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TNFSF9 Protein (AA 52-254, partial) (His tag)

TNFSF9 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA
Catalog No. ABIN1046589
  • Target See all TNFSF9 Proteins
    TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 52-254, partial
    Origin
    • 23
    • 10
    • 2
    • 1
    Human
    Source
    • 19
    • 10
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This TNFSF9 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS), ELISA
    Sequence
    PWAVSGARAS PGSAASPRLR EGPELSPDDP AGLLDLRQGM FAQLVAQNVL LIDGPLSWYS DPGLAGVSLT GGLSYKEDTK ELVVAKAGVY YVFFQLELRR VVAGEGSGSV SLALHLQPLR SAAGAAALAL TVDLPPASSE ARNSAFGFQG RLLHLSAGQR LGVHLHTEAR ARHAWQLTQG ATVLGLFRVT PEIPAGLPSP RSE
    Characteristics
    Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
    Purity
    90 %
    Top Product
    Discover our top product TNFSF9 Protein
  • Comment

    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    20mM Tris-Hcl, 0.5M NaCl, 10% glycerin, PH 8.0, 200 mM Imidazole
    Storage
    -20 °C
  • Won, Cha, Byun, Kim, Shin, Ahn, Kim, Rice, Walz, Kwon, Cho: "The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily." in: The Journal of biological chemistry, Vol. 285, Issue 12, pp. 9202-10, (2010) (PubMed).

    Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

    Alderson, Smith, Tough, Davis-Smith, Armitage, Falk, Roux, Baker, Sutherland, Din: "Molecular and biological characterization of human 4-1BB and its ligand." in: European journal of immunology, Vol. 24, Issue 9, pp. 2219-27, (1994) (PubMed).

  • Target
    TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
    Abstract
    TNFSF9 Products
    Synonyms
    TNFSF9 Protein, 4-1BB-L Protein, 4-1BBL Protein, AI848817 Protein, Cd137l Protein, Ly63l Protein, CD137L Protein, TNF superfamily member 9 Protein, tumor necrosis factor (ligand) superfamily, member 9 Protein, Tnfsf9 Protein, LOC476729 Protein, TNFSF9 Protein
    Background
    Synonyms: 4-1BB ligand,4-1BBL
    Molecular Weight
    25.4 kD
    UniProt
    Q07011
    Pathways
    Activated T Cell Proliferation, Cancer Immune Checkpoints
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