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Interleukin 1 alpha (IL1A) protein (His tag)

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Protein Name
Origin
Human
(66), (31), (14), (9), (4), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Source
Escherichia coli (E. coli)
(110), (15), (2), (2), (2), (1), (1)
Protein Type Recombinant
Purification tag / Conjugate
This IL1A protein is labelled with His tag.
Application
ELISA, SDS-PAGE (SDS)
Pubmed 5 references available
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Quantity 1 mg
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Characteristics Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Purity 90 %
Background Synonyms: Hematopoietin-1
Molecular Weight 24 kDa
Pathways NF-kappaB Signaling, TCR Signaling
Comment

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions For Research Use only
Format Lyophilized
Buffer PBS buffer
Storage -20 °C
Product cited in: Furutani, Notake, Fukui et al.: "Complete nucleotide sequence of the gene for human interleukin 1 alpha." in: Nucleic acids research, Vol. 14, Issue 8, pp. 3167-79, 1986 (PubMed).

Gubler, Chua, Stern et al.: "Recombinant human interleukin 1 alpha: purification and biological characterization." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 136, Issue 7, pp. 2492-7, 1986 (PubMed).

Furutani, Notake, Yamayoshi et al.: "Cloning and characterization of the cDNAs for human and rabbit interleukin-1 precursor." in: Nucleic acids research, Vol. 13, Issue 16, pp. 5869-82, 1985 (PubMed).

March, Mosley, Larsen et al.: "Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs." in: Nature, Vol. 315, Issue 6021, pp. 641-7, 1985 (PubMed).

Kotenko, Bulenkov, Veĭko et al.: "[Cloning of the cDNA coding for human prointerleukin-1 alpha and prointerleukin-1 beta]." in: Doklady Akademii nauk SSSR, Vol. 309, Issue 4, pp. 1005-8, 1990 (PubMed).

Catalog No. ABIN1047222

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