Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-239), (partial) protein (GST tag)

Details for Product No. ABIN1047820
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Protein Name
Synonyms TNFSF14, CD258, HVEML, LIGHT, LTg, TR2, HVEM-L, Ly113
Protein Characteristics
AA 1-239, partial
Origin
Human
(15), (5), (1)
Source
Escherichia coli (E. coli)
(9), (7), (2), (1), (1), (1)
Protein Type Recombinant
Purification tag / Conjugate
GST tag
Application
ELISA
Pubmed 2 references available
Quantity 50 μg
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Sequence MEESVVRPSV FVVDGQTDIP FTRLGRSHRR QSCSVARVGL GLLLLLMGAG LAVQGWFLLQ LHWRLGEMVT RLPDGPAGSW EQLIQERRSH EVNPAAHLTG ANSSLTGSGG PLLWETQLGL AFLRGLSYHD GALVVTKAGY YYIYSKVQLG GVGCPLGLAS TITHGLYKRT PRYPEELELL VSQQSPCGRA TSSSRVWWDS SFLGGVVHLE AGEKVVVRVL DERLVRLRDG TRSYFGAFM
Characteristics Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
Purity 90 %
Alternative Name Tumor necrosis factor ligand superfamily member 14 protein
Background Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
Molecular Weight 53.6 kD
UniProt O43557
Comment

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions For Research Use only
Format Lyophilized
Concentration 0.2-2 mg/mL
Buffer Tris-based buffer, 50 % glycerol
Handling Advice Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
Storage -20 °C
Storage Comment Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
Supplier Images
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-239), (partial) protein (GST tag) Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-239), (partial)...
Background publications Harrop, McDonnell, Brigham-Burke et al.: "Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth." in: The Journal of biological chemistry, Vol. 273, Issue 42, pp. 27548-56, 1998 (PubMed).

Mauri, Ebner, Montgomery et al.: "LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator." in: Immunity, Vol. 8, Issue 1, pp. 21-30, 1998 (PubMed).

Validation Images
Catalog No. ABIN1047820
242.00 $
Plus shipping costs $45.00
Quantity
Price
50 μg
242.00 $
Plus shipping costs $45.00

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