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anti-Human TXNIP Antibodies:
anti-Mouse (Murine) TXNIP Antibodies:
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Mouse (Murine) Polyclonal TXNIP Primary Antibody for WB - ABIN1881961
Martin: [Growing old]. in Revue médicale suisse 2010
Show all 5 Pubmed References
Human Polyclonal TXNIP Primary Antibody for WB - ABIN1881962
Zhuo, Niu, Chen, Xin, Guo, Mao: Vitamin D3 up-regulated protein 1(VDUP1) is regulated by FOXO3A and miR-17-5p at the transcriptional and post-transcriptional levels, respectively, in senescent fibroblasts. in The Journal of biological chemistry 2010
Show all 4 Pubmed References
Human Monoclonal TXNIP Primary Antibody for IHC (p), IP - ABIN5080370
Zaragoza-Campillo, Morán: Reactive Oxygen Species Evoked by Potassium Deprivation and Staurosporine Inactivate Akt and Induce the Expression of TXNIP in Cerebellar Granule Neurons. in Oxidative medicine and cellular longevity 2017
Show all 2 Pubmed References
Human Polyclonal TXNIP Primary Antibody for WB - ABIN4250210
Lee, Lee, Bae, Kang, Kim: Genome-wide identification of target genes for miR-204 and miR-211 identifies their proliferation stimulatory role in breast cancer cells. in Scientific reports 2016
Human Polyclonal TXNIP Primary Antibody for IF (p), IHC (p) - ABIN750808
Li, Shen, Sun, Li, Sun, Liu, Zhang, Huang, Meng, Li: MicroRNA-20a negatively regulates expression of NLRP3-inflammasome by targeting TXNIP in adjuvant-induced arthritis fibroblast-like synoviocytes. in Joint, bone, spine : revue du rhumatisme 2016
Cow (Bovine) Polyclonal TXNIP Primary Antibody for WB - ABIN2784817
Stoltzman, Peterson, Breen, Muoio, Billin, Ayer: Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. in Proceedings of the National Academy of Sciences of the United States of America 2008
the association of TXNIP (thioredoxin-interacting protein) with NLRP3 (show NLRP3 Antibodies) induced by ROS (show ROS1 Antibodies) promoted NLRP3 (show NLRP3 Antibodies) inflammasome activation in senescent HUVEC endothelial cells
histone acetylation serves as a key regulator of glucose-induced increase in TXNIP gene expression
thioredoxin-interacting protein deficiency alleviates diabetic renal lipid accumulation through regulation of Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) pathway
High expression of TXNIP indicates a lower pathological grade of meningnioma, and is also associated with longer recurrence-free time.
All-trans retinoic acid plays a key role in inhibition of hepatic stellate cell activation via suppressing TXNIP expression, which reduces oxidative stress levels.
Study shows that TXNIP expression is down-regulated in new Multiple Sclerosis (MS) patients compared to controls and might be implicated in pathogenesis of the disease.
TXNIP Single nucleotide polymorphisms may individually and cumulatively affect CAD (show CAD Antibodies) risk through a possible mechanism for regulating TXNIP expression and gene-environment interactions.
Taken together, our results firstly reveal that TMAO induces inflammation and endothelial dysfunction via activating ROS (show ROS1 Antibodies)-TXNIP-NLRP3 (show NLRP3 Antibodies) inflammasome, suggest a likely mechanism for TMAO-dependent enhancement in atherosclerosis and cardiovascular risks.
results suggest that TXNIP is required early in the apoptotic-inducing pathway resulting from r-Moj-DM binding to the alphav integrin (show ITGAV Antibodies) subunit
Hypoxia suppresses thioredoxin binding protein-2 gene expression, which may ultimately alter placental development.
The molecular characterization of porcine TXNIP gene, is described.
single-marker and haplotype analyses revealed significant effects of TXNIP on hot carcass weight, test daily gain, and lifetime daily gain
Foam cell-released 4-hydroxnonenal activates PPARdelta (show PPARD Antibodies) in Vascular endothelial cells, leading to increased TXNIP expression and consequently to senescence.
TXNIP-NFYA (show NFYA Antibodies)-SREBP2 (show SREBF2 Antibodies)/miR (show MLXIP Antibodies)-33a-AMPKalpha (show GRK4 Antibodies)/CROT (show CROT Antibodies)/CPT1 (show CPT1A Antibodies)/HADHB (show HADHB Antibodies) pathway is conserved in mouse, rat, and human cardiomyocytes and regulates myocardial beta-oxidation.
results suggest that melatonin confers protection against Cd-induced liver inflammation and hepatocyte death via inhibition of the TXNIP-NLRP3 (show NLRP3 Antibodies) inflammasome pathway.
proteomic and functional analyses demonstrated that Txnip inhibits glucose transport through direct binding to glucose transporter 1 (GLUT1 (show SLC2A1 Antibodies)). An ex vivo analysis of perfused hearts further demonstrated that the enhanced functional reserve afforded by deletion of Txnip was associated with myocardial glucose utilization during beta-adrenergic stimulation.
Thrombin (show F2 Antibodies) activates reactive oxygen species (ROS (show ROS1 Antibodies))/thioredoxin (show TXN Antibodies) binding protein (TXNIP)/NLRP3 (show NLRP3 Antibodies) signaling in BV2 (show DNAH9 Antibodies) microglia cells, which may indicate a mechanism that pro-inflammatory and pro-apoptotic contributes to the development of intracerebral hemorrhage (ICH (show ACE Antibodies)).
TxNIP appears to be an important factor in FFA-induced ROS (show ROS1 Antibodies) generation and insulin (show INS Antibodies) resistance in skeletal muscle cells
Glucose exerts strong stimulatory effects on activation histone marks while having inhibitory effects on repression marks in the promoter of the TXNIP gene, and this was associated with a marked increase in expression of the proinflammatory gene in kidney.
Diabetes induces TXNIP expressions at mRNA levels, but shows the opposite effect on GS.
ITCH targets TXNIP for ubiquitin-proteasome degradation in cardiomyocytes and ameliorates reactive oxygen species-induced cardiotoxicity through the thioredoxin (show TXN Antibodies) system.
regulates thioredoxin to play an important role in the preservation of cellular viability
thioredoxin interacting protein
, Thioredoxin-interacting protein
, thioredoxin binding protein 2
, thioredoxin-binding protein 2
, thioredoxin-interacting protein
, upregulated by 1,25-dihydroxyvitamin D-3
, vitamin D3 up-regulated protein 1
, hyperlipidemia 1
, thioredoxin binding protein-2