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Cathepsin B (CTSB) (AA 82-333), (partial) protein (GST tag)

Details for Product No. ABIN1046771
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Protein Name
Synonyms
apps, cpsb, LOC692390, Catb-2744, ACYPI000009, catb-1674a, Catb-84, ACYPI000014, Catb-3098, ACYPI000017, Catb-16d2, catb-16D, ACYPI000018, Catb-1874, ACYPI000019, Catb-3483, ACYPI000020, Catb-10270, A ... show more
apps, cpsb, LOC692390, Catb-2744, ACYPI000009, catb-1674a, Catb-84, ACYPI000014, Catb-3098, ACYPI000017, Catb-16d2, catb-16D, ACYPI000018, Catb-1874, ACYPI000019, Catb-3483, ACYPI000020, Catb-10270, ACYPI000021, CTSB, APPS, CPSB, CB show less
Protein Characteristics
AA 82-333, partial
Origin
Human
(21), (2), (2), (1), (1), (1)
Source
Escherichia coli (E. coli)
(8), (6), (5), (4), (4)
Protein Type Recombinant
Purification tag / Conjugate
GST tag
Application
SDS-PAGE (SDS), ELISA
Pubmed 2 references available
Quantity 200 µg
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Catalog No. ABIN1046771
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Sequence ASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRI CIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNF WTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGE GDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMA EIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIR ILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGI ESEVVAGIPRTD
Characteristics Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Purity 90 %
Alternative Name Cathepsin B
Background Synonyms: APP secretase,APPS,Cathepsin B1
Molecular Weight 55 kD
UniProt P07858
Research Area Signaling, Extracellular Matrix, Proteases
Comment

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions For Research Use only
Buffer PBS buffer, 20mM GSH
Storage -20 °C
Product cited in: Chan, San Segundo, McCormick et al.: "Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 20, pp. 7721-5, 1986 (PubMed).

Cao, Taggart, Berquin et al.: "Human gastric adenocarcinoma cathepsin B: isolation and sequencing of full-length cDNAs and polymorphisms of the gene." in: Gene, Vol. 139, Issue 2, pp. 163-9, 1994 (PubMed).

Validation Images
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