Enolase 2 (Gamma, Neuronal) (ENO2) (AA 2-431), (partial) protein (GST tag)

Details for Product No. ABIN1047052
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Protein Name
Synonyms ENO2, DKFZp459B1817, eno3, wu:fc09h05, zgc:92418, NSE, AI837106, D6Ertd375e, Eno-2, RNEN3, Lrpb7
Protein Characteristics
AA 2-431, partial
Origin
Human
(39), (8), (3), (1), (1), (1), (1), (1), (1), (1)
Source
Escherichia coli (E. coli)
(28), (10), (9), (6), (1)
Protein Type Recombinant
Purification tag / Conjugate
GST tag
Application
SDS-PAGE (SDS), ELISA
Pubmed 3 references available
Quantity 50 µg
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Catalog No. ABIN1047052
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Sequence SIEKIWAREI LDSRGNPTVE VDLYTAKGLF RAAVPSGAST GIYEALELRD GDKQRYLGKG VLKAVDHINS TIAPALISSG LSVVEQEKLD NLMLELDGTE NKSKFGANAI LGVSLAVCKA GAAERELPLY RHIAQLAGNS DLILPVPAFN VINGGSHAGN KLAMQEFMIL PVGAESFRDA MRLGAEVYHT LKGVIKDKYG KDATNVGDEG GFAPNILENS EALELVKEAI DKAGYTEKIV IGMDVAASEF YRDGKYDLDF KSPTDPSRYI TGDQLGALYQ DFVRDYPVVS IEDPFDQDDW AAWSKFTANV GIQIVGDDLT VTNPKRIERA VEEKACNCLL LKVNQIGSVT EAIQACKLAQ ENGWGVMVSH RSGETEDTFI ADLVVGLCTG QIKTGAPCRS ERLAKYNQLM RIEEELGDEA RFAGHNFRNP
Characteristics Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival
Purity 90 %
Alternative Name Gamma-enolase
Background Synonyms: 2-phospho-D-glycerate hydro-lyase,Enolase 2,Neural enolase,Neuron-specific enolase,NSE
Molecular Weight 74.2 kD
UniProt P09104
Comment

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions For Research Use only
Buffer PBS buffer, 20mM GSH
Storage -20 °C
Product cited in: McAleese, Dunbar, Fothergill et al.: "Complete amino acid sequence of the neurone-specific gamma isozyme of enolase (NSE) from human brain and comparison with the non-neuronal alpha form (NNE)." in: European journal of biochemistry / FEBS, Vol. 178, Issue 2, pp. 413-7, 1989 (PubMed).

Van Obberghen, Kamholz, Bishop et al.: "Human gamma enolase: isolation of a cDNA clone and expression in normal and tumor tissues of human origin." in: Journal of neuroscience research, Vol. 19, Issue 4, pp. 450-6, 1988 (PubMed).

Ansari-Lari, Shen, Muzny et al.: "Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination." in: Genome research, Vol. 7, Issue 3, pp. 268-80, 1997 (PubMed).

Validation Images
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