Cyclin-Dependent Kinase 11A Protein A (AA 5-216), (partial) protein (GST tag)

Details for Product No. ABIN1046882
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Protein Name
Protein Characteristics
AA 5-216, partial
Escherichia coli (E. coli)
Protein Type Recombinant
Purification tag / Conjugate
GST tag
Pubmed 4 references available
Catalog no. ABIN1046882
Quantity 1 mg
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Characteristics Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.
Purity 90%
Background Synonyms: Cell division cycle 2-like protein kinase 2,Cell division protein kinase 11A,Galactosyltransferase-associated protein kinase p58/GTA,PITSLRE serine/threonine-protein kinase CDC2L2
Molecular Weight 54.1 kD
UniProt Q9UQ88

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions For Research Use only
Buffer PBS buffer, 20mM GSH
Storage -20 °C
Product cited in: Xiang, Lahti, Grenet et al.: "Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms." in: The Journal of biological chemistry, Vol. 269, Issue 22, pp. 15786-94, 1994 (PubMed).

Gururajan, Lahti, Grenet et al.: "Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2." in: Genome research, Vol. 8, Issue 9, pp. 929-39, 1998 (PubMed).

Hu, Mayeda, Trembley et al.: "CDK11 complexes promote pre-mRNA splicing." in: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 8623-9, 2003 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Hosts (3)
Reactivities (3)
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