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IGF2 Protein (AA 30-180, partial) (GST tag)

IGF2 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA
Catalog No. ABIN1047204
  • Target See all IGF2 Proteins
    IGF2 (Insulin-Like Growth Factor 2 (IGF2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 30-180, partial
    Origin
    • 16
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 27
    • 8
    • 3
    • 3
    • 3
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IGF2 protein is labelled with GST tag.
    Application
    SDS-PAGE (SDS), ELISA
    Sequence
    ETLCGGELVD TLQFVCGDRG FYFSRPASRV SRRSRGIVEE CCFRSCDLAL LETYCATPAK SERDVSTPPT VLPDNFPRYP VGKFFQYDTW KQSTQRLRRG LPALLRARRG HVLAKELEAF REAKRHRPLI ALPTQDPAHG GAPPEMASNR K
    Characteristics
    The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Ref.27 Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
    Purity
    90 %
    Top Product
    Discover our top product IGF2 Protein
  • Comment

    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS buffer, 20mM GSH
    Storage
    -20 °C
  • Shen, Daimon, Wang, Jansen, Ilan: "Isolation of an insulin-like growth factor II cDNA with a unique 5' untranslated region from human placenta." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 6, pp. 1947-51, (1988) (PubMed).

    Irminger, Rosen, Humbel, Villa-Komaroff: "Tissue-specific expression of insulin-like growth factor II mRNAs with distinct 5' untranslated regions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 18, pp. 6330-4, (1987) (PubMed).

    de Pagter-Holthuizen, van Schaik, Verduijn, van Ommen, Bouma, Jansen, Sussenbach: "Organization of the human genes for insulin-like growth factors I and II." in: FEBS letters, Vol. 195, Issue 1-2, pp. 179-84, (1986) (PubMed).

    Dull, Gray, Hayflick, Ullrich: "Insulin-like growth factor II precursor gene organization in relation to insulin gene family." in: Nature, Vol. 310, Issue 5980, pp. 777-81, (1984) (PubMed).

    Bell, Merryweather, Sanchez-Pescador, Stempien, Priestley, Scott, Rall: "Sequence of a cDNA clone encoding human preproinsulin-like growth factor II." in: Nature, Vol. 310, Issue 5980, pp. 775-7, (1984) (PubMed).

  • Target
    IGF2 (Insulin-Like Growth Factor 2 (IGF2))
    Alternative Name
    Insulin-Like Growth Factor II (IGF2 Products)
    Synonyms
    C11orf43 Protein, IGF-II Protein, PP9974 Protein, LOC100136550 Protein, igf2 Protein, igf2b Protein, wu:fc26e03 Protein, zgc:91781 Protein, igf-2 Protein, insigf Protein, pp9974 Protein, AL033362 Protein, Igf-2 Protein, Igf-II Protein, M6pr Protein, Mpr Protein, Peg2 Protein, IGFII Protein, RNIGF2 Protein, IGF-II-B Protein, igf2-a Protein, igf2-b Protein, insulin like growth factor 2 Protein, insulin-like growth factor II Protein, insulin-like growth factor 2a Protein, insulin like growth factor 2 S homeolog Protein, insulin-like growth factor 2 Protein, insulin-like growth factor 2 (somatomedin A) Protein, insulin like growth factor 2 L homeolog Protein, IGF2 Protein, LOC100136550 Protein, igf2a Protein, igf2.S Protein, Igf2 Protein, igf2.L Protein
    Background
    Synonyms: IGF-II,Somatomedin-A
    Molecular Weight
    44.5 kD
    UniProt
    P01344
    Pathways
    Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation
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