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COMM Domain Containing 4 (COMMD4) (AA 1-195), (partial) protein (GST tag)

Details for Product No. ABIN1046851, Supplier: Login to see
Protein Name
Protein Characteristics
AA 1-195, partial
Origin
Human
5
2
1
Source
Escherichia coli (E. coli)
4
2
1
1
Protein Type
Recombinant
Purification tag / Conjugate
GST tag
Application
ELISA
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Sequence MRFRFCGDLD CPDWVLAEIS TLAKMSSVKL RLLCSQVLKE LLGQGIDYEK ILKLTADAKF ESGDVKATVA VLSFILSSAA KHSVDGESLS SELQQLGLPK EHAASLCRCY EEKQSPLQKH LRVCSLRMNR LAGVGWRVDY TLSSSLLQSV EEPMVHLRLE VAAAPGTPAQ PVAMSLSADK FQVLLAELKQ AQTLM
Characteristics Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
Purity 90 %
Background Down-regulates activation of NF-kappa-B. Ref.1
Molecular Weight 48.8 kD
UniProt Q9H0A8
Pathways
Comment

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions For Research Use only
Format Lyophilized
Concentration 0.2-2 mg/mL
Buffer Tris-based buffer, 50 % glycerol
Handling Advice Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
Storage -20 °C
Storage Comment Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
Supplier Images
SDS-PAGE (SDS) image for COMM Domain Containing 4 (COMMD4) (AA 1-195), (partial) protein (GST tag) (ABIN1046851) COMM Domain Containing 4 (COMMD4) (AA 1-195), (partial) protein (GST tag)
Background publications Burstein, Hoberg, Wilkinson et al.: "COMMD proteins, a novel family of structural and functional homologs of MURR1." in: The Journal of biological chemistry, Vol. 280, Issue 23, pp. 22222-32, 2005 (PubMed).

Wiemann, Weil, Wellenreuther et al.: "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. ..." in: Genome research, Vol. 11, Issue 3, pp. 422-35, 2001 (PubMed).