates NF-kappaB (show NFKB1 Antibodies) and JNK (show MAPK8 Antibodies). Therefore, TRAF3IP2 could be a potential therapeutic target in ischemic heart disease

  2. these results demonstrate that overexpression of TRAF3IP2 in male mice is sufficient to induce myocardial hypertrophy, cardiac fibrosis, and contractile dysfunction.

  3. using massively parallel reporter assays, we dissect the enhancer activity of three liver eExons (SORL1 (show SORL1 Antibodies) exon 17, TRAF3IP2 exon 2, PPARG (show PPARG Antibodies) exon 6) at single nucleotide resolution in the mouse liver

  4. TRAF3IP2 is a critical intermediate in IL-18 (show IL18 Antibodies)-induced cardiac fibroblast migration and differentiation in vitro.

  5. Our results support the important role of Act1 in the regulation of self-reactive B cells and reveal how Act1 functions to prevent the production of autoantibodies.

  6. These results demonstrate for the first time that AOPPs induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent

  7. CIKS knockdown inhibited high glucose-induced IKKbeta (show IKBKB Antibodies) and JNK (show MAPK8 Antibodies) phosphorylation, p65 (show NFkBP65 Antibodies) and c-Jun (show JUN Antibodies) nuclear translocation, and NF-kappaB (show NFKB1 Antibodies)- and AP-1 (show JUN Antibodies)-dependent proinflammatory cytokine, chemokine (show CCL1 Antibodies), and adhesion molecule (show NCAM1 Antibodies) expression.

  8. The findings define a new role for the IKK-related kinases in suppressing IL-17-mediated NF-kappaB activation through TRAF6-dependent Act1 phosphorylation.

  9. Data show that deletion of the CC' loop from Act1 or IL-17RA (show IL17RA Antibodies) abolished the interaction between both proteins.

  10. our findings indicate that Act1 expression in T cells is required for cellular and humoral Th2-mediated allergic responses and the development of airway hyperresponsiveness

TRAF3IP2 Antigen Profile

Antigen Summary

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Alternative names and synonyms associated with TRAF3IP2

  • Traf3 interacting protein 2 (Traf3ip2) antibody
  • TRAF3 interacting protein 2 (TRAF3IP2) antibody
  • adapter protein CIKS-like (LOC100467029) antibody
  • adapter protein CIKS-like (LOC100480036) antibody
  • adapter protein CIKS-like (LOC100490063) antibody
  • TRAF3 interacting protein 2 (traf3ip3) antibody
  • TRAF3 interacting protein 2 (LOC100226375) antibody
  • TRAF3 interacting protein 2 (Traf3ip2) antibody
  • Act1 antibody
  • AI429613 antibody
  • C6orf2 antibody
  • C6orf4 antibody
  • C6orf5 antibody
  • C6orf6 antibody
  • CIKS antibody
  • MGC134034 antibody
  • PSORS13 antibody
  • RGD1304768 antibody
  • t3jam antibody
  • TRAF3IP2 antibody

Protein level used designations for TRAF3IP2

adapter protein CIKS , TRAF3 interacting protein 2 , adapter protein CIKS-like , NFkB-activating protein ACT1 , connection to IKK and SAPK/JNK , nuclear factor NF-kappa-B activator 1

361857 Rattus norvegicus
100390719 Callithrix jacchus
100439347 Pongo abelii
100467029 Ailuropoda melanoleuca
100473939 Ailuropoda melanoleuca
100480036 Ailuropoda melanoleuca
100490063 Xenopus (Silurana) tropicalis
421752 Gallus gallus
494853 Xenopus laevis
549319 Xenopus (Silurana) tropicalis
616801 Bos taurus
697530 Macaca mulatta
741209 Pan troglodytes
100226375 Taeniopygia guttata
10758 Homo sapiens
103213 Mus musculus
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