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TFPI Protein (AA 29-280, partial) (GST tag)

TFPI Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
Catalog No. ABIN1047743
  • Target See all TFPI Proteins
    TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 29-280, partial
    Origin
    • 14
    • 4
    • 4
    • 2
    • 1
    Human
    Source
    • 10
    • 9
    • 2
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This TFPI protein is labelled with GST tag.
    Application
    ELISA
    Sequence
    DSEEDEEHTI ITDTELPPLK LMHSFCAFKA DDGPCKAIMK RFFFNIFTRQ CEEFIYGGCE GNQNRFESLE ECKKMCTRDN ANRIIKTTLQ QEKPDFCFLE EDPGICRGYI TRYFYNNQTK QCERFKYGGC LGNMNNFETL EECKNICEDG PNGFQVDNYG TQLNAVNNSL TPQSTKVPSL FEFHGPSWCL TPADRGLCRA NENRFYYNSV IGKCRPFKYS GCGGNENNFT SKQECLRACK KGFIQRISKG GL
    Characteristics
    Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
    Purity
    90 %
    Top Product
    Discover our top product TFPI Protein
  • Comment

    The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    0.2-2 mg/mL
    Buffer
    Tris-based buffer, 50 % glycerol
    Handling Advice
    Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
  • van der Logt, Reitsma, Bertina: "Intron-exon organization of the human gene coding for the lipoprotein-associated coagulation inhibitor: the factor Xa dependent inhibitor of the extrinsic pathway of coagulation." in: Biochemistry, Vol. 30, Issue 6, pp. 1571-7, (1991) (PubMed).

    Girard, Warren, Novotny, Bejcek, Miletich, Broze: "Identification of the 1.4 kb and 4.0 kb messages for the lipoprotein associated coagulation inhibitor and expression of the encoded protein." in: Thrombosis research, Vol. 55, Issue 1, pp. 37-50, (1989) (PubMed).

    Wun, Kretzmer, Girard, Miletich, Broze: "Cloning and characterization of a cDNA coding for the lipoprotein-associated coagulation inhibitor shows that it consists of three tandem Kunitz-type inhibitory domains." in: The Journal of biological chemistry, Vol. 263, Issue 13, pp. 6001-4, (1988) (PubMed).

  • Target
    TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))
    Alternative Name
    Tissue factor pathway inhibitor protein (TFPI Products)
    Synonyms
    EPI Protein, LACI Protein, TFI Protein, TFPI1 Protein, A630013F22Rik Protein, AW552122 Protein, TFPI Protein, si:dz44f8.1 Protein, tfpib Protein, wu:fb92g01 Protein, zgc:152844 Protein, zgc:158592 Protein, tissue factor pathway inhibitor Protein, tissue factor pathway inhibitor a Protein, TFPI Protein, Tfpi Protein, tfpia Protein
    Background
    Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
    Molecular Weight
    56.3 kD
    UniProt
    P10646
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