BDNF Protein (AA 137-237, partial) (GST tag)
(2 references)-
- Target See all BDNF Proteins
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 137-237, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BDNF protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS), ELISA
- Sequence
- ELSVCDSISE WVTAADKKTA VDMSGGTVTV LEKVPVSKGQ LKQYFYETKC NPMGYTKEGC RGIDKRHWNS QCRTTQSYVR ALTMDSKKRI GWRFIRIDTS C
- Characteristics
- During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
- Purity
- 90 %
- Top Product
- Discover our top product BDNF Protein
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Brain-Derived Neurotrophic Factor (BDNF) (AA 1-255) protein (GST tag)
BDNF Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Brain-Derived Neurotrophic Factor (BDNF) (AA 129-247) protein (His-IF2DI Tag)BDNF Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Brain-Derived Neurotrophic Factor (BDNF) (AA 1-247) protein (GST tag)BDNF Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Brain-Derived Neurotrophic Factor (BDNF) (AA 129-247) protein (His tag)Crystallography grade BDNF Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Brain-Derived Neurotrophic Factor (BDNF) (AA 131-249) protein (His tag)Crystallography grade BDNF Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Comment
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Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS buffer, 20mM GSH
- Storage
- -20 °C
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: "Characterization of the 5'-flanking region of the human brain-derived neurotrophic factor gene." in: Biochemical and biophysical research communications, Vol. 182, Issue 1, pp. 325-32, (1992) (PubMed).
: "Molecular cloning of a human gene that is a member of the nerve growth factor family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 20, pp. 8060-4, (1990) (PubMed).
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: "Characterization of the 5'-flanking region of the human brain-derived neurotrophic factor gene." in: Biochemical and biophysical research communications, Vol. 182, Issue 1, pp. 325-32, (1992) (PubMed).
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- Target
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- Alternative Name
- Brain-derived neurotrophic factor (BDNF Products)
- Background
- Synonyms: BDNF,Abrineurin
- Molecular Weight
- 38.9 kD
- UniProt
- P23560
- Pathways
- RTK Signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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