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Importin 4 Proteins

(Importin 4 (IPO4))

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

recommended

Importin 4 Protein (IPO4) (AA 136-289) (His tag) (ABIN7123414)

IPO4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

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recommended

Importin 4 Protein (IPO4) (AA 1-1081) (His tag) (ABIN3093101)

Crystallography grade IPO4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

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recommended

Importin 4 Protein (IPO4) (AA 1-1082) (His tag) (ABIN3136761)

Crystallography grade IPO4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

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Importin 4 Proteins by Grade

Find Importin 4 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Importin 4 Proteins by Origin

Find Importin 4 Proteins for a variety of species such as anti-Human Importin 4, anti-Mouse Importin 4. The species listed below are among those available. Click on a link to go to the corresponding products.

Importin 4 Proteins by Source

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Importin 4 Proteins by Protein Type

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Importin 4 Proteins by Application

Find Importin 4 Proteins validated for a specific application such as WB, ELISA, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Importin 4 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Importin 4 Protein (IPO4) (AA 136-289) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123414

Quantity 50 μg

Datasheet Datasheet

Importin 4 Protein (IPO4) (AA 1-1081) (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3093101

Quantity 1 mg

Datasheet Datasheet

Importin 4 Protein (IPO4) (AA 1-1082) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3136761

Quantity 1 mg

Datasheet Datasheet

Importin 4 Protein (IPO4) (AA 1-189) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7421347

Quantity 100 μg

Datasheet Datasheet

Importin 4 Protein (IPO4) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2730458

Quantity 20 μg

Datasheet Datasheet

Aliases for Importin 4 Proteins

importin 4 (IPO4) Proteins
importin 4 (Ipo4) Proteins
8430408O15Rik Proteins
AA409693 Proteins
Imp4 Proteins
Imp4a Proteins
RanBP4 Proteins

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Importin 4 Proteins by Grade

Importin 4 Proteins by Origin

Importin 4 Proteins by Source

Importin 4 Proteins by Protein Type

Importin 4 Proteins by Application

Popular Importin 4 Proteins

Aliases for Importin 4 Proteins

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