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LIM and SH3 Protein 1 (LASP1) (AA 1-243), (partial) protein (GST tag)

Details for Product No. ABIN1047340, Supplier: Log in to see
Protein Name
  • lasp1
  • MGC53336
  • LASP1
  • MGC89667
  • Lasp-1
  • MLN50
  • AA408629
  • Def-4
  • SH3P6
  • Tg(Col1a1-lacZ)1Ngma
  • fb92f05
  • wu:fb92f05
  • zgc:77542
  • lasp-1
  • mln50
  • LIM and SH3 domain protein 1
  • LIM and SH3 protein 1
  • lasp1 protein
  • lasp1
  • LASP1
  • Lasp1
Protein Characteristics
AA 1-243, partial
5
4
4
3
1
1
Origin
Human
11
1
1
1
1
1
Source
Escherichia coli (E. coli)
8
4
2
1
1
Protein Type
Recombinant
Purification tag / Conjugate
This LASP1 protein is labelled with GST tag.
Application
SDS-PAGE (SDS), ELISA
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Sequence MNPNCARCGK IVYPTEKVNC LDKFWHKACF HCETCKMTLN MKNYKGYEKK PYCNAHYPKQ SFTMVADTPE NLRLKQQSEL QSQVRYKEEF EKNKGKGFSV VADTPELQRI KKTQDQISNI KYHEEFEKSR MGPSGGEGME PERRDSQDGS SYRRPLEQQQ PHHIPTSAPV YQQPQQQPVA QSYGGYKEPA APVSIQRSAP GGGGKRYRAV YDYSAADEDE VSFQDGDTIV NVQQIDDGWM YGT
Characteristics Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types By similarity.
Purity 90 %
Background Synonyms: Metastatic lymph node gene 50 protein,MLN 50
Molecular Weight 55.2 kD
UniProt Q14847
Comment

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions For Research Use only
Format Lyophilized
Buffer PBS buffer, 20mM GSH
Storage -20 °C
Background publications Tao, Wollscheid, OBrien, Eng, Li, Bodenmiller, Watts, Hood, Aebersold: "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." in: Nature methods, Vol. 2, Issue 8, pp. 591-8, 2005 (PubMed).

Gevaert, Goethals, Martens, Van Damme, Staes, Thomas, Vandekerckhove: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." in: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, 2003 (PubMed).

Product cited in: Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Tomasetto, Régnier, Moog-Lutz, Mattei, Chenard, Lidereau, Basset, Rio: "Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17." in: Genomics, Vol. 28, Issue 3, pp. 367-76, 1996 (PubMed).

Tomasetto, Moog-Lutz, Régnier, Schreiber, Basset, Rio: "Lasp-1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domains." in: FEBS letters, Vol. 373, Issue 3, pp. 245-9, 1995 (PubMed).