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Enolase 2 (Gamma, Neuronal) (ENO2) (AA 2-431), (partial) protein (GST tag)

Details for Product No. ABIN1047053
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Protein Name
Protein Characteristics
AA 2-431, partial
Origin
Human
(41), (5), (3), (1), (1), (1), (1), (1), (1), (1)
Source
Escherichia coli (E. coli)
(27), (10), (9), (6), (1)
Protein Type Recombinant
Purification tag / Conjugate
GST tag
Application
SDS-PAGE (SDS), ELISA
Pubmed 3 references available
Quantity 10 µg
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Catalog No. ABIN1047053
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Sequence SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGAST GIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSG LSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGN KLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYG KDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQ DFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLT VTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ ENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRS ERLAKYNQLMRIEEELGDEARFAGHNFRNP
Characteristics Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival
Purity 90 %
Alternative Name Gamma-enolase
Background Synonyms: 2-phospho-D-glycerate hydro-lyase,Enolase 2,Neural enolase,Neuron-specific enolase,NSE
Molecular Weight 74.2 kD
UniProt P09104
Comment

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions For Research Use only
Buffer PBS buffer, 20mM GSH
Storage -20 °C
Product cited in: McAleese, Dunbar, Fothergill et al.: "Complete amino acid sequence of the neurone-specific gamma isozyme of enolase (NSE) from human brain and comparison with the non-neuronal alpha form (NNE)." in: European journal of biochemistry / FEBS, Vol. 178, Issue 2, pp. 413-7, 1989 (PubMed).

Van Obberghen, Kamholz, Bishop et al.: "Human gamma enolase: isolation of a cDNA clone and expression in normal and tumor tissues of human origin." in: Journal of neuroscience research, Vol. 19, Issue 4, pp. 450-6, 1988 (PubMed).

Ansari-Lari, Shen, Muzny et al.: "Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination." in: Genome research, Vol. 7, Issue 3, pp. 268-80, 1997 (PubMed).

Validation Images
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